<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25704

Description DUF803 domain-containing protein
SequenceMGRLGGLSPSGSIAIGVFVGLISTSLQAIGLTLQRKSHLLEDEKRPYDLRRPPYKRRRWQLGMLMFVVSNIVGSTIQITTLPLPVLSTLQASGLVFNTIFAALILREPFTRCSIFGTILVCLGAILIGTFGAIGEPAHTLNQLLVLLGRPPFLVWMAGTTGVVVLTILAARLLKLVSTPGRTREWMIQHCITIPCTPSFYGHNSPRIKMMRGMMYGSVSGILSAHSLLVAKSAVELIVRTIIDRVNQFNRWQSWIILLGLIALALTQLYYMHSGLKLCSTSILYPYVFCIYNVIAILDGLIYFDQGSRLSRLYAGLIALGTIILLSGVLCLSWRLEDATAHPNNVPAGPTPTPLAPGLGPLEEQLTPPEYFYYPDDEETALGERQPLLQQQQQQQQQQQQQQQQQQQQRKPSPLPHFYTRSLSHLPLRLRRSTQPSLETAEIWADLDDSGETLDPDLATPTSPLLTFTSFPHRHYRSKSSTIPSLSYNNNNNSSSSSSSSRKRSIGVSGCSENNPPLTNDPSSPSPPRLTLNNHQQRQIRRLPRASSWTWDLSSRRVRFAGRGSLRSSNGGGQCTPSRRRVSSPFIRDYRCGAVQREVCSAATAGAVGGVDGAGTCADSNARARARARDLGDVGVDHDGRDHRPQHRSQFTGPLRWLGQWVGSRRRRTEEGGNGRMKDSDDDGDGERERDR
Length691
PositionTail
OrganismParacoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Onygenales> Onygenales incertae sedis> Paracoccidioides.
Aromaticity0.07
Grand average of hydropathy-0.275
Instability index64.94
Isoelectric point9.85
Molecular weight76433.38
Publications
PubMed=22046142

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW

GO - Biological Function
magnesium ion transmembrane transporter activity	GO:0015095	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25704
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     156.39|      49|      53|     214|     263|       1
---------------------------------------------------------------------------
  214-  263 (77.51/63.41)	MYGSVSGI.LSAHSLLVAKSAVELIVRTIIDRVNQFNRwQSWIILL..GLIAL
  268-  319 (78.88/57.75)	LYYMHSGLkLCSTSILYPYVFCIYNVIAILDGLIYFDQ.GSRLSRLyaGLIAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     185.76|      42|     103|      11|      54|       2
---------------------------------------------------------------------------
   11-   54 (65.43/40.69)	GSIAIGVFVGLISTSLQAIGLTLQRK.SHLLEDEkrPYDLRRPPY
   74-  115 (59.00/31.23)	STIQITTLPLPVLSTLQASGLVFNTIfAALILRE..PFT.RCSIF
  116-  152 (61.33/32.73)	GTILVCLGAILIGT.FGAIGEPAHTL.NQLL......VLLGRPPF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     185.24|      56|      61|     413|     473|       4
---------------------------------------------------------------------------
  413-  473 (91.54/57.94)	PLPhfytrSLSHLPLRLRRSTQPSLETAEI.WADLDDSGETLDPDLATPTSPLLTFTSFPHR
  481-  537 (93.69/49.05)	TIP.....SLSYNNNNNSSSSSSSSRKRSIgVSGCSENNPPLTNDPSSPSPPRLTLNNHQQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     106.99|      18|      39|     563|     580|       5
---------------------------------------------------------------------------
  563-  580 (33.15/18.04)	GSLRSSNGGGQCTPSRRR
  605-  622 (27.43/13.61)	GAVGGVDGAGTCADSNAR
  631-  645 (18.63/ 6.79)	GDVGVDHDGRDHRPQ...
  674-  691 (27.78/13.88)	GRMKDSDDDGDGERERDR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25704 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AATAGAVGGVDGAGTCADSNARARARARDLGDVGVDHDGRDHRPQHRSQFTGPLRWLGQWVGSRRRRTEEGGNGRMKDSDDDGDGERERDR
2) LGERQPLLQQQQQQQQQQQQQQQQQQQQRKPSPLPHFYTRSLSHLPLRLRRSTQPSLETAEIWADLDDSGETLDPDLATPTSPLLTFTSFPHR
3) YRSKSSTIPSLSYNNNNNSSSSSSSSRKRSIGVSGCSENNPPLTNDPSSPSPPRLTLNNHQQRQ
601
381
475
691
473
538










Molecular Recognition Features






MoRF SequenceStartStop




1) ERERD
2) LPHFYTRSLSHLP
3) PPEYFYYPD
686
414
367
690
426
375