<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25636

Description Mediator of RNA polymerase II transcription subunit 17
SequenceMEKGDVLVDLDKLPMKRLEAIDETGNEHYPPDTSNEEQRLAAIRRIDFSWVIEKDAKKAKKAAEADTTQQAWPWQGLMESLQQAHQELSVVIDLIGTVEANDAMAVASTTKPKSQPNEILVDMAVCAATKLQCLRHLSRYFKQSATTMEQQFQKETRFYSSLIRLQQNWKVKRQRSVGSPGSEGFMFDLVDTSQLDTTTMPRLSPLSLIPIDQDSSGTLSVQIPQKCFHSLSLRFHGDIANNAESSAVKRKEGTLTNTTTGAENDVLENDDVNKSTEHAHSILRDIHKSIFEEQVFDMVIQETFIQSQGINVTGMCEDFLQLAIGQECSLCLSHDLSGQNNNSGTVGQEDHMDIDHTGNLAVATVNGKESSNKDVRGFPNPKSLEIYLLHVFHEGILRKLREKSRHVVRYQSSAQGTPDECGLLSHFCMTVSHRIFSSKVHLELESVVSRVPYLHLCSLPTWHSRTSSWSLCLKVPQPILATDRVRRPSDYSELKCKSRSQFGTKVILKDGQISLMGEGSPSIAGSLAGKPSDGRLVNSYNCDLEDLPMMLLQQVASQVIHWLHDEAVVLGMNATIDFLCLYLDLDQGETLGLVAHVDPDDTYGCVSWYLTLDHHPTEEGKMSAGSPELEERRFLGYLSPELLYSTLMDLVKLCSTGVQR
Length660
PositionHead
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.06
Grand average of hydropathy-0.362
Instability index44.42
Isoelectric point5.46
Molecular weight73694.57
Publications
PubMed=19936069
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25636
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      56.03|      14|      15|     144|     157|       1
---------------------------------------------------------------------------
  127-  139 (15.33/ 7.47)	.AATKLQCLR.HLSR
  144-  157 (22.75/14.58)	SATTMEQQFQ.KETR
  161-  175 (17.95/ 9.99)	SLIRLQQNWKvKRQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.99|      11|      21|     324|     334|       2
---------------------------------------------------------------------------
  324-  334 (21.52/14.08)	IGQECSLCLSH
  346-  356 (21.47/14.04)	VGQEDHMDIDH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     127.02|      37|     249|     201|     238|       3
---------------------------------------------------------------------------
  201-  238 (62.86/47.31)	PRLSPLSLiPI..DQDSSGTLSVQIPQKCFHSLSLRFHGD
  452-  490 (64.16/43.53)	PYLHLCSL.PTwhSRTSSWSLCLKVPQPILATDRVRRPSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.43|      32|     160|     358|     403|       6
---------------------------------------------------------------------------
  358-  394 (51.91/54.46)	GNLAvatvnGKESSNKDVRGFP.NPKSLEIYLL........HVFHE
  525-  565 (48.52/23.84)	GSLA.....GKPSDGRLVNSYNcDLEDLPMMLLqqvasqviHWLHD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25636 with Med17 domain of Kingdom Viridiplantae
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