<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25605

Description "DNA helicase hus2, putative"
SequenceMTRENHMRQNLSISAEGFKCDEKLPKINWSQHDKAHDNFSCQKKFLSSNFLYSLENQKPHSEGVMAMRLTCQIQSFQRLQSPQVEKAWHALSCLQISCRNYLQPGKTGPLKNANLLQDVGQRPTFCSSSDGGKYSECLHVHQNFSESGAKNNKSERYMGNYVPQDNATAAETGNGLQRQSQIKASAANNTESKTFSGSFSDHSVYTSHNKESAEASTDFIDDDDLLGNIDVDQIVMEHNQSNCTPPNSKFPSITPTADKHNFARSDEMFLPTELCQNCNHGFKLGLCPEAGNHLQEMKDMLIAVSNELLDNSTNLSSVQIEKLRQDRLQLNKQIQQLESYLRDKERQKSHFSASTANQNFQYETPQCAANKIDPMRFDAQVYLRNESGGYESWNTPSISFSSVDRFGISSGPIEREPYIPKFVEVNYIEGSNDPKWSSTNFPWTTKLEAYNKKVFGNHSFRPNQREVINATMSGFDVFVLMPTGGGKSLTYQLPALVCPGITLVISPLVSLIQDQIMHLLQANISAAYLSANMEWAEQQEILRELSSDYCKYKLLYVTPEKVAKSDVLLRNLESLNARGLLARIVIDEAHCVSQWGHDFRPDYKELGILKKKFEKTPVLALTATATASVKEDVVQALGLVDCIIFRQSFNRPNLWYSVVPKTKKCLDDIDKFIKENHFDECGIIYCLSRMDCEKVAEKLQECGHKAAFYHGNMDAAQRAFVQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGLRSSCVLYYSYSDYIRVKHMIVQGQIEQSPWTPGYNRINNTNSDRILEKNTENLLRMVSYCENDVDCRRILQLLHFGEKFNSGNCKKTCDNCSQIKALVEKDVTETAKQLVQLVKLTGQQFSSSHILEVYRGSLNQYVKKYRHETLSLHGAGKHLSKGEASRILRHLVTDDFLQEDVKKSDVYGSVSSILKVNESKAYNLCSGGQTIILRFPSTMKASKPSKFDATPAKGSLTSGKQSPPEVDSPAQAQPEVDLHLSAILYSALRMLRTLLVKEAGEGVMAYHIFGNATLQHLSKRIPRTKEELLEINGIGKAKVSKYGDRLLETIESTIKEYYKTDKNSSSSNGSNDSVKRRRDASRAPNGNAEEADDFTKSTGRSKKRVAKLQNKDTDIYTSRETNNSQCLDDDLDFEDSCHDFETNGSAIEAGKNDAGRVLPSWSTPGNKVKSSIPNLYQQYATKS
Length1233
PositionUnknown
OrganismRicinus communis (Castor bean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Malpighiales> Euphorbiaceae> Acalyphoideae> Acalypheae> Ricinus.
Aromaticity0.08
Grand average of hydropathy-0.597
Instability index44.60
Isoelectric point7.79
Molecular weight138697.62
Publications
PubMed=20729833

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25605
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     624.20|     154|     157|     820|     973|       1
---------------------------------------------------------------------------
  685-  833 (213.02/128.37)	YCLSRMDCEKVAeKLQECGHKaaFYHG.NM.....DAAQ.RAFVQ...KQWSKDEINIIC..ATVAFGMGINKPDVR.FVIHHSLPKSIEGYHQE......CGR.AGRDGLRSSCVLYY..SYSDYIR..VKHMIVQGQIeqspwtPGYNRINN.TNSDRILEKNTENLLRMVS
  834-  987 (246.89/149.99)	YCENDVDCRRIL.QLLHFGEK..FNSG.NCKKTCDNCSQIKALVE...KDVTETAKQLVQ..LVKLTGQQFSSSHIL.EVYRGSLNQYVKKYRHETLSLHGAGK.HLSKGEASRILRHL..VTDDFLQEDVKKSDVYGSV......SSILKVNE.SKAYNLCSGGQTIILRFPS
  988- 1135 (164.29/97.26)	TMKAS.KPSKFD.ATPAKGS...LTSGkQSPPEVDSPAQAQPEVDlhlSAILYSALRMLRtlLVKEAGEGVMAYHIFgNATLQHLSKRIPRTKEELLEINGIGKaKVSK.YGDRLLETIesTIKEYYKTDKNSSSSNGSN......DSVKRRRDaSRAPN..............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     133.76|      38|      50|       4|      41|       2
---------------------------------------------------------------------------
    4-   41 (69.49/38.37)	ENHMRQNLSISAEGFKCD.EKLPKINWSQHDKAHDNFSC
   55-   93 (64.26/34.99)	ENQKPHSEGVMAMRLTCQiQSFQRLQSPQVEKAWHALSC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.13|      21|      50|     548|     568|       3
---------------------------------------------------------------------------
  548-  568 (37.29/26.49)	DY.CKYKLLYVTPEKVAKSDVL
  598-  619 (32.84/22.38)	DFrPDYKELGILKKKFEKTPVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     224.03|      73|      78|     287|     364|       4
---------------------------------------------------------------------------
  287-  364 (107.43/84.89)	CpeAGNHLQEMK.DMLIAVSNELLD.NSTNLSSVQIEKLrqDRLQLNKQIQQLESYLrDKERQKSHFSAST....ANQNFQYET
  367-  445 (116.60/74.60)	C..AANKIDPMRfDAQVYLRNESGGyESWNTPSISFSSV..DRFGISSGPIEREPYI.PKFVEVNYIEGSNdpkwSSTNFPWTT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.67|      24|     960|     201|     224|       5
---------------------------------------------------------------------------
  201-  224 (42.51/29.44)	DHSVYTSHNKESAEASTDFIDDDD
 1162- 1185 (41.16/28.24)	DTDIYTSRETNNSQCLDDDLDFED
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25605 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ETNGSAIEAGKNDAGRVLPSWSTPGNKVKSSIPNLYQQYATKS
2) GAKNNKSERYMGNYVPQDNATAAETGNGLQRQSQIKASAANNTESK
3) YYKTDKNSSSSNGSNDSVKRRRDASRAPNGNAEEADDFTKSTGRSKKRVAKLQNKDTDIYTSRET
1191
148
1107
1233
193
1171










Molecular Recognition Features






MoRF SequenceStartStop




1) RVLPSWSTPGNKVKSSIPNLYQQYATKS
1206
1233