Description | Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MLQLVENLAEVIDNGSRDQHSDALITELNNQFEKCQQLLNSISSSINTKAMTVEGQKRKLEDSEQLLNQRRDLISKYRNSVEELLKSDP |
Length | 89 |
Position | Middle |
Organism | Ricinus communis (Castor bean) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Malpighiales> Euphorbiaceae> Acalyphoideae> Acalypheae> Ricinus. |
Aromaticity | 0.02 |
Grand average of hydropathy | -0.766 |
Instability index | 38.01 |
Isoelectric point | 4.91 |
Molecular weight | 10203.30 |
Publications | PubMed=20729833 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145 |
GO - Cellular Component | mediator complex GO:0016592 IBA:GO_Central |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP25600 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 35.77| 10| 25| 31| 40| 1 --------------------------------------------------------------------------- 31- 40 (19.09/10.54) QFEKCQQLLN 59- 68 (16.68/ 8.56) KLEDSEQLLN --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) HSDALITELNNQFEKCQQLLNSIS 2) KLEDSEQLLNQRRDLISKYRNSVEELLKSDP 3) MLQLVENLAEVIDNG | 20 59 1 | 43 89 15 |
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