<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25526

Description Uncharacterized protein
SequenceMGDGNNRSSNNNEKPEWLQQYNLIGKIGEGTYGLVFLAKTKSPANRGKSIAIKKFKQSKDGDGVSPTAIREIMLLREITHENVVKLVNVHINHTDMSLYLAFDYAEHDLYEIIRHHRDKVNNLIHQYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGEEHGVVKIADFGLARIYQAPLKALSDNGVVVTIWYRAPELLLGAKHYTSAIDMWAVGCIFAELLTLKPLFQGAEAKSASNPFQLDQLDKIFKVLGHPTLEKWPTLASLPHWQNDVHRIQEHKYENTGLHSVVPLSPKGAPFDLLSKMLEYDPQKRITAAQALEHDYFRSEPLPGRNALVPSQPGEKVINYPTRPVDTNTDFEGTTSLQPPQPVSSGNAVSGGIPGAHGVNNRSAPRPMPIGLQRMQTQGMTAYNLASQAGMGGGMNPGNIPMPRGVAQPHQQHQLRRKDPPGTGTGYPPQQKSRR
Length469
PositionKinase
OrganismPopulus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Malpighiales> Salicaceae> Saliceae> Populus.
Aromaticity0.07
Grand average of hydropathy-0.496
Instability index38.18
Isoelectric point9.23
Molecular weight52173.85
Publications
PubMed=16973872

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25526
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     163.88|      37|      37|     367|     403|       1
---------------------------------------------------------------------------
  338-  378 (56.07/30.26)	GRN.ALVPSQPGEKVINYPT..RPVD............tntdfeGTTSLQPPQPVS
  379-  415 (60.51/33.22)	SGN.AVSGGIPGAHGVNNRSAPRPMP.................iGLQRMQ.TQGMT
  416-  467 (47.30/24.40)	AYNlASQAGMGG..GMNPGNIP..MPrgvaqphqqhqlrrkdppGTGTGYPPQQKS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25526 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SEPLPGRNALVPSQPGEKVINYPTRPVDTNTDFEGTTSLQPPQPVSSGNAVSGGIPGAHGVNNRSAPRPMPIGLQRMQTQGMTAYNLASQAGMGGGMNPGNIPMPRGVAQPHQQHQLRRKDPPGTGTGYPPQQKSRR
333
469










Molecular Recognition Features






MoRF SequenceStartStop




1) GVAQPHQQHQLRRKDP
2) RGKSIAIKKFK
3) TGYPPQQKSRR
439
46
459
454
56
469