<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25523

Description Uncharacterized protein
SequenceMGDGNNRSNNNSEKPEWLQQYNLIGKIGEGTYGLVFLAKTKSPANCGKSIAIKKFKQSKDGDGVSPTAIREIMLLREITHENVVKLVNVHINHADMSLYLAFDYAEHDLYEIIRHHRDKGNTMINQYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGEEHGVVKIADFGLARIYQAPLKALSDNGVVVTIWYRAPELLLGAKHYTSAVDMWALGCIFAELLTLKPLFQGAEAKSTSIPFQIDQLDKIFKVLGHPTLEKWPTLASLPHWHNDVQHIQEHKYENTGLHGVVPLSPKSASFDLLSKMLEYDPRKRITAAQAIEHDYFRSEPLPGRNALVPSQPGEKVINYPTRPVDTNTDFEGTTSLQPPQPVSSGNAVSGGMPGAHGINSRSAPRPMSVGMQRMQSQGMAAYNLSSQAGMGGGMNPGNIPMPRGVAQPHQQHHLRRKDPPGTGTGYPPQQKSRR
Length469
PositionKinase
OrganismPopulus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Malpighiales> Salicaceae> Saliceae> Populus.
Aromaticity0.07
Grand average of hydropathy-0.471
Instability index41.60
Isoelectric point9.10
Molecular weight52038.72
Publications
PubMed=16973872

Function

Annotated function 
ECO:0000256	RuleBase:RU366036
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central
GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central

Interaction

Binary Interactions











Repeat regions





Repeats
>MDP25523
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     150.90|      37|      93|     337|     378|       1
---------------------------------------------------------------------------
  337-  378 (60.84/44.62)	PGrNALVP...SQPGEKVINYPTRpvdtNTDFEGTTSLQPPQPVS
  386-  403 (26.90/10.03)	...........GMPGAHGIN................SRSAPRPMS
  431-  467 (63.16/33.49)	PG.NIPMPrgvAQPHQQ...HHLR....RKDPPGTGTGYPPQQKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.81|      46|     129|     134|     186|       2
---------------------------------------------------------------------------
  134-  186 (69.50/74.40)	WQLLNGLNYLHSNwIIH.RDLKPSNilvmgEGeEHGVV....KIADFG.LARIYQ.APLK
  266-  318 (69.31/49.81)	WPTLASLPHWHND.VQHiQEHKYEN.....TG.LHGVVplspKSASFDlLSKMLEyDPRK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25523 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SEPLPGRNALVPSQPGEKVINYPTRPVDTNTDFEGTTSLQPPQPVSSGNAVSGGMPGAHGINSRSAPRPMSVGMQRMQSQGMAAYNLSSQAGMGGGMNPGNIPMPRGVAQPHQQHHLRRKDPPGTGTGYPPQQKSRR
333
469










Molecular Recognition Features






MoRF SequenceStartStop




1) GVAQPHQQHHLRRK
2) IAIKKF
3) YPPQQKSRR
439
50
461
452
55
469