<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25517

Description Mediator of RNA polymerase II transcription subunit 30
SequenceMATPLPQKGPGLAGMLSQQQQSHLPPGLGPGQPPMLPQGALREISPVFLCRIGQETVQDIVTRTMEIFQITRATQLPNGVTQSQAVYQDRFGKLQEHLRQLALLFRKLRLLYERCVEMTSDLQEEPSELVPYLREEMAPVRVEPCSPAVSQERQEVLEKMRQKNQEMKILMDQMRNLLWDVNAMLTLRK
Length189
PositionHead
OrganismSalmo salar (Atlantic salmon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Protacanthopterygii> Salmoniformes> Salmonidae> Salmoninae> Salmo.
Aromaticity0.04
Grand average of hydropathy-0.428
Instability index65.12
Isoelectric point7.72
Molecular weight21647.03
Publications
PubMed=20433749

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25517
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.88|      13|      17|       6|      18|       1
---------------------------------------------------------------------------
    6-   18 (25.99/10.33)	PQKGPGLAGMLSQ
   26-   38 (28.88/12.06)	PGLGPGQPPMLPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.06|      15|      17|      47|      63|       2
---------------------------------------------------------------------------
   47-   63 (20.51/26.17)	VFlcRIGQET.VQDIVTR
   67-   82 (21.55/16.79)	IF..QITRATqLPNGVTQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.98|      14|      17|     123|     136|       3
---------------------------------------------------------------------------
  123-  136 (24.84/13.15)	QEEP.SELVPYLREE
  141-  155 (20.14/ 9.58)	RVEPcSPAVSQERQE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25517 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MATPLPQKGPGLAGMLSQQQQSHLPPGLGPGQPPMLP
1
37










Molecular Recognition Features






MoRF SequenceStartStop




NANANA