<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25509

Description Predicted protein
SequenceMLEERSSNILLTDPMRMYRAKRDATRRRVTDKYSIEGFISSGTYGRVYKAKSRDGDGRIHAIKKFKPDKEGDVITYTGISQSAIREIALNRDISHENVVELKEVILEDKSIYMVFEYAEHDFLQLIHHHAQTLRQNILTNVLKSLTYQLFNGLLYLHNAHIIHRDLKPANILITSSGVVKIGDLGLARLTYQPLQPLFVGDKVVVTIWYRAPELLLGAKHYNKAVDVWAVGCVIAELVALRPLFKGEEAKLDSKKNVPFQKDQLLKIMDWLGTPDEREWPGLKDLPEYPNLKRLDVSVFGLMRNNSYPNRLSQWCAAHRMAGDPDAYDLMRQLFAYDPDNRLTCQEALQHKWFRVAPVPTENAFQNIPLQHIPPQRRITHDDAPSMIPLPTATSQAQTHVQAQLAQVQAQAQAQLAGSHPPSRGSVASFASLSGGAAGAGSGHARKKARMG
Length451
PositionKinase
OrganismPostia placenta (strain ATCC 44394 / Madison 698-R) (Brown rot fungus) (Poria monticola)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Polyporales> Dacryobolaceae> Postia.
Aromaticity0.08
Grand average of hydropathy-0.368
Instability index41.58
Isoelectric point9.29
Molecular weight50779.62
Publications
PubMed=19193860

Function

Annotated function 
GO - Cellular Component
euchromatin	GO:0000791	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IEA:EnsemblFungi

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25509
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.93|      15|      17|     353|     369|       1
---------------------------------------------------------------------------
  355-  369 (27.13/20.62)	VAP...VPTENAFQNIPL
  372-  389 (23.79/ 9.75)	IPPqrrITHDDAPSMIPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.50|      12|      16|     281|     294|       2
---------------------------------------------------------------------------
  281-  294 (19.15/19.82)	GLKDLPEYPNlkRL
  300-  311 (24.35/17.08)	GLMRNNSYPN..RL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.38|      18|      19|     191|     208|       4
---------------------------------------------------------------------------
  191-  202 (16.38/ 7.64)	..............YQPLQPLFVGDK
  203-  219 (28.56/18.83)	VVVTIW........YRA.PELLLGAK
  223-  248 (23.44/14.12)	KAVDVWavgcviaeLVALRPLFKGEE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25509 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FQNIPLQHIPPQRRITHDDAPSMIPLPTATSQAQTHVQAQLAQVQAQAQAQLAGSHPPSRGSVASFASLSGGAAGAGSGHARKKARMG
364
451










Molecular Recognition Features






MoRF SequenceStartStop




1) HARKKARM
2) RIHAI
3) YGRVY
443
58
44
450
62
48