<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25504
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MIEQTEHGNVLAVTYDDSSVTFYDPKTMAVLNGTDDTNTLTSLAHAGFQYPPDSAGSFPSRYRGGTKFDTSIAGLHISFSPSGCNAVTLDGEGQAQLRVMEHSYGAENGLYDENKFSAAVASLTLAFCRGCGSEFNTDDILLILKRQASPDAQISFINEVYRALGVNCNYTQENDKLMSHQYLPKCLSVQAALGFIDKYKSRNFASNVPWTILQLRHASVLYALFLQYLKGGVQAEPPDAGKISTCGKYAELFLTVRFDADAIRILLGNTKWALDLLHYVLNDLLDLADDLESLLSDQEAFAQKCQYTIPLISTSNQSHGHFLLILFVAVKTISSLPLIILLSSMSRAFLRFICRGLRGIQAGYATAPLTGDAGVYYAEIYRTLDTSPVRIDVYEKLLAGVDSTVRHVYHGAGFGDNERPGPEKELLVNGRIPPVLVTAVSTILRQTVPALKPDIDRMAIYMGDYSWLGLGSDRRAELYRRTRDVDIIKKIPFRSTASAGSDETQSGKHNPSQVRRRCVRCCEIMCGAYPPRPQLSSRMMYKLGYVRYCICGGGWTLESDFHR |
Length | 563 |
Position | Tail |
Organism | Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus>
Aspergillus subgen. Circumdati.
|
Aromaticity | 0.10 |
Grand average of hydropathy | -0.122 |
Instability index | 37.75 |
Isoelectric point | 6.67 |
Molecular weight | 62323.32 |
Publications | PubMed=25883274
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP25504
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 123.72| 27| 96| 378| 404| 1
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378- 404 (43.26/30.31) AEIY.RTLDTSPV.RIDVYEKLLAGVDST
450- 475 (44.54/31.44) A.LK.PDIDRMAI.YMGDYSWLGLGSDRR
476- 504 (35.92/23.89) AELYrRTRDVDIIkKIPFRSTASAGSDET
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 125.16| 37| 96| 27| 63| 2
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27- 63 (67.52/41.15) TMAVLNGT.DDTNTLTSLAHAGFQYPPDSAGSFPSR.YR
124- 162 (57.64/34.16) TLAFCRGCgSEFNTDDILLILKRQASPDAQISFINEvYR
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 38.96| 11| 25| 302| 312| 3
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302- 312 (21.02/13.64) AQKCQYTIPLI
329- 339 (17.93/10.67) AVKTISSLPLI
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