<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25487
Description |
"RNA polymerase II transcription mediator complex subunit Srb7, putative" |
Sequence | MADILTQLQTCLDQLATQFYATLCYLSTYHDHVPATVPPPSSGITDSMPPLAKIPRNQPSAAPMPAGAAAKQTAEQQGQTSPSLGISGAGGAAGGVGAETSTLPPGTNGATATTSLTPGQGDPNQPPIPDSPQLFLYRQKELARDLIIKEQQIEYLIGRLPGIGSSEAEQEARIRELESELRQVELAREKKAKELKKLGKRLESVLSTVERGIYSKQQRYGQD |
Length | 223 |
Position | Middle |
Organism | Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) (Penicillium stipitatum) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Trichocomaceae> Talaromyces>
Talaromyces sect. Talaromyces.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.509 |
Instability index | 50.85 |
Isoelectric point | 5.81 |
Molecular weight | 23820.58 |
Publications | PubMed=25676766
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 ARBA:ARBA00003669
ECO:0000256 RuleBase:RU366036
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP25487
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 60.58| 18| 20| 59| 76| 1
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59- 76 (30.92/14.55) PSAAPMPAGAAAKQTAEQ
82- 99 (29.66/13.69) PSLGISGAGGAAGGVGAE
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 74.43| 24| 41| 138| 163| 2
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138- 163 (36.46/34.23) RQKELARDliIKEQQIEYLIGRLPGI
182- 205 (37.97/28.27) RQVELARE..KKAKELKKLGKRLESV
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|