<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25474

Description "Cell cycle control protein Cwf15, putative"
SequenceMTTAHRPTFDPAQGKEALRGPAYHQRLLPAYMHLKTRQPGQGGAADQPRDLRAELLAAEAAHFAKTKGVTNESPAEPVPKLKRDLEEDREANLDAEDIEAKRRRILEETRDIDADSVGSDSDSSEEESDDEEDEAAELMRELEKIKQERQAQKEKEEREREAQEQEQREYDIARGNPLLNPQDFNIKRRWDDDVVFKNQARGSEVKKGPEFVNDLLRSDFHKRFMSSTMDSQATSKTLHNRINTDITQLLQRFENILAPSRVENSENANTAVGVYNLNVETTALIRAAEDLLSLTRYMKEAWLFEKLNTVGEDEHDKRRNQKLEEDVAGVREAVQRGLLGDNDTNGEGK
Length349
PositionHead
OrganismTalaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) (Penicillium stipitatum)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Trichocomaceae> Talaromyces> Talaromyces sect. Talaromyces.
Aromaticity0.05
Grand average of hydropathy-1.094
Instability index59.87
Isoelectric point4.94
Molecular weight39821.33
Publications
PubMed=25676766

Function

Annotated function Involved in pre-mRNA splicing. 
ECO:0000256	ARBA:ARBA00003777
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
spliceosomal complex	GO:0005681	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
mRNA splicing, via spliceosome	GO:0000398	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions











Repeat regions





Repeats

>MDP25474
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.76|      16|      18|      78|      95|       1
---------------------------------------------------------------------------
   78-   95 (22.93/18.08)	V.PKLKRDLEEDREanLDA
   98-  114 (22.83/11.40)	IeAKRRRILEETRD..IDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.59|      24|     190|      10|      33|       2
---------------------------------------------------------------------------
   10-   33 (45.10/29.44)	DPAQGKEALRGPAYHQRLLPAYMH
  198-  221 (42.49/27.36)	NQARGSEVKKGPEFVNDLLRSDFH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25474 with Med22 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MTTAHRPTFDPAQGKEALRGPAYHQRLLPAYMHLKTRQPGQGGAADQPRDLRAELLAAEAAHFAKTKGVTNESPAEPVPKLKRDLEEDREANLDAEDIEAKRRRILEETRDIDADSVGSDSDSSEEESDDEEDEAAELMRELEKIKQERQAQKEKEEREREAQEQEQREYDIARGNPL
1
178










Molecular Recognition Features






MoRF SequenceStartStop




1) KEALRGPAYHQRLLPAYMHLKTRQPGQ
2) QPRDLRAELLAAEAAHFA
15
47
41
64