<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25407

Description "Cdk activating kinase, putative (Fragment)"
SequenceWKMAGNFWQSSQYQQWLLDRQDLLRERHGDLQTLTEEEYQKLMIFFANLMQALGEQLKVKQQVIATATVYFKRFYVRNSLRCVDPLLMAPTCIFLASKVEEFGVISNSRLVSTCQTVVKNKFAHVYPQEFPYRINHVLECEFYLLEMMDCCLVLYHPYRPLVQYVHDIGHEDQLLSMAWKVVNDSLRTDVCLLHPPHQIALACLHVACVILQRDCKHWFADLCVDMEKILDITRQVLGLYDTWRNLDEKKELPPILAKVPKPKTQPSRPPSQGPNDPPPSQG
Length282
PositionKinase
OrganismIxodes scapularis (Black-legged tick) (Deer tick)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Parasitiformes> Ixodida> Ixodoidea> Ixodidae> Ixodinae> Ixodes.
Aromaticity0.10
Grand average of hydropathy-0.212
Instability index48.91
Isoelectric point6.85
Molecular weight32889.91
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IBA:GO_Central
kinase activity	GO:0016301	IEA:UniProtKB-KW

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25407
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.85|      18|     108|      76|      96|       2
---------------------------------------------------------------------------
   76-   96 (30.23/24.99)	VRNSLR...CvdpLLMAPTCIFLA
  182-  202 (30.62/16.68)	VNDSLRtdvC...LLHPPHQIALA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25407 with CycC domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




1) LPPILAKVPKPKT
252
264