<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25407

Description "Cdk activating kinase, putative (Fragment)"
SequenceWKMAGNFWQSSQYQQWLLDRQDLLRERHGDLQTLTEEEYQKLMIFFANLMQALGEQLKVKQQVIATATVYFKRFYVRNSLRCVDPLLMAPTCIFLASKVEEFGVISNSRLVSTCQTVVKNKFAHVYPQEFPYRINHVLECEFYLLEMMDCCLVLYHPYRPLVQYVHDIGHEDQLLSMAWKVVNDSLRTDVCLLHPPHQIALACLHVACVILQRDCKHWFADLCVDMEKILDITRQVLGLYDTWRNLDEKKELPPILAKVPKPKTQPSRPPSQGPNDPPPSQG
Length282
PositionKinase
OrganismIxodes scapularis (Black-legged tick) (Deer tick)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Parasitiformes> Ixodida> Ixodoidea> Ixodidae> Ixodinae> Ixodes.
Aromaticity0.10
Grand average of hydropathy-0.212
Instability index48.91
Isoelectric point6.85
Molecular weight32889.91
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IBA:GO_Central
kinase activity	GO:0016301	IEA:UniProtKB-KW

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25407
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.85|      18|     108|      76|      96|       2
---------------------------------------------------------------------------
   76-   96 (30.23/24.99)	VRNSLR...CvdpLLMAPTCIFLA
  182-  202 (30.62/16.68)	VNDSLRtdvC...LLHPPHQIALA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25407 with CycC domain of Kingdom Metazoa
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