<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25404

Description Mediator complex subunit 9 isoform C family protein
SequenceMATIEEVSGEILHLIYDVIRSIEKDSHDPNQKRDSYDSAVKIQELRGKLQLCRDLIHKLPGVDYTGEEQLRRVEALRRQLARKRELLVKYKSMCHFDTPDIKEAHGRPKIYDHYFGYFRETDLYRRTTAHSDPELRRFVLSSRARLDASALSAPELVEAALCCEDASFGRHHGRKIEDECCRRVRHLPPLTSVMLMDAWASSLGGKGYLREVVPHWTRYACSAETFDFVHLVYLASLGKSAPESFLHVVADRLRTVLPECALREVGILCSSLFKLKLRVADDTVLAAVARSTAEGLRSHGDRFDVISALKFLRSCEYYDAKLLAEITAYVHEVGGELAVAECAHFLAAFSSVAAYDGPTFRRLERRVADLLRDPRSTRDGHRAHPAESPRVKDVAKVLWALAHVGHDADNWILETAEEFLEQRSAPSDVFHVLDALQSFICLDFYPRRLIEEALSADVRHTIVSSHLRKPSKQLAFVSMSASVMLGDTLKGGPPLGDPPSSRTDRAQYERACFRDLADLFAARGLPASCILPHIHVAGVTFTVCPSSLTTRPVLDFRDLKGGSKQLNLSRDLIDAVSGTQKQRPDGGGSARASTRSTFVSVELLDGGVLVRGSESALRGIMRAKVVQLRRLGIKVVFATPGQVKAVSELPGVERDDWWVRFVKRCASDTDPQFYHSVGGGDAVVAT
Length686
PositionMiddle
OrganismIxodes scapularis (Black-legged tick) (Deer tick)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Parasitiformes> Ixodida> Ixodoidea> Ixodidae> Ixodinae> Ixodes.
Aromaticity0.07
Grand average of hydropathy-0.214
Instability index54.14
Isoelectric point8.24
Molecular weight76421.36
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25404
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     103.32|      27|      84|     273|     299|       1
---------------------------------------------------------------------------
  273-  299 (46.08/26.22)	F.KLKLRVAD.DTVLAAVAR..........STAEGLRSH
  360-  384 (38.69/20.89)	FrRLERRVAD....LLRDPR..........STRDGHRAH
  385-  417 (18.55/ 6.39)	P.AESPRVKDvAKVLWALAHvghdadnwilETAE.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.60|      36|      88|     116|     155|       2
---------------------------------------------------------------------------
  116-  155 (54.99/44.29)	GYFRETdLYRRTTAHSDPELRRFV.LSSRARLDASalsAPE
  207-  243 (62.62/38.05)	GYLREV.VPHWTRYACSAETFDFVhLVYLASLGKS...APE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.18|      43|     126|     301|     354|       3
---------------------------------------------------------------------------
  301-  354 (59.54/58.96)	DRFDVISALKflrS..C.EYYDAKLLAE.ITAYV.HEVGGelavaecAHfLA......AFSSVAA
  428-  481 (53.64/29.76)	DVFHVLDALQ...SfiClDFYPRRLIEEaLSADVrHTIVS.......SH.LRkpskqlAFVSMSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.37|      29|      40|       4|      33|       5
---------------------------------------------------------------------------
    4-   33 (45.55/34.96)	IEEVSGEiLHLIYDVIRSIEK.DSHDPNQKR
   42-   71 (46.81/31.07)	IQELRGK.LQLCRDLIHKLPGvDYTGEEQLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.72|      24|      45|     482|     505|       8
---------------------------------------------------------------------------
  482-  505 (44.28/31.79)	SVMLGDTLKGGPPLGDPPSSRTDR
  528-  551 (44.44/31.94)	SCILPHIHVAGVTFTVCPSSLTTR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25404 with Med9 domain of Kingdom Metazoa
Unable to open file!