<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25395

Description "Alginate regulatory protein AlgR3, putative"
SequenceMAAVIEVIGMLERTPITKDALERTRLGRYINELRKKTSNEQLARRAKDLVKSWRRLLPCGAPAERTGTPNGAPTPPVTLGPGPGPGVGPGPGPGLGPVVASKLLSPALRPARLAGVVAPRSISPSCSSVSNSPVPPAALAAATAAAPPRTRNGGFKPVSPACRSAPTSPGSPLAHPYPRSPTTGLEPVAKNNVANKRLRKSADRDGLKKAATTATASGASSGVPWTPPNGVHATAAATAAAVWDASIPSGNSAFESVRRSQCTTSVTSPRVMPKVKTTQQLIADLRAKSGANVSLDGVVVPPTLSPPTPAATRHAASRRPLKRAGNYSLLGTDDETSRTKSELMDRFLQSSAREPPNGPVSREIASILSALPDLSSFGNLEEEEEEEDAPRPPMEVTPAVEERFATERWEFVNGVYDHGGAWRGWEEVTTAESLGGDVLHILPYVNTDW
Length449
PositionUnknown
OrganismIxodes scapularis (Black-legged tick) (Deer tick)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Parasitiformes> Ixodida> Ixodoidea> Ixodidae> Ixodinae> Ixodes.
Aromaticity0.04
Grand average of hydropathy-0.400
Instability index63.08
Isoelectric point9.63
Molecular weight47066.62
Publications









Function






Annotated function


GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25395
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     172.59|      33|      33|     122|     154|       1
---------------------------------------------------------------------------
   78-  111 (46.79/15.91)	TLGPGPGPGV.....GPGPGPG...LGPVVASK.LLSPaLRPA
  112-  137 (42.96/13.98)	RLAGVVA........PRS.......ISPSCSSV.SNSP.VPPA
  138-  173 (51.53/18.31)	ALAAATAAAP.....PRTRNGGfkpVSPACRSA.PTSP.GSPL
  233-  269 (31.31/ 8.10)	ATAAATAAAVwdasiP.SGNSA...FESVRRSQcTTSV.TSP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.08|      19|      88|     301|     319|       2
---------------------------------------------------------------------------
  176-  197 (29.22/10.35)	PYPRSPTTglePVAKNNVANKR
  301-  319 (35.85/14.27)	PPTLSPPT...PAATRHAASRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     190.65|      59|     315|      17|      76|       4
---------------------------------------------------------------------------
   17-   76 (96.31/50.44)	TKDALERTR...LGRYINELRKKTSNEQLARRAKDLVKSWRRLLPCGApAERTGTPNGAPTPP
  332-  393 (94.34/45.46)	TDDETSRTKselMDRFLQSSAREPPNGPVSREIASILSALPDLSSFGN.LEEEEEEEDAPRPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.31|      12|      14|     409|     420|       6
---------------------------------------------------------------------------
  409-  420 (25.20/18.46)	WEFVNGVYDHGG
  425-  436 (22.11/15.32)	WEEVTTAESLGG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25395 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LPCGAPAERTGTPNGAPTPPVTLGPGPGPGVGPGPGPGLGPVVASKL
2) NVSLDGVVVPPTLSPPTPAATRHAASRRPLKRAGNYSLLGTDDET
3) PRSISPSCSSVSNSPVPPAALAAATAAAPPRTRNGGFKPVSPACRSAPTSPGSPLAHPYPRSPTTGLEPVAKNNVANKRLRKSADRDGLKKAATTATASGASSGVPWTPPNGVHATAAATAAAV
4) SAFESVRRSQCTTSVTSPRVMPKVKTTQQLIA
57
292
119
252
103
336
242
283










Molecular Recognition Features






MoRF SequenceStartStop




1) KRLRKSADRDGLK
2) LRPAR
3) WRRLLP
196
108
53
208
112
58