<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25394

Description "Mediator of RNA polymerase II transcription subunit, putative"
SequenceMDTSKTSSIKSLLLQAWRERWTDVRWGINIKNVLPRGVSGDVYDLADCILQEALVGPGPNNLFLSYLTHCLSAQVVSYGAVLSSIGRFQSFFKPPCILSLLQLLYSIQAKVTCHGNEEECIALCKAIVSVTHWLYMCMCHSISKIVELKQSTEHGLILEKACETLCFFSESTFLKSLLYIGKHEDSAVYSQLVQKQQELESKLSQSQGFNISKDTLECALNLVRLVDDMPHISLSSCVSGRVPKQPLVCSLNANVAIEAVLNPASDIQASVDHLLLMKKLLNLSSAELYCEIIRACFMGLANGSSEDLKWPAFTFLKVPQLLLKIHSARKDDRQWEEELEAGLMQLLNYTPLLDLTDSKCHCDCLQYLLNELQKVELLTEAQAKALMHRRQANTQKQNLARQGPQTSQAGATLILKAEPTVTSILKSLDADYSKNQDGLLGILCHMITGRSFELILSAAAATGKLNSFVKKLIKFNEYNKQISGETTRNAQTRTLLFDITFLMLCHIVQNYGIHSVVFNEETRDSFFTTWVPECLAEGGRYNCPEKMLAGCDPAKVDLLLAQLMNNDNDFMTNQVKWHEVCVNIPMAIKEILVAWEHGAISTDSVKMILDNVKSRICCLPVCISAWLCSYINVLHHQEQLKPMNMLQHFMTPLSTDASGNSEGGGDRPIPQEPHSLYKERSLLMTNIVKKMMYDLHPPQQSKLKGPLVISHGLTNKTPLWEIMDSVFSAAHARGWIDLRAIQSLDTLMCVGGPQWFCDTLVRQALKHDHLEDLHRAIDLSFGLFHIDIEQCALALLTQVLPSYLLWETRQDSLTEPRGSALARLTVLTTFAALQVRTSQPSVGTQRGGHKRPHWDMELEEAMDESKRVRPNKMRRGLNDSELLDDTPFALQCHSEENYRSLDPLSKAVVDTMRLLMVIASDSVISQRSVFPLLLFEQVVLCAGDEAHRVLQFAPLGLVPQLVRSMPHLMSHQLVLALSSLQTSRARKVAARATCQLQIARTLRNYTT
Length1007
PositionTail
OrganismIxodes scapularis (Black-legged tick) (Deer tick)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Parasitiformes> Ixodida> Ixodoidea> Ixodidae> Ixodinae> Ixodes.
Aromaticity0.06
Grand average of hydropathy-0.048
Instability index49.73
Isoelectric point6.56
Molecular weight112914.61
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25394
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.62|      31|      85|     261|     291|       1
---------------------------------------------------------------------------
  261-  291 (53.40/32.19)	LN..PASDIQASVDHLLLMKKLLN.LSSAELYCE
  347-  380 (47.22/27.61)	LNytPLLDLTDSKCHCDCLQYLLNeLQKVELLTE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.74|      31|     654|     198|     230|       4
---------------------------------------------------------------------------
  198-  230 (46.64/44.25)	ELESKLSQSQgfNISKDTLECALNLVRLVDDMP
  857-  887 (53.10/41.49)	ELEEAMDESK..RVRPNKMRRGLNDSELLDDTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.84|      30|      41|     634|     663|       7
---------------------------------------------------------------------------
  634-  663 (52.81/31.35)	LHHQEQLKPMNMLQHFMTPLSTDASGNSEG
  676-  705 (51.03/30.07)	LYKERSLLMTNIVKKMMYDLHPPQQSKLKG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25394 with Med24 domain of Kingdom Metazoa
Unable to open file!