<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25387

Description "Cofactor required for Sp1 transcriptional activation, putative"
SequenceMNPYMADLGINLDAVNSGLRAVKALRSTVGEVFRTLADGVPSSQGDENKEKNFILELQTTLGGVISRIRELETAVTLLGSPVAPLNLGSTGHLCQDPTLDRTSLYTDMIKSYRWFDKVHEHTSHASAILNQNSLKRSNSSLFPTKRLRRPLTNGHNFSPQNVDVFISSVQRQFVDMSIDVLRPCGGSAVLKITLSRTLRALVSLRGLIIEWVIVKGFNEDFYTDDDQLDMWTKSRYQVFQKVTDHANAAMLHFFSPQLPDLAVKSFLTWLHSYLNLFSTPCRRCGTRLQHNMPPTWRDVRNLDVYHETCRP
Length311
PositionTail
OrganismIxodes scapularis (Black-legged tick) (Deer tick)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Parasitiformes> Ixodida> Ixodoidea> Ixodidae> Ixodinae> Ixodes.
Aromaticity0.08
Grand average of hydropathy-0.268
Instability index41.88
Isoelectric point8.96
Molecular weight35207.80
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25387
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     320.78|     105|     121|      12|     125|       1
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   12-  125 (164.82/143.89)	LDAVNSGLRAVKALRS..TVGEVFRTLADGVPSSQGdenkEKNFI...LELQTTLGG.VISRI...RELETAVTLLGSPVAPLNL.GSTGHLCQDPtlDRTSLYTdmiKS.YRWFDKVHEHTSHA
  134-  249 (155.96/112.51)	LKRSNSSLFPTKRLRRplTNGHNFSPQNVDVFISSV....QRQFVdmsIDVLRPCGGsAVLKItlsRTLRALVSLRGLIIEWVIVkGFNEDFYTDD..DQLDMWT...KSrYQVFQKVTDHANAA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.08|      15|      25|     268|     282|       2
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  268-  282 (30.27/19.84)	TWLH.SYLNLFSTPCR
  295-  310 (25.81/15.96)	TWRDvRNLDVYHETCR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25387 with Med27 domain of Kingdom Metazoa
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