<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25288

Description "Pb, isoform A"
SequenceMQEVCSTLDTTPMGTQIKSESPLNPLQVQTGGQTALPVGVGVGGLVGQGTQQGAPAVPAVMLVNKMASNCDKRAADTAYWMAASEGGFINSQPSMAEFLNHLSPESPKMGTPVGGGGGGGVGVGGGVNVNVNVGVGYPVGVGPMPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGSLTPNSSLETGISSNLLGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDENQVIKKEAVSTSSKASPFGYESSTPSLVSFRRDSDAVIASANPPPTKGKKRYQNNANSIATPTPLTDSSSGGNVGAGGGGGASAGGYFPGYYPSPKQQMQQQQQLHPQQQQQQPQPQDYYGKYDIEFAASPHHNNPHKQQSLHAGEYLSPKPNAATFHQNSQQQQQHEQQFYYNYNDANGSAYMNHQQQQQQQHHHVGDFETPPINGPSNFNSGYYDNMSFQHQAQAQAHQQHQSVVFQQQQQHQQAPINHQQHMHHLGTGEAYSALGLQMENCDGYNNFGGPGSAGAGSAGAGVGVGYYEAGQQPPVPPHTHTHTHHPHHHVQVQAQAHDHLHAHHNPAAAAVQAGVGVGVGVGVGVGVVPPPPPPSHIHGFALNGGGQAVQSQAFVSGGGSAGGAAAISGLENSNSSSDFNFLSNLANDFAPEYYQLS
Length801
PositionKinase
OrganismDrosophila pseudoobscura pseudoobscura (Fruit fly)
KingdomMetazoa
Lineage
Aromaticity0.06
Grand average of hydropathy-0.777
Instability index55.23
Isoelectric point6.07
Molecular weight85156.75
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25288
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     441.33|      78|      79|     477|     554|       1
---------------------------------------------------------------------------
  357-  412 (53.97/15.98)	..................DIE.ESSPIKVKKKDENQ....VIKKE.............A..VSTSSKA.SPFGYESS....TPSL..VSFRRDSDA.....VIASA.
  414-  479 (48.75/13.77)	........PPPTKGKKRYQNN.ANSIATPTPLTDSSsggnVGAGGgggasaggyfpgyY..PSPKQ.......QMQQ....QQQLHPQ...................
  480-  554 (136.43/51.02)	...QQQQQPQPQDYYGKYDIEFAASPHHNNPHKQQS....LHAGE.............Y..LSPKPNA.ATFHQNSQ....QQQQHEQQFYYNYND.....ANGSAY
  557-  635 (97.84/34.62)	HQQQQQQQ...HHHVG..DFE...TPPINGPSNFNS.......GY.............YdnMSFQHQAqAQAHQQHQsvvfQQQQQHQQAPINHQQhmhhlGTGEAY
  670-  711 (59.53/18.35)	YYEAGQQPPVPPHTH.....THTHHPHH...HVQVQ....AQAHD.............H..LHAHHNP.A.....................................
  735-  769 (44.80/12.09)	.......PPPPSHIH.......................................................GFALNGG....GQAVQSQAFVSGGGS.....AGGAA.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     142.20|      35|      78|      23|      81|       2
---------------------------------------------------------------------------
   23-   58 (62.77/22.43)	LNPLQVQtGGQTALPVGVGVGGLVGQG....TQQGAPAVP
   99-  122 (37.46/30.73)	LNHLSPE.SPKMGTPVGGGGGGGVG...............
  124-  155 (41.97/10.38)	........GGGVNVNVNVGVGYPVGVGpmpqTPDGMDSVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.56|      13|      56|     657|     669|       3
---------------------------------------------------------------------------
  657-  669 (25.68/15.50)	AGAGSAGAGVGVG
  712-  724 (24.88/14.76)	AAAVQAGVGVGVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.32|      19|      77|     159|     178|       4
---------------------------------------------------------------------------
  160-  178 (33.94/26.03)	MKEKK.TSRKSSNNNN....QGDN
  243-  266 (24.38/10.20)	MKHKRqTLSKTDDEDNkdslKGDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.65|      13|      16|     274|     286|       5
---------------------------------------------------------------------------
  274-  286 (24.31/12.97)	NSKKSCQG..CELPS
  291-  305 (17.34/ 6.97)	DSTSNSRGhnNNTPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.80|      15|      25|     182|     196|       6
---------------------------------------------------------------------------
  182-  196 (27.89/19.34)	EFVPENGL..PRRLRTA
  208-  224 (23.91/15.50)	EFHFNKYLcrPRRIEIA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25288 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AGAGVGVGYYEAGQQPPVPPHTHTHTHHPHHHVQVQAQAHDHLHAHHNPAAA
2) MQEVCSTLDTTPMGTQIKSESPLNPLQVQTGG
3) PVGVGPMPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNT
4) QPSMAEFLNHLSPESPKMGTPVGGGGGGGV
5) SFRRDSDAVIASANPPPTKGKKRYQNNANSIATPTPLTDSSSGGNVGAGGGGGASAGGYFPGYYPSPKQQMQQQQQLHPQQQQQQPQPQDYYGKYDIEFAASPHHNNPHKQQSLHAGEYLSPKPNAATFHQNSQQQQQHEQQFYYNYNDANGSAYMNHQQQQQQQHHHVGDFETPPINGPSNFNSGYYDNMSFQHQAQAQAHQQHQSVVFQQQQQHQQAPINHQQHMHHLGTGEAYS
6) VKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGSLTPNSSLETGISSNLLGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDENQVIKKEAVSTSSKASPFGYESSTPSL
662
1
138
92
400
234
713
32
200
121
636
398










Molecular Recognition Features






MoRF SequenceStartStop




1) APEYYQLS
2) FYYNY
3) QPQDYYGKYDIEFA
4) SAGGYFPGYYPSP
5) TKGKKRYQN
794
542
486
454
417
801
546
499
466
425