<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25284

Description Mediator of RNA polymerase II transcription subunit 31
SequenceMAKMYGKGKTTVESEEQQKRRWQIELEFVQCLSNPNYLNFLAQRGYFKDQSFINYLKYLQYWKEPDYAKYLMYPMCLYFLDLLQYEHFRREIVNSQCCKFIDDQAILQWQHYTRKRIKLMENAAAAQQQQQQQQQQQLQQSNGGEAATAGEAAATGGMMATANGNGTASAAEAQPLGGSVQRGEPGQAQAVIPQQQQQQINGLATASNIKLELN
Length214
PositionMiddle
OrganismDrosophila pseudoobscura pseudoobscura (Fruit fly)
KingdomMetazoa
Lineage
Aromaticity0.10
Grand average of hydropathy-0.701
Instability index57.11
Isoelectric point7.61
Molecular weight24395.19
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25284
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.66|      19|      62|     126|     147|       1
---------------------------------------------------------------------------
  126-  147 (30.25/19.52)	AQQQQQQQQQQQLqqsNGGEAA
  188-  206 (34.41/15.43)	AQAVIPQQQQQQI...NGLATA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.73|      15|      18|      67|      81|       2
---------------------------------------------------------------------------
   67-   81 (30.52/21.45)	YAKY...LMYPMCLYFLD
   85-  102 (24.21/15.77)	YEHFrreIVNSQCCKFID
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25284 with Med31 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QQQQQQQQQQLQQSNGGEAATAGEAAATGGMMATANGNGTASAAEAQPLGGSVQRGEPGQAQAVIPQQQQQQ
128
199










Molecular Recognition Features






MoRF SequenceStartStop




1) AEAQPLGG
2) PGQAQAVI
171
185
178
192