<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25273

Description Similar
SequenceMVSLIDTIEAAAEKQKQSQAVATNSSASSSSCSSSFSASPPSSSVGSPSPGAPKTNLTASGKPKEKRRNNEKRKEKSRDAARCRRSKETEIFMELSAALPLKTDDVNQLDKASVMRITIAFLKIREMLQFVPSLRDCNDAIKQDIETAEDQQEVKPKLEMGSEDWLNGAEARELLKQTMDGFLLVLSHEGDITYVSENVVEYLGITKIDTLGQQIWEYSHQCDHAEIKEALSLKRELAQKVKDEPQQNSGVSTHHRDLFVRLKCTLTSRGRSINIKSASYKVIHITGHLVVNAKGERLLMAIGRPIPHPSNIEIPLGTSTFLTKHSLDMRFTYVDDKMHDLLGYLPKDLLDTSLFSCQHGADSERLMATFKSVLSKGQGETSRYRFLGKYGGYCWILSQATIVYDKLKPQSVVCVNYVISNLENKHEIYSLAQQTAASEQKEQHHQAAETEKEPEKAADPEIILQETKETANTPIPSELQAKPLQIESEKAEKTIEETKTTATIPPVTATSTADQIKQLPESNPYKQILQAELLIKRENHSPGPRTITAQLLSGSSSGLRPEEKRPKSVTASVLRPSPAPPLTPPPTAVLCKKTPLGVEPTLPPTTTATAAIISSSNQQLQIAQQTQLQNPQQPAQDMSKGFCSLFADDGRGLTMLKEEPDDLSHHLASTNCIQLDEMTPFSDMLVGLMGTCLLPEDINSLDSTTCSTTASGQHYQSPSSSSTSAPSNTSSNNNSYANSPLSPLTPTPTATASNPSHQQQQQQHHNQQQQQQQQQQQHHPQHHDNSNSSSNIDPLFNYREESNDTSCSQHLHSPSITSKSPEDSSLPSLCSPNSLTQEDDFSFEAFAMRAPYIPIDDDMPLLTETDLMWCPPEDLQTMVPKEIDAIQQQLQQLQQQHHQQYAGNTGYQQQQQQPQLQQQHFSNSLCSSPASTVSSLSPSPVQQHHQQQQAAVFTSDSSELAALLCGSGNGTLSILAGSGVTVAEECNERLQQHQQSGNEFRTFQQLQQELQLQEEQQQRQQQQQQQQQQQQQQQLLSLNIECKKEKYDVQMGGSLCHPMEDAFENDYSKDSANLDCWDLIQMQVVDTEPVSPNAASPAPCKVSAIQMLQQQQQLQQQNIILNAVPLITIQNNKELMQQQQQQEQLQQPAIKLLNGASIAPVTTKATIRLVESKPPTTTQPRVAKVNLVPQQQQQHGNKRHLNSATGAGNPVESKRLKSGTLCLDVQSPQLLQQLIGKDPAQQQTQAAKRAGSERWQQSAESKQQKQQQQQSNSVLKNLLVSGRDDDDSEAMIIDEDNSLEQPTPLGKYGLPLHCHTSTSSVLRDYHHNPLISGTNFQLSPVFGGSDSSRGDGETGSVLSLDDSVPPGLTACDTDASSDSGIDENSLVDGASGSPRKRLTSSSTSTNQAESAPPALDVETPVTHKSVEEELEGCGSGSNAPSRKTSISFLDSSNPLLHTPAMMDLVNDDYIMGEGGFEFSDNQLEQVLGWPEIA
Length1493
PositionKinase
OrganismDrosophila simulans (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.04
Grand average of hydropathy-0.691
Instability index65.91
Isoelectric point5.22
Molecular weight164095.49
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
protein dimerization activity	GO:0046983	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25273
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            10|     564.25|      64|     135|     770|     833|       1
---------------------------------------------------------------------------
  433-  507 (43.00/13.93)	.QQ....taasEQ.KEQHHQAAE.................TEKEPEKAA..D................PeiI...L...QET......KETANTPIPSELQA.....kP..lQI...........ESekaeK.........T............IEE.............TKTTA.TIPPV
  510-  586 (39.91/12.37)	TST........AD.QIKQLP.....................ESNPYKQIlqA................E..L...L...IKR......EN..........HS......PgprTI...........TA....QllsgsssglR............PEEkrpksvtasvlrpSPAPP.LTPPP
  621-  707 (42.09/13.47)	QIA........QQ.TQLQNPQ.Q.................PAQDMSKGF..C................S..L...F.adDGRgltmlkEEPDDL..SHHLAStnciqlD...EM...........TP....F.........SdmlvglmgtcllPED............iNSLDStTCS..
  770-  833 (122.74/54.27)	QQQ........QQ.QQQHHPQHH.................DNSNSSSNI..D................P..L...F...NYR......EESNDTSCSQHLHS......P...SI...........TS....K.........S............PED.............SSLPS.LCSPN
  887-  939 (69.01/27.09)	QQQ.......lQQlQQQHHQQYA.................GNT...G.................................YQ......QQQQQPQLQQQHFS......N...SL...........CS..............S............PA..............STVSS.L.SPS
  942-  986 (47.19/16.05)	QQH........HQ.QQQAAVFTS.................D....SSEL..A................A..L...L...................CGSGNGT......L...SI...........LA....G.........S..............G.............VTVAE.EC...
 1018- 1103 (60.80/22.93)	QRQ........QQ.QQQQQQQQQ.................QQQLLSLNI..EckkekydvqmggslchP..MedaF.enDYS......KDSANLDCWDLIQM......Q...VV...........DT....E.......pvS............PNA.............AS.PA.PCKVS
 1110- 1186 (51.64/18.30)	QQQ........QL.QQQ..........................NIILNA..V................P..L...ItiqNNK......ELMQQQQQQEQLQQ......P...AIkllngasiapvTT....K.........A....tirlveskPPT.............TTQPR.VAKVN
 1187- 1233 (46.45/15.67)	LVP........QQ.QQQHGNKRH.................LNSATGAG...N................P..V...E...SKR......LKSG.TLC.LDVQS......P...QL...........LQ....Q.................................................
 1256- 1332 (41.41/13.13)	.QQsaeskqqkQQ.QQQSNSVLKnllvsgrddddseamiiDEDNSLEQP..T................P..L...G...KY...............GLPLHC......H...TS...........TS....S.........V............LRD.............YHHNP.LIS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     140.88|      42|      44|    1363|    1406|       2
---------------------------------------------------------------------------
 1339- 1359 (22.43/ 7.76)	......................SPVFG.GSDS..S.RGDGETGSV.LS
 1363- 1406 (63.17/49.21)	SVPPGLTAcDTDASSDSgIDENSLVDG.ASGS..P.RKRLTSSSTSTN
 1410- 1453 (55.28/32.78)	SAPPALDV.ETPVTHKS.VEEE..LEGcGSGSnaPsRKTSISFLDSSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.23|      18|      19|     715|     732|       3
---------------------------------------------------------------------------
  715-  732 (34.34/15.30)	Y.QSPSSSSTSAPSNTSSN
  736-  754 (29.89/12.33)	YaNSPLSPLTPTPTATASN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.80|      12|      15|     988|     999|       4
---------------------------------------------------------------------------
  988-  999 (21.71/10.62)	ERLQQHQQSGNE
 1004- 1015 (20.09/ 9.13)	QQLQQELQLQEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.80|      15|      16|     349|     363|       5
---------------------------------------------------------------------------
  349-  363 (27.38/17.27)	LLDT..SLFSCQHGADS
  366-  382 (20.42/10.79)	LMATfkSVLSKGQGETS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.64|      23|     136|     182|     204|       6
---------------------------------------------------------------------------
  182-  204 (39.40/34.71)	FLLVLSHEGDITYVSENVVEYLG
  321-  343 (42.24/37.86)	FLTKHSLDMRFTYVDDKMHDLLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.47|      16|      18|     839|     856|       7
---------------------------------------------------------------------------
  839-  856 (25.90/22.89)	DDFSF..EAFAMRAPyiPID
  857-  874 (29.57/18.22)	DDMPLltETDLMWCP..PED
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25273 with Med12 domain of Kingdom Metazoa
Unable to open file!