<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25262

Description GD19330
SequenceMVWCLPYGGQSAGAQFVPPMGPFLQPQKSDGDDRKDCHWWEVEWSLVRTWPKGFAAAHGCFDDISERRQLRDQTSVQRHCILICNSPPYQMPTTESWKYPGKSCEQLAALFNERKINLSIIAPRKMPVLFKLFMKADGDQPITSKNYAKNIRHLVLLKGYSLKERAPSPNSMAAQMAAPNAAQATVQQQQQQQQNQAGRHIDSRSGHAHGHRSTSPATSSIYSATTSTWHSSSARHGMYLNQPGQARPPFMQGAGNVGGVGQGGGMQQNPNSALISRINAPPNQTVTSLQQQQQQQAQQQQQQQAQQQQQQRMQMLSQQQMLNHQQLQQQQQLAQQQQQQQQGQQQQQGNPNAGNNMMPASNTGNMSNPQQQQQQVGQQSNPQQQVNPQQQQQGNSQQEQASLREKIWTGILEWSEKPKSDQQKIPHTLQCTVCTNIKDGEPEIKAENWPPKLLMQLMPKHLVGNIGGQFLKDSKMVVFRPTPGEALDSLAKMMTSGYAGCVHFSSIPNSPACDLKVLILLYTPDRNAFLGFIPNNQAMFVERLRKVIQQKQHGNMQQQQQQQQMMQQQGKSPMELQHQQQQQQQQMQQDNSQHHTTTSSNS
Length602
PositionUnknown
OrganismDrosophila simulans (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.05
Grand average of hydropathy-0.954
Instability index66.92
Isoelectric point9.42
Molecular weight67791.30
Publications
PubMed=17994087

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process
nervous system development	GO:0007399	IEA:EnsemblMetazoa
positive regulation of antibacterial peptide biosynthetic process	GO:0006963	IEA:EnsemblMetazoa

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP25262
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.05|      13|      15|     290|     303|       1
---------------------------------------------------------------------------
  290-  303 (25.81/ 7.18)	QQQQQQqAQQQQQQ
  337-  349 (30.24/ 6.31)	QQQQQQ.GQQQQQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.02|      20|      24|     552|     571|       2
---------------------------------------------------------------------------
  362-  381 (36.10/ 7.96)	NTGNMSNPQQQQQQVGQQSN
  552-  571 (46.37/12.21)	QHGNMQQQQQQQQMMQQQGK
  577-  593 (34.55/ 7.32)	QH...QQQQQQQQMQQDNSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     229.91|      75|     201|     179|     259|       3
---------------------------------------------------------------------------
  179-  259 (125.59/62.09)	PNA....................AQATVQQQQQQ....QQNQAGrhidSRSGHAHG..HRSTSPATSS..IYSATTSTWhSSSARHGMYlNQPGQARPP..FMQ.....GAGNVGG
  359-  468 (104.32/40.27)	PASntgnmsnpqqqqqqvgqqsnPQQQVNPQQQQqgnsQQEQAS....LREKIWTGilEWSEKPKSDQqkIPHTLQCTV.CTNIKDGEP.EIKAENWPPklLMQlmpkhLVGNIGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.94|      14|      15|     306|     319|       6
---------------------------------------------------------------------------
  306-  319 (26.29/ 8.04)	QQQQQQRMQMLSQQ
  323-  336 (25.65/ 7.66)	NHQQLQQQQQLAQQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP25262 with Med25 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) APSPNSMAAQMAAPNAAQATVQQQQQQQQNQAGRHIDSRSGHAHGHRSTSPATSSIYSATTSTWHSSSARHGMYLNQPGQARPPFMQGAGNVGGVGQGGGMQQNPNSALISRINAPPNQTVTSLQQQQQQQAQQQQQQQAQQQQQQRMQMLSQQQMLNHQQLQQQQQLAQQQQQQQQGQQQQQGNPNAGNNMMPASNTGNMSNPQQQQQQVGQQSNPQQQVNPQQQQQGNSQQEQASLREKIWTGILEWSEKPKSDQQKIPHTLQCT
2) QQKQHGNMQQQQQQQQMMQQQGKSPMELQHQQQQQQQQMQQDNSQHHTTTSSNS
166
549
432
602

Molecular Recognition Features

MoRF SequenceStartStop
NANANA