<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25251

Description GD11721
SequenceMETQVIDTVNEFLKVDSLDEAFVSVIVFKPNSEQERATRFANDLVTAFGNVAQENREQVLRLYLLRAAGASGYHIKVLMAALVKLVDAHVITARMLCDKVLMCEKLDFEHRTFWIESFRLIKRVIVQVDYKGVREIMKVCRDKAQWFPLNVNVTYMPQLLAVEDILRFIFDRNNCLLPAYFIANEIMRPFPYHWKLNRLMTDFVEEFRTTAQMVSIIGHASMLPIVEHFGYADHMMNSWRLDHNTLKFNFKGSLPYEPELLEEQKPLLRYVLEQPYSREMVSQMLNLQKHQKQRYNALEEQLVNLIVQAMEMTEANDASAGSGFNSSDEQITPYEWMWLHLSSQLIYFVLFQFVSFMHIVLALHEKLSKLELRKGRDQLMWILLQFISGSIQKNPITNFLPVFRLFDLLYPELEPLKLPDINKSSMVRHMAPICVWIHLMKKARVENMNITRPLPIALKNHYDFLQHLVTANTMMNMTLGNDFRIILICNAYSTNQEYFGRPMGLLLDALNGTSKSPNGGQIPAVTFSVTVLDSLTVHSKMSLIHSFVTQMLKQAQTKGQVPAAALLETYARLLVYTEIESLGIKGFLSQLMPTVFKNHAWAMLHTLMEMFSYRLHHVPTHYRVQLLSLLHSLSSVPQTNKMQLNLCFESTALRLITSIGSAEFQPQFSRYFNDKSPGAVASNESEELNRVLILTLARSMHVHGGGDEMQGWCKDFLSNIIQHTPHSWPMHSLACFPPALNEYFTQNNQPPENKQQLKKAVEEEYRTWTSMTNENDIIAHFLRPTTNPLFLCLLFKIIWETENISPVAYKILEGISARALSTHLRKFCDYLVAEVASSSDGRDFIHKCVDTINNMIWKFNVVTIDRVVLCLALRTHEGNEAQVCFLIIQLLLLKASELRNRVQEFCKDNNPDHWKQSNWQDKHLSFHQKYPEKFALDESASQIPLPVYFSNVCLRFLPVLDVVVHRFIELTITNVHQILGFILDHLSILYKFHDRPITYLYNTLHYYERILRDRPALKKKLVGAITSAFSEIRPPNWSVSEPYKVYLQSQDSLWTPELSYYMSLIRRLADTISGKNVFYSTDWRFNEFPNAPTHALYVTCVELLGLPVAPPLVASNLIDVIVSGYAVIPQKDIHSYINAVGIVLAALPEPYWSGIYDRLQDMLNTPNMLNWTYRFNAFELFNFKTVREAMLEKTYAVVLAVAHSVFHHMGAFKLAAMTRYLKEKLKPCVRTEQQLLYLCHVFGPFLQRIELEKPNAVAGIAVLLYEILEIVDKQHGPKPLQYMDQICDFLYHIKYIHVGNIIKNESEAIIKRLRPLLQMRLRFITHLNLEDIHTEKINDNTSNNAITSQTQSPMQTQHQQQPQQPHQQQQQTHQQPQQPHQQQQQQQQQQQQQMQQQQINAVQTTSVPLGSGGNLQQQQQINQQQQMYMQHMQQHQHMQNMRHN
Length1444
PositionTail
OrganismDrosophila simulans (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.10
Grand average of hydropathy-0.186
Instability index43.06
Isoelectric point7.51
Molecular weight167609.92
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25251
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.53|      12|      19|    1363|    1374|       1
---------------------------------------------------------------------------
 1389- 1400 (24.28/ 9.44)	QQQQQMQQ.QQIN
 1416- 1428 (20.25/ 6.81)	QQQQQINQqQQMY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.83|      19|      19|    1349|    1367|       2
---------------------------------------------------------------------------
 1349- 1366 (34.49/17.13)	....QT.QSPMQT..................QHQQQPQQPH
 1367- 1388 (27.54/12.18)	QqqqQThQQP.QQ..................PHQQQQQQQQ
 1403- 1437 (21.79/ 8.09)	Q...TT.SVPLGSggnlqqqqqinqqqqmymQHMQQHQ..H
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.51|      15|      17|     609|     625|       3
---------------------------------------------------------------------------
  611-  625 (29.02/21.36)	FS..YRLHHVPTHYRVQ
  627-  643 (20.49/ 6.05)	LSllHSLSSVPQTNKMQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     169.36|      52|      76|     775|     828|       4
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  775-  828 (84.32/67.60)	NDIIAHFLRPTTNPLFLCLLFKIiwETENISPVAYKILE..GISARALSTHLRKFC
  853-  906 (85.04/60.02)	NNMIWKFNVVTIDRVVLCLALRT..HEGNEAQVCFLIIQllLLKASELRNRVQEFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.87|      15|      16|    1078|    1092|       6
---------------------------------------------------------------------------
 1078- 1092 (30.96/18.52)	FYSTDWRFNEFPNAP
 1096- 1110 (26.91/15.17)	LYVTCVELLGLPVAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.63|      30|      36|    1278|    1309|       7
---------------------------------------------------------------------------
 1278- 1309 (51.57/40.78)	KPLQYMDqiCDFLYHIKY..IHVGNIIKNESE.AI
 1314- 1346 (44.06/27.99)	RPLLQMR..LRFITHLNLedIHTEKINDNTSNnAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.69|      11|      36|     344|     355|       8
---------------------------------------------------------------------------
  344-  355 (15.49/12.98)	QLIYfVLFQFVS
  378-  388 (20.19/10.82)	QLMW.ILLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.32|      32|      37|     520|     552|      10
---------------------------------------------------------------------------
  520-  552 (51.30/37.98)	GQIPAVTFSVTvLDSLTVHSKM.SL.IHSFVTQML
  559-  592 (45.03/28.35)	GQVPAAALLET.YARLLVYTEIeSLgIKGFLSQLM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.31|      21|      26|     951|     976|      11
---------------------------------------------------------------------------
  962-  983 (30.55/18.47)	VVVHRFIELTITNVH.......qILGF..IL
  987- 1017 (24.76/18.85)	SILYKFHDRPITYLYntlhyyerILRDrpAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.78|      21|      26|     438|     458|      13
---------------------------------------------------------------------------
  423-  435 (17.45/ 7.69)	...KSSMVRHMA.....PICV
  438-  458 (35.78/23.87)	HLMKKARVENMNITRPLPIAL
  467-  487 (34.55/22.79)	HLVTANTMMNMTLGNDFRIIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     150.32|      40|      68|    1125|    1165|      14
---------------------------------------------------------------------------
 1022- 1055 (25.70/10.18)	...............VGAI.TSAFSEirpPNWSvsepyKVYLQSQDSLWT
 1125- 1165 (68.50/43.83)	YAVIpQKDIHSYINAVGIV.LAALPE...PYWS.....GIYDRLQDMLNT
 1195- 1231 (56.12/30.82)	YAVV.LAVAHSVFHHMGAFkLAAMTR....Y........LKEKLKPCVRT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.08|      14|     765|     177|     191|      15
---------------------------------------------------------------------------
  177-  191 (24.59/22.66)	LPAYFiANEIMRPFP
  945-  958 (28.49/20.49)	LPVYF.SNVCLRFLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.56|      39|     608|      34|      74|      16
---------------------------------------------------------------------------
   34-   74 (61.21/44.63)	QERATRFANDlvTAFGNVAQENREQVLRLYLLRAAGASGYH
  665-  703 (67.35/43.36)	QPQFSRYFND..KSPGAVASNESEELNRVLILTLARSMHVH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.68|      14|      19|     200|     213|      18
---------------------------------------------------------------------------
  200-  213 (25.26/22.78)	MTDFVEEFRTTAQM
  222-  235 (27.42/25.60)	MLPIVEHFGYADHM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.19|      16|      23|     255|     270|      19
---------------------------------------------------------------------------
  255-  270 (30.47/19.52)	PYEPEL....LEEQK.PLLRY
  275-  295 (20.72/10.72)	PYSREMvsqmLNLQKhQKQRY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25251 with Med23 domain of Kingdom Metazoa
Unable to open file!