<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25236

Description Uncharacterized protein
SequenceMNQNQIQQLTSHLSQALDQNYDVVNLEAVLSVICALEGTTITKEQLEATRLAKYINHLRRRTKNEQLARRAKSLLKRWREMVGIQQTATDSQPAPSQPLTAGESAVVVVPSQQSSSPLAPPQLPINLQKNFVDVSLEQQQPLALPTVTVPSSHHTNFSNLINNIASKSDESKPFKFQRESGPIIDHSSNSVSNSTAADRFTDAAIVIDIVSDSNDNDGVVGGGLSVPANVPARNKKLKKDKRRRERESQRPKATLLNRNEVMGQQSRYATKINCAPYKDGKAQAVIPTDAAEILSLSNSSMSSILSGDVTVGNSHSKSMPPRPNNTSELTFAGRFKSVSQPESAVLNGHQFRGTEHLAPITFDDSITNDSNISFSRLSPTPTPSLFPFEERRKALEEAGKQQIEISVLVPPSTTTSSLGNEQSNRSNDFIEGGAASRGILPQIPKKRGRKKGSKGVDSLIAKESSSLSQQIFFGSGVKKVKTTKELFNELQSRKLSNVVQSVNNLSNASSDRDREEALSSRSLQPRPTSSCSEASMHSPQILDTYSSNITLMDADKFSNQNEDIGNTDSDTITSEPSRDSQKSRGNKATSSLESNSNSLQTPSATTGFPNQTHNDVTTQLMHVVHSLGSPPSVGDTEKMYQSQIVPCTCIVVEEEVDPSAEQTISADRLDSEKVTPTGPDSNVLPRDDEAQGDSIQKLERNVADDKTVLPAPQKPIKSIFDLDFDEDDDPLQSIIRDLRPPTVDLEAANGDVKSMMTTSANVITATSGITDGAPVHTDGMDLDQDAAEATLVPLPIFTVHEDPDCMAKERFLVQTNKVTNFHINALHNYCVPNINGNWDGVETASESISSLELYAVTDGADVVPKYGSLTCERIPKDLSGLKFARSISRIKTFKSYLPPFLGVAKCLPTCRRANRQRRRFKESKMQPKSPEISCKLEESESELPFLQLKNENVSIISKSSPSPLQVDVNVGDNIEVVTNFDEGSIDDEIHNNSSFRGPSENENSYNLLKLANDDDLPLEVGANGEMEFRENSRCSSSCSNSSLIKTQQTINAKLRSQQITDQYVIERNRKKRRKTREKEQKPRIKRIKIAINGKVTSQRQISNISSSNNSSDNEDKERGSDTLSLSDDINASQTHSPASNEDEHDDSFQSGTTTFDSIVADEDVDGDGDADGDGDGVLENDYENSDDEEYAIVQRPVACGTSSNHIVLTIKKTPSKINSPNSISAVSPITGSEIVPGSAKKSYFINMIDPNTKPAVQSSSKENEAIVEAEPQLSLENAKPENIIDNRSLLSSQTYCIGSYRRRLHRLRRRRLRIEKSAKLRNTIDIELNHLFISNAERSAPLSETRLHRKLFYNDELCRQNNLGEKERILDYSSSSSSSDNSDIPSDSDEEDNSSSTNEADNIQVAKHKTNIINIETDIKASASKDAAKQEDEEPCESSSDNDNGDDDDFVKEDFANLDTNIEIDTVNNLPLHNNGLLPSFNSICAENPPRSMLPSAALTDEPETNPKPQIASLKSLQNENCDDVNNLYYNNNNLDVIKNSLVPSPILNDSIRESVTSNISSIILASDNKSSIQTNSPGITELIRPDCQTGIRAVAASDKLTSAKEDSRSSQVHQFKEWHQVLQLPSYNDEPLIVLPYVVLE
Length1642
PositionUnknown
OrganismDrosophila willistoni (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.04
Grand average of hydropathy-0.692
Instability index58.98
Isoelectric point5.08
Molecular weight180384.16
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IEA:EnsemblMetazoa
mediator complex	GO:0016592	IEA:InterPro
nucleolus	GO:0005730	IEA:EnsemblMetazoa
pericentric heterochromatin	GO:0005721	IEA:EnsemblMetazoa
polytene chromosome chromocenter	GO:0005701	IEA:EnsemblMetazoa

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IEA:EnsemblMetazoa
regulation of transcription by RNA polymerase II	GO:0006357	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25236
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     372.44|      95|     287|    1092|    1186|       1
---------------------------------------------------------------------------
  629-  704 (41.67/14.83)	.....................................................................SPPSVGDT.EKMYQSQ.IVPCTCIVVEEEVDPsaeqtisadrldsekvtptgpdsnvlprDDEAQ.GDSIQK.LERNV..AD
  705-  785 (95.48/43.84)	DKTVlpAPQKPIKSIFDLD..FDE......DD.....DP................LqSIIRDLRPPTVDLEAANGD.....VKSMmTTSANVITATSGI.T............................DG.AP.VHTDGMdLDQD.....
 1092- 1186 (164.09/80.84)	NGKV..TSQRQISNISSSNNSSDN......EDKERGSDT................L.SLSDDINASQTHSPASNEDEHDDSFQSG.TTTFDSIVADEDVDG............................DGDAD.GDGDGV.LENDYENSD
 1373- 1459 (71.21/30.76)	...............SSSSSSSDNsdipsdSDEEDNSSStneadniqvakhktniI.NIETDIKASASKDAAKQEDEE..........PCES.....................................SSDNDnGDDDDF.VKEDFANLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.90|      38|     287|      93|     130|       2
---------------------------------------------------------------------------
   93-  130 (67.12/38.83)	PAPSQ.PLTAGESAVVVVPSQQ.SSSPLAPPQLPI....NLQKN
  381-  424 (51.78/28.18)	PTPSLfPFEERRKALEEAGKQQiEISVLVPPSTTTsslgNEQSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.74|      20|      57|    1461|    1494|       3
---------------------------------------------------------------------------
 1461- 1480 (37.88/36.58)	NIEIDTVNNLPLHNN.......GLLPS
 1519- 1545 (32.86/ 8.32)	NENCDDVNNLYYNNNnldviknSLVPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     271.13|      83|     265|     224|     341|       4
---------------------------------------------------------------------------
  249-  332 (138.71/111.56)	QRPKATLLNRNEVMGQQSRYATKINCAPYKDGKAQAVIPTDAAEIlSLSNSSMSSILSGDVTVGNSHSKSMPPRPNNTSELTFA
  830-  884 (81.69/36.89)	.........................CVPNINGNWDGV..ETASE..SISSLELYAVTDGADVVPKYGSLTCERIPKDLSGLKFA
 1194- 1234 (50.73/13.38)	QRPVACGTSSNHIVLTIKKTPSKIN.SP...NSISAVSPITGSEI.......................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.76|      14|     265|     224|     247|       5
---------------------------------------------------------------------------
  230-  247 (20.41/27.30)	VPARNKKlkkdKRRRERE
 1064- 1077 (25.35/ 7.87)	VIERNRK....KRRKTRE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.86|      19|      26|     986|    1004|       6
---------------------------------------------------------------------------
  986- 1004 (34.73/22.90)	DDEIHNNSSFRGPSE.NENS
 1013- 1032 (29.13/17.75)	DDDLPLEVGANGEMEfRENS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.63|      50|      61|     462|     521|       7
---------------------------------------------------------------------------
  465-  518 (76.02/48.77)	SSLSQQIF.FGSGVKKV.KTTKELFNELQSRKLSNVVQ.SVNNL..SNAssdrDREEAL
 1288- 1342 (64.61/29.97)	SLLSSQTYcIGSYRRRLhRLRRRRLRIEKSAKLRNTIDiELNHLfiSNA....ERSAPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.60|      24|      25|     553|     577|      10
---------------------------------------------------------------------------
  553-  577 (36.39/24.52)	DADKfSNQNEDIGNTDSDTIT.SEPS
  579-  603 (34.21/17.69)	DSQK.SRGNKATSSLESNSNSlQTPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.37|      18|      18|     926|     943|      11
---------------------------------------------------------------------------
  926-  943 (30.75/21.52)	QPKSPEISCKLEESESEL
  947-  964 (29.62/20.36)	QLKNENVSIISKSSPSPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.31|      17|      18|    1235|    1251|      15
---------------------------------------------------------------------------
 1235- 1251 (30.29/19.75)	VPGSAKKSYFINMIDPN
 1256- 1272 (27.02/16.75)	VQSSSKENEAIVEAEPQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25236 with Med26 domain of Kingdom Metazoa
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