<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25219

Description "Uncharacterized protein, isoform A"
SequenceMDFMMANTGAGGGVDTQAQLMQTAAAAAAVAATNAAAAPVQNAAAVAAAAQLQQQQQVQQAILQVQQQQTQQAVAAAAAAVTQQLQQQQQAVAQQQQQQQQQQQQQQQQQQQQVQQQQQVVAQQQPQPNTNGNAGGAQNGSNGSTETRTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYIDPLNPQAPSKGQSLGYGFVNYVRPQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGLPKTMTQQELESIFAPFGAIITSRILQNAGNDTQTKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNTPGSTSKIIQPQLPAFLNPQLVRRIGGAMHTPVNKGLARFSPMAGDMLDVMLPNGLGAAAAAATTLASGPGGAYPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQCKGYGFVSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNKAK
Length483
PositionTail
OrganismDrosophila willistoni (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.06
Grand average of hydropathy-0.311
Instability index47.92
Isoelectric point9.07
Molecular weight51465.35
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
Cajal body	GO:0015030	IEA:EnsemblMetazoa
ribonucleoprotein complex	GO:1990904	IEA:InterPro

GO - Biological Function
poly(U) RNA binding	GO:0008266	IEA:EnsemblMetazoa

GO - Biological Process
central nervous system development	GO:0007417	IEA:EnsemblMetazoa
negative regulation of mRNA 3'-end processing	GO:0031441	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25219
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     121.99|      27|      28|     212|     238|       3
---------------------------------------------------------------------------
  211-  237 (42.65/27.76)	V.............................RP.QDAEQAVNV.LNGL..RLQNKT..IKVSF
  238-  268 (25.37/13.48)	A.............................RPsSDAIKGANLyVSGLpkTMTQQE..LESIF
  269-  326 (21.31/10.12)	ApfgaiitsrilqnagndtqtkgvgfirfdKR.EEATRAIIA.LNGT..TPSSCTdpIVVKF
  455-  477 (32.66/19.51)	..................................EAAMAIRA.LNGY..TMGNRV..LQVSF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.61|      26|     151|     270|     295|       4
---------------------------------------------------------------------------
  173-  208 (27.73/15.69)	..GEIESVKLIRDksqvyidplnpqAPSKGQSLGYGFV
  270-  295 (44.37/29.73)	PFGAIITSRILQN............AGNDTQTKGVGFI
  424-  448 (47.51/32.39)	PFGAVQSVKIVKD............PTTN.QCKGYGFV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.63|      41|     251|     128|     169|       6
---------------------------------------------------------------------------
  128-  169 (67.62/41.15)	PNTNGNAGGAQNGSN.GSTETRTNLIVNYLPQTmTEDEIRSLF
  381-  422 (68.01/37.09)	PNGLGAAAAAATTLAsGPGGAYPIFIYNLAPET.EEAALWQLF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25219 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QQQVVAQQQPQPNTNGNAGGAQNGSNGSTETRTNLIVNYL
117
156










Molecular Recognition Features






MoRF SequenceStartStop




NANANA