<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25219

Description "Uncharacterized protein, isoform A"
SequenceMDFMMANTGAGGGVDTQAQLMQTAAAAAAVAATNAAAAPVQNAAAVAAAAQLQQQQQVQQAILQVQQQQTQQAVAAAAAAVTQQLQQQQQAVAQQQQQQQQQQQQQQQQQQQQVQQQQQVVAQQQPQPNTNGNAGGAQNGSNGSTETRTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYIDPLNPQAPSKGQSLGYGFVNYVRPQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGLPKTMTQQELESIFAPFGAIITSRILQNAGNDTQTKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNTPGSTSKIIQPQLPAFLNPQLVRRIGGAMHTPVNKGLARFSPMAGDMLDVMLPNGLGAAAAAATTLASGPGGAYPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQCKGYGFVSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNKAK
Length483
PositionTail
OrganismDrosophila willistoni (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.06
Grand average of hydropathy-0.311
Instability index47.92
Isoelectric point9.07
Molecular weight51465.35
Publications
PubMed=17994087

Function

Annotated function
GO - Cellular Component
Cajal body	GO:0015030	IEA:EnsemblMetazoa
ribonucleoprotein complex	GO:1990904	IEA:InterPro
GO - Biological Function
poly(U) RNA binding	GO:0008266	IEA:EnsemblMetazoa
GO - Biological Process
central nervous system development	GO:0007417	IEA:EnsemblMetazoa
negative regulation of mRNA 3'-end processing	GO:0031441	IEA:EnsemblMetazoa

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP25219
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     121.99|      27|      28|     212|     238|       3
---------------------------------------------------------------------------
  211-  237 (42.65/27.76)	V.............................RP.QDAEQAVNV.LNGL..RLQNKT..IKVSF
  238-  268 (25.37/13.48)	A.............................RPsSDAIKGANLyVSGLpkTMTQQE..LESIF
  269-  326 (21.31/10.12)	ApfgaiitsrilqnagndtqtkgvgfirfdKR.EEATRAIIA.LNGT..TPSSCTdpIVVKF
  455-  477 (32.66/19.51)	..................................EAAMAIRA.LNGY..TMGNRV..LQVSF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.61|      26|     151|     270|     295|       4
---------------------------------------------------------------------------
  173-  208 (27.73/15.69)	..GEIESVKLIRDksqvyidplnpqAPSKGQSLGYGFV
  270-  295 (44.37/29.73)	PFGAIITSRILQN............AGNDTQTKGVGFI
  424-  448 (47.51/32.39)	PFGAVQSVKIVKD............PTTN.QCKGYGFV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.63|      41|     251|     128|     169|       6
---------------------------------------------------------------------------
  128-  169 (67.62/41.15)	PNTNGNAGGAQNGSN.GSTETRTNLIVNYLPQTmTEDEIRSLF
  381-  422 (68.01/37.09)	PNGLGAAAAAATTLAsGPGGAYPIFIYNLAPET.EEAALWQLF
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP25219 with Med15 domain of Kingdom Metazoa

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