<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25214

Description Uncharacterized protein
SequenceMMEQQQSDPSQQHGLGGLAKSLGNQRHGNLSAPSSNQESLADVVFVIESSAINGAYINELKTNYILPTLEHFTQGSIDEREYLIADRFATLYGVVIYKSASNLLEPLCATYGPFVQPQKVMETIERLPLVGGGMESCAHMAEGFAAAHGCFEDISEQRQRMLMEQPNVQRHCICIANSPPYQMPVMESWKYMGKSCEQLASLFHERKINLSIIAPRKMPVLFKLFMKADGDQPITSKNYAKNLRHLVLLKGYSLKERAPSPNSMVAPNPTQQQQQNPSGQQQTGQNMPMDTSPAQQQQQQQQQQMMQQQNQFVPQNPNFQQNRWMYANQPGQPRPPFMQGPVQGGGGVGVGVGVGVGMPMQPQQQQQQQQQQQQQQNPNSALISRINAPPNQVNSLQQQQQQQRLQMLNQQQQFQLQQQLAQQQQQQQQQQQQQQQQQVNANANNNMMPVVSNAGNMPNPQVGPQQQTNPQQQQQQQQQQQQQVNPQQQQQQGNPQEQASLREKIWTGVLEWSEKAKNDQQKIPHTLQCTVCTNIKDGEPEIKAENWPPKLLMQLMPKHLVGNIGGQFLKDSKMVVFRPTPGEALDSLAKMMTSGFAGCVHFSSLPNTPACDIKVLILLYTPDRNAFLGFIPNNQTMFVERLRKVIQQKQSHGNMQQQQQQQQQQILQQQQQQQQQQQQQQGKSPMELQQQQQQQQQQQMQQDNSQQQQQQQQHYNQYQLNMQMGGGGPGGPGGMQQAQQMQQMNMMQQQQQQQQQQRMPLGVPNPNLQQQLQQVPPNVAAMQQQQQQQRMVRPMMSNNPGLRQLLQHQTTPGNQFRPQMGGQNPNQMGGGAPMVGNRNFDDGSYEFI
Length848
PositionUnknown
OrganismDrosophila willistoni (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.05
Grand average of hydropathy-0.982
Instability index72.16
Isoelectric point8.85
Molecular weight96163.11
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25214
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.50|      29|      58|     330|     387|       1
---------------------------------------------------------------------------
  283-  332 (41.28/ 8.28)	TGQNMPMDtsPAQQQQQQQQQQmmqQQnqfvpQNP........NfqqnrwmyanqPGQ
  354-  392 (56.21/ 8.37)	VGVGMPMQ..PQQQQQQQQQQQ...QQ.....QNPnsalisriN.........apPNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     160.73|      32|      32|     647|     678|       2
---------------------------------------------------------------------------
  655-  687 (62.68/13.33)	MQQQQQQQQQQILQQQQQQQQQQQ...qQQGK...........SP...ME
  688-  734 (50.78/ 8.93)	LQQQQQQQQQQQMQQDNSQQQQQQqqhyNQYQlnmqmggggpgGP...GG
  735-  763 (47.27/ 7.64)	MQQAQQMQQMNMMQQQQQQQQQQR.....................mplGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     253.10|      46|      48|     407|     454|       3
---------------------------------------------------------------------------
  409-  453 (85.72/18.33)	.N....QQQQFQLQ.QQLAQQQQQQQQQQQ...QQQQQQVNANANNNMMPVVSN
  458-  494 (47.04/ 6.47)	PNpqvgPQQQTNPQ.Q...QQQQQQQQQQQvnpQQQQQQGN.............
  764-  798 (64.27/ 8.53)	PN........PNLQ.QQLQQVPPNVAAMQQ...QQQQQRM....VRPMM...SN
  799-  837 (56.08/ 7.22)	...........NPGlRQLLQHQTTPGNQFR...PQMGGQ.NPNQMGGGAPMVGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.90|      17|      32|     180|     198|       4
---------------------------------------------------------------------------
  180-  198 (32.36/29.06)	PYQMPVMesWK.YMGKSCEQ
  215-  232 (28.55/18.14)	PRKMPVL..FKlFMKADGDQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.56|       9|     378|     338|     349|       6
---------------------------------------------------------------------------
  338-  349 (15.00/11.51)	MQgpvQGGGGVG
  722-  730 (21.56/ 8.00)	MQ...MGGGGPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.93|      25|      39|      98|     122|       7
---------------------------------------------------------------------------
   98-  122 (45.42/32.23)	KSASNLLEPLCATYGPF..VQPQK...VME
  135-  164 (36.51/24.27)	ESCAHMAEGFAAAHGCFedISEQRqrmLME
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.09|      14|     355|     240|     272|      10
---------------------------------------------------------------------------
  259-  272 (26.75/10.56)	PSPNSMVAPNPTQQ
  622-  635 (26.34/ 6.37)	PDRNAFLGFIPNNQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25214 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QQQQQQQQQQVNANANNNMMPVVSNAGNMPNPQVGPQQQTNPQQQQQQQQQQQQQVNPQQQQQQGNPQEQASLREKI
2) RAPSPNSMVAPNPTQQQQQNPSGQQQTGQNMPMDTSPAQQQQQQQQQQMMQQQNQFVPQNPNFQQNRWMYANQPGQPRPPFMQGPVQGGGGVGVGVGVGVGMPMQPQQQQQQQQQQQQQQNPNSALISRINAPPNQVNSLQQQQQQQR
3) RLRKVIQQKQSHGNMQQQQQQQQQQILQQQQQQQQQQQQQQGKSPMELQQQQQQQQQQQMQQDNSQQQQQQQQHYNQYQLNMQMGGGGPGGPGGMQQAQQMQQMNMMQQQQQQQQQQRMPLGVPNPNLQQQLQQVPPNVAAMQQQQQQQRMVRPMMSNNPGLRQLLQHQTTPGNQFRPQMGGQNPNQMGGGAPMVGNRNFDDGSYEFI
429
257
641
505
404
848










Molecular Recognition Features






MoRF SequenceStartStop




1) YNQYQL
715
720