<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25209

Description Uncharacterized protein
SequenceMDLDTQIIDSVNNFLKVDSIDEAFLSVIVFKPNGEQTKAQSFTNDFVTAFGQVPQENRDQVLRVYLLRTASASHCHMKVLMNALVKLVDAHHITARALCDKVLSCEKLEYEHKIFWIESFRLIKKVIVHVDYKGVREIMKVCRDKTQWFPLNVNVAYLPQLLAVEEIIRFIFDRNNCLLPAYFIANEIMRPFPYHWKLNKLMTDFVEEFRSTAQMVSIIGHAHMLPIVEHFGYADHMMNSWRLDHNTLKFTFKGSLPYEPELLEEQRLLLRYVLEQPYSREMVSQMLNLQKHQKQRYNALEEQLVNLIIHAMEMTEANDTLAGSGFNACDEQITPYEWVWLHLSSQLIYFVLFQFVSFMHIVLSLHEKLSKLELRKGRDQLMWILLQFISGSIQKNPITNFLPVFRLFDLLYPEQEPLKLPDINKSSMVRHMAPICVWIHLMKKARVENMNITRPLPIALKNHYDFLQHLVTPNTLMNMSLGSDFRIILICNAYSTNQEYFGRPMSILLDALNGNSKSANGAQIPAVTFSVAVLDSLTVHSKMSLIHSFVTQMLKQAQNKSQVPAAALLETYARLLVYTEIESLGIKGFLSQLMPTVFKNHAWAMLHTLMEMFSYRLHHVPTHYRVQLLSLLHSLSSLPQTNKMQLNLCFESTALRLITSISSAEFQPQFSRYFNEKSPGAVASNESEELNRVLILTLARSMHVHGGGDELQGWCKDFLSNIMQHTPHSWPLQSLTCFPPALNEYFAQNNQPSENKQVLKKSVEEEYRMWTSMSNENDIIAHFLRPNANPLFLCLLFKIIWETENISPVAYKILEQISARALSTLLRKFCDYLVVEVASFSDGRDFIHKCVDTINNMIWKFNVVTIDRVVLCLALRTHEGNEAQVCFLIIQLLLLKASELRNRVQEFCKDNNPDHWKQSNWQDKHLSFHQKYPEKFALDESASQIPLPVYFSNVCLRFLPVLDVVVHRFIELTIPNVHQILGYILDHLSILYKFHDRPITYLYNTLHYYERILRDRPSLKKKLVSTITSAFSEIRPPNWSITEPYKVFLQNQDLLWTPELGYYMNLIRRLADTISGKNVFYTTDWRFNEFPNAPAHALYVTCVELLGLPVAPSLVANNIIDVIVNGYAVIPQKEIHSYINAVGIVLAALPEPYWSGIYDRLQDMLNTPNMLKWTYRFNAFDMFNFKTVREAMLEKSYAVVLAVAHAVFHHMGVFKLAAMVRYIKEKLKPCVRTEQQLLYLCHVFGPFLQRIEMEKPNAVAGIGILLYEILEVVDKQHGPKPLQYMDQICDFLYHIKYIYVGNIIRNESEAIIKRLRPQLQMRLRFITHLNVEDIHTEKSVENNQQQQQQLQQQHQQQQQQQQQQQQQQQQQQQQLNQQQQQQMFMQHMQQQQHMQNIGMRHN
Length1402
PositionTail
OrganismDrosophila willistoni (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.10
Grand average of hydropathy-0.149
Instability index44.89
Isoelectric point7.65
Molecular weight163616.81
Publications
PubMed=17994087

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP25209
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.56|      15|      16|    1351|    1365|       1
---------------------------------------------------------------------------
 1351- 1365 (33.61/17.81)	QQQHQQQQ..QQQQQQQ
 1367- 1383 (27.30/13.17)	QQQQQQQQlnQQQQQQM
 1384- 1395 (19.64/ 7.54)	FMQHMQQQ..QHMQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.65|      14|      20|     257|     276|       2
---------------------------------------------------------------------------
  257-  271 (20.60/24.56)	PYEPELLeEQRLLLR
  277-  290 (26.04/10.22)	PYSREMV.SQMLNLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.78|      18|      20|    1154|    1172|       4
---------------------------------------------------------------------------
 1154- 1172 (30.27/25.16)	WSGIYDRLqDMLN....TPNMLK
 1173- 1194 (29.51/18.80)	WTYRFNAF.DMFNfktvREAMLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.60|      14|      20|     202|     215|       5
---------------------------------------------------------------------------
  202-  215 (25.17/17.28)	MTDFVEEFRSTAQM
  224-  237 (27.43/19.55)	MLPIVEHFGYADHM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.02|      15|      18|    1080|    1097|       6
---------------------------------------------------------------------------
 1080- 1094 (31.09/26.20)	FYTTDWRFNEFPNAP
 1098- 1112 (26.93/12.33)	LYVTCVELLGLPVAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.09|      14|      19|     873|     886|      12
---------------------------------------------------------------------------
  873-  886 (25.31/14.66)	LALRTHE.GNEAQ.VC
  893-  908 (15.78/ 6.73)	LLLKASElRNRVQeFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.50|      36|      75|     652|     692|      13
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  652-  692 (55.74/48.71)	STALRLITSissaeFQPQFSRYFNEKS.PG...AVASNESEELNR
  729-  768 (56.76/38.09)	SWPLQSLTC.....FPPALNEYFAQNNqPSenkQVLKKSVEEEYR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.39|      15|      28|    1255|    1269|      17
---------------------------------------------------------------------------
 1255- 1269 (25.94/16.27)	KP.NAVAGIGILLYEI
 1280- 1295 (26.45/16.74)	KPlQYMDQICDFLYHI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.51|      28|      53|     383|     411|      18
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  383-  411 (45.81/34.85)	WILLqFISGSIQKNPITNFLPVF..RLFDLL
  438-  467 (47.70/31.27)	WIHL.MKKARVENMNITRPLPIAlkNHYDFL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP25209 with Med23 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) TEKSVENNQQQQQQLQQQHQQQQQQQQQQQQQQQQQQQQLNQQQQQQMFMQHMQQQQHMQNIGMRHN
1336
1402

Molecular Recognition Features

MoRF SequenceStartStop
NANANA