<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25207

Description "Uncharacterized protein, isoform B"
SequenceMNQNQIQQLTSHLSQALDQNYDVVNMEAVLSVICALEGTTITKEQLEATRLAKYINQLRRRTKNDQLARRAKSLLKKWREMVGIHQQTTIEPQPQPLAHLSFKPIVGTHFPETESNTVEVMVNSTQYTSQSSPPSSQRVNTDLHPNVDSSEPHHINFSSLINNNINTDNRDDSLAIISKSIKHPRTIESKSQKSATFINEHSSNSVSSVMVANEKLNETSIVIDIVSDSDENDSQSQPVNNHQKLATVSSSLALPAVYPRPKKIKKDKKRKEKDGRDKPSQFYFNDGVPQQLTNANRSNLNRIPVKEGRMSKTNPTDPEILSLSNSSMSSILSGDAFSGSSQNRPRTTAAELTFAGRFNSVSRPDTSNYVNAVQANGQKKICQVNDPPSLDLTIPQMYDDFINNDSSTSCSRLSPYEELEAKPGQNNSKASTEATPKKRGRKKGSKGVDSLIAKESSLSQQILFGSGVKKVKTTKELFNDMQSRKLSISFNRGDSLPAVANKITNTTTLRNLESRSLIARPTSSCSETSIHSPHTLEAYSTNVSQAGTEKLSNILEGILEPGNTDSDTITSEPSRDSMKSRNIKRMNSLDSNSNSLQTTSVLTSSKDYNDVTTQLMHMVHNLNSPLSVNETEKLYQAQIVPCTCIVVEDIPKESSAHDNIDHSDMEADSINKATCDIETVRDKKHSEQPSLKTDNCDVEEAPLLISQKPIKSIFDLDFDDEDDPLQSIIKNISLPESNLKQDPDDYIKSSFTVRSLTEENKDLKVVSDSYLDQEASNIVLEPISVYTVYEDPDCVAKQRFDVQTNDVTNFHINALHNYYIPNINGNWNSIDSSIVLTTTVMKFLQSLESYTVTDGADVVPKYGSLTYERIRKDLSYLKFDRNWKSKSFKSFIPPFLGVAKCLPTCRLAAKRLKDKTKALSTTKSVETIIKLEEPEIIINYFEKNKGSPSPLRVEVDANGNSGENQAQTQSSEDDPLMNNNATLSFNLLKLVNNNEGRKSIVDDQVNSKPTIDGLDNRKGIRCSSDSSCSNSSLQLTQDSINEKLRNQRNLSLTSEQSQSERNVERNRKKRRKARHAESNDGIDFGNNIEIANTSIDEKPLIKRIKIAINGNVATQRQISGISSSNNSSDDEHDDEVGGEARSEVSDPEVGYNTSGYSQIGLAASDDEQESNRSHSTTIDSIAADDDGHLENEYENSNDEEYAIVQRPMVGVANNHIVLTIKKTPSKMNSPVNSISAISPNVGQASASVAGTLEAHTSKNAHFATTNTDSKIEYPETEIIGEYQRKFSLAPMVFCTDELHRLDPDRPFLTSNTCQNNLKTSYQYCRRRRRLRYRRPRDLICPKETIDIELKHLFNNVTRSTQMLLKPHRKLFFANELCRQDGAGRKERIVNYSSSSSSSSGSCTSNDEDDSDPEEKSKRERKRYSALSEDTEKCQIAVSKTQKLKNETDPNIAAKNINDQEDLYLYSDSDESLNTGEFGNQHNELNDPKLNKQDELPLHNNGMLPSFNFIYNDQQLKASANEVNEKAFEKPSLKLLQIQNCDDVNVCYNNINISVIKSHSLGSVKPINDDDNGKQCVINNLTSESLEKAKNCNPIYTDVSSELMLSQPAIEYRTGIRAVVDDAPSKYGVNTTQIQQFKEWHEVLQLQSYNNEPLIVLPYVVLE
Length1662
PositionUnknown
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.763
Instability index47.66
Isoelectric point5.68
Molecular weight185689.84
Publications
PubMed=17994087
PubMed=18057021

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25207
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     772.34|     221|     237|      97|     333|       1
---------------------------------------------------------------------------
   97-  263 (206.42/122.93)	........................................................................................LAHLSFKPIVGTHFPET.......ESN....TV.....EVMVNSTQYTSQSSPPSSQRVNTDLHPN.....VDSSEPHHINFSSLINNNintDNRDDSLAIISKSIKHPRTIESKSQKSATFINEHSSNSVSSVMVA....NEKL.NE......TSIVI.DIVSDS......DENDSQSQPVNNHQKlATVSSSLAlpavyPRPKK
  264-  440 (210.87/122.44)	IKKDKKRKEKDGRDKPS...QFYFNDGV.....PQQLTNANRS.....NLNR...IPVKEGRMskTNPTdpeilSLSNSSMSSILS...................gdafsgsSQNrprtTA.....AELTFAGRFNSVSRPDTSNYVNA.VQANgqkkiCQVNDPPSLDL...............................TIPQMYDDFINNDSSTSCSR.LSP....YEEL.E................AKP......GQNNSKASTEAT.................PKKRG
  441-  684 (263.04/138.12)	RKKGSKGVDSLIAKESSlsqQILFGSGVkkvktTKELFNDMQSrklsiSFNRgdsLPAVANKI..TNTT.....TLRNLESRSLIArpTSSCSETSIHSPHTLEA.......YST....NVsqagtEKLSNILEGILEPGNTDSDTITSE..PS.....RDSMKSRNIKRMNSLDSN...SNSLQTTSVLTSS.KDYNDVTTQLMHMVHNLNSPLSVN......E....TEKL.YQaqivpcTCIVVeDIPKESsahdniDHSDMEADSINK....ATCDIETV......RDKK
  961- 1069 (92.02/40.03)	..........................................................................................................................................SGENQAQTQSSEDDPL.....MNNNATLSFNLLKLVNNN...EGRK...SIVDDQVNSKPTIDGLDNRKGIRCSSDSSCSNSSLQLTqdsiNEKLrNQ......RNLSL.....TS......EQSQSERNVERNRKK...................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     129.67|      33|      35|     691|     725|       2
---------------------------------------------------------------------------
  693-  725 (57.16/36.35)	TDNCDVEEAPLLISQKP...IKSIFDL.DFDDEDDPL
  730-  763 (34.00/16.50)	.KNISLPESNL..KQDPddyIKSSFTVrSLTEENKDL
  767-  793 (38.52/16.89)	SDSYLDQEASNIV.LEP...I.SVYTV..YEDPD...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.84|      25|      29|    1293|    1321|       3
---------------------------------------------------------------------------
 1293- 1318 (43.26/32.00)	FCTDElHRLDPDRP...FLTSNTCQNNLK
 1323- 1350 (41.58/18.78)	YCRRR.RRLRYRRPrdlICPKETIDIELK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.83|      22|      33|    1119|    1149|       4
---------------------------------------------------------------------------
 1119- 1142 (35.21/17.98)	SGISSSN.NS......SDDEHDDEvgGEARS
 1154- 1169 (15.25/ 6.84)	SGYSQIGlAA......SDDEQE.........
 1391- 1416 (24.37/ 7.16)	..YSSSS.SSssgsctSNDEDDSD..PEEKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.70|      23|      31|    1202|    1226|       8
---------------------------------------------------------------------------
 1202- 1226 (35.32/26.97)	AIvqRPMVGVANNHIVLTIKKTPSK
 1236- 1258 (38.38/23.02)	AI..SPNVGQASASVAGTLEAHTSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.82|      12|      32|    1456|    1467|       9
---------------------------------------------------------------------------
 1456- 1467 (21.31/12.46)	INDQEDLYLYSD
 1489- 1500 (21.51/12.66)	LNKQDELPLHNN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25207 with Med26 domain of Kingdom Metazoa
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