<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25206

Description "Embryonic lethal, abnormal vision"
SequenceMDFMMANTGATGVDTQAQLMQSAAAAAAVAATNAAAPVQNAAAVAAAAQLQQQQQQVQQAILQVQQQQTQQAVAAAAAAVTQQLQQQQQAVVQQAVVQQQQQQQQQQQQQQQVVQQQQVQQVQQAVANTNGNSGGAQNGSNGSTETRTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYIDPLNPQAPSKGQSLGYGFVNYVRPQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGLPKTMTQQELEAIFAPFGAIITSRILQNAGNDTQTKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNTPGSTSKIIQPQLPAFLNPQLVRRIGGAMHTPVNKGLARFSPMAGDMLDVMLPNGLGAAAAAATTLASGPGGAYPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQCKGYGFVSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNKAK
Length482
PositionTail
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.06
Grand average of hydropathy-0.240
Instability index44.87
Isoelectric point9.07
Molecular weight51355.37
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
Cajal body	GO:0015030	IEA:EnsemblMetazoa
ribonucleoprotein complex	GO:1990904	IEA:InterPro

GO - Biological Function
poly(U) RNA binding	GO:0008266	IEA:EnsemblMetazoa

GO - Biological Process
central nervous system development	GO:0007417	IEA:EnsemblMetazoa
negative regulation of mRNA 3'-end processing	GO:0031441	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25206
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     118.58|      32|      54|      23|      74|       1
---------------------------------------------------------------------------
   16-   56 (21.43/21.52)	.........QAQLMQ..SaaaaaavaatnaaapvqnAAAVAAAAQLQQQQQQ
   57-   90 (53.91/20.93)	VQQAILQVQQQQTQQavA..................AAAAAVTQQLQQQQQA
   92-  112 (43.24/12.61)	VQQAVVQQQQQQQQQ...............................QQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     267.50|      54|      54|     227|     280|       2
---------------------------------------------------------------------------
  156-  191 (46.68/25.90)	PQTMTE.DEIRSLFSSVGEI..............eSVK..LIRDKS......QVYIDPL
  193-  225 (43.70/23.80)	PQAPSKgQSLGYGF........................VNYVRP.QDAEQAVNV.LNGL
  227-  254 (27.66/12.51)	..............................LQNK.TIKVSFARPSSDAIKGANLYVSGL
  255-  309 (77.62/47.69)	PKTMTQ.QELEAIFAPFGAIITSRILQnagNDTQ.TKGVGFIR..FDKREEATRAIIAL
  410-  462 (71.85/43.62)	PET.EE.AALWQLFGPFGAVQSVKIVKdptTN.Q.CKGYGFVS..MTNYDEAAMAIRAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.25|      13|     360|      23|      37|       3
---------------------------------------------------------------------------
   23-   37 (17.98/14.45)	AAAAAavAATNAAAP
  385-  397 (23.28/12.35)	AAAAA..ATTLASGP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25206 with Med15 domain of Kingdom Metazoa
Unable to open file!