<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25206

Description "Embryonic lethal, abnormal vision"
SequenceMDFMMANTGATGVDTQAQLMQSAAAAAAVAATNAAAPVQNAAAVAAAAQLQQQQQQVQQAILQVQQQQTQQAVAAAAAAVTQQLQQQQQAVVQQAVVQQQQQQQQQQQQQQQVVQQQQVQQVQQAVANTNGNSGGAQNGSNGSTETRTNLIVNYLPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYIDPLNPQAPSKGQSLGYGFVNYVRPQDAEQAVNVLNGLRLQNKTIKVSFARPSSDAIKGANLYVSGLPKTMTQQELEAIFAPFGAIITSRILQNAGNDTQTKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNTPGSTSKIIQPQLPAFLNPQLVRRIGGAMHTPVNKGLARFSPMAGDMLDVMLPNGLGAAAAAATTLASGPGGAYPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQCKGYGFVSMTNYDEAAMAIRALNGYTMGNRVLQVSFKTNKAK
Length482
PositionTail
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.06
Grand average of hydropathy-0.240
Instability index44.87
Isoelectric point9.07
Molecular weight51355.37
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
Cajal body	GO:0015030	IEA:EnsemblMetazoa
ribonucleoprotein complex	GO:1990904	IEA:InterPro

GO - Biological Function
poly(U) RNA binding	GO:0008266	IEA:EnsemblMetazoa

GO - Biological Process
central nervous system development	GO:0007417	IEA:EnsemblMetazoa
negative regulation of mRNA 3'-end processing	GO:0031441	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25206
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     118.58|      32|      54|      23|      74|       1
---------------------------------------------------------------------------
   16-   56 (21.43/21.52)	.........QAQLMQ..SaaaaaavaatnaaapvqnAAAVAAAAQLQQQQQQ
   57-   90 (53.91/20.93)	VQQAILQVQQQQTQQavA..................AAAAAVTQQLQQQQQA
   92-  112 (43.24/12.61)	VQQAVVQQQQQQQQQ...............................QQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     267.50|      54|      54|     227|     280|       2
---------------------------------------------------------------------------
  156-  191 (46.68/25.90)	PQTMTE.DEIRSLFSSVGEI..............eSVK..LIRDKS......QVYIDPL
  193-  225 (43.70/23.80)	PQAPSKgQSLGYGF........................VNYVRP.QDAEQAVNV.LNGL
  227-  254 (27.66/12.51)	..............................LQNK.TIKVSFARPSSDAIKGANLYVSGL
  255-  309 (77.62/47.69)	PKTMTQ.QELEAIFAPFGAIITSRILQnagNDTQ.TKGVGFIR..FDKREEATRAIIAL
  410-  462 (71.85/43.62)	PET.EE.AALWQLFGPFGAVQSVKIVKdptTN.Q.CKGYGFVS..MTNYDEAAMAIRAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.25|      13|     360|      23|      37|       3
---------------------------------------------------------------------------
   23-   37 (17.98/14.45)	AAAAAavAATNAAAP
  385-  397 (23.28/12.35)	AAAAA..ATTLASGP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25206 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AVANTNGNSGGAQNGSNGSTETRTNLIVNYL
125
155










Molecular Recognition Features






MoRF SequenceStartStop




NANANA