<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25203

Description Uncharacterized protein
SequenceMFNSNIPAAALLSIEGSGLGAHTPKTPEILNSLIAMTNPLDNFNFNGSGNCSAASTPVVTIRNFCGNANGQSHSQDSSHSSCSASPLDSPAGTATTPSVQQTCSQLIKAGLKLSIQSKRKLSTCDSSSGSEQPNSKCSRRDEDCEESSDEDSETKSVPKGLTPEDEDRRRRRRERNKIAATKCRMKKRERTQNLIKESEVLDTQNVDLKNQVRTLETDRRRLLEMLQAHSPGCVKRGGCQLPSKLLQSPATKYLAELELEGLLNGDAAGSAANTPTQRQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQRMQSIPSMSTFKFGSKTPAVMAAAVAAAQAQQQQQQQQQQLQQQQLPNGYCKPSPSPQEFEHAGYLSSPTQEALCLPQQLQQQQQQQQQQQSSLNPASNNNSNNNADNNGNLVVSQQVSDYVPNCEGLSLGLGLSAVAVAITTPTNSSSNTSLSSLSSLSSSNNTSSNHSSSNTLAAAAAATTSLPSATTLPPATTPTSAIEFVKNELVDSQSPYTTALSAERFLFESSDGFPDIKHAVSVHPSSILNNMTSVASLAVHNNNNSHLMDFHNGLPHGGGVGVGIMTPVYEEEQLLIMKNSCFPNDLLSQLGDETDFVDLDTGAAAFMHNGGCLA
Length641
PositionTail
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.03
Grand average of hydropathy-0.689
Instability index68.18
Isoelectric point5.73
Molecular weight68951.14
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA binding	GO:0003677	IEA:InterPro
DNA-binding transcription factor activity	GO:0003700	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25203
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     186.17|      43|      48|     288|     330|       1
---------------------------------------------------------------------------
  294-  330 (63.76/22.44)	......QQQQQQQQQQQQ...................QQQRMQSIPSMSTFK....FGSKTPA..VMA
  337-  385 (69.51/25.04)	QAQQQQQQQQQQLQQQQL...................PNGYCKPSPSPQEFEhagyLSSPTQEalCLP
  386-  445 (52.90/17.52)	QQLQQQQQQQQQQQSSLNpasnnnsnnnadnngnlvvSQQVSDYVPNCEGLS....LGLGLSA..V..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.81|      12|      15|     454|     467|       2
---------------------------------------------------------------------------
  454-  467 (15.73/12.86)	NSSSNTslSSLSSL
  472-  483 (22.08/11.45)	NTSSNH..SSSNTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.95|      33|      48|     136|     183|       3
---------------------------------------------------------------------------
  136-  170 (53.59/63.83)	KCSRRDEDCEESSDEDseTKSVP..KGLTPEDEDRRR
  187-  221 (49.36/25.87)	KRERTQNLIKESEVLD..TQNVDlkNQVRTLETDRRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.52|      11|      18|     501|     511|       4
---------------------------------------------------------------------------
  501-  511 (20.86/14.98)	PATTPTSAIEF
  522-  532 (20.67/14.77)	PYTTALSAERF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.29|      30|      39|      54|      85|       5
---------------------------------------------------------------------------
   54-   85 (51.25/30.12)	ASTPVVtiRNFCGN..ANGQSHSQDSSH..SSCSAS
   94-  127 (41.03/18.69)	ATTPSV..QQTCSQliKAGLKLSIQSKRklSTCDSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.43|      31|      56|     548|     580|       6
---------------------------------------------------------------------------
  548-  580 (48.89/34.56)	SVHPSSILNNMTSVASLAVHNNNNSHLMdfHNG
  607-  637 (54.54/32.08)	SCFPNDLLSQLGDETDFVDLDTGAAAFM..HNG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25203 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ELELEGLLNGDAAGSAANTPTQRQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQRMQSIPSMSTFKFGSKTPAVMAAAVAAAQ
2) KLSTCDSSSGSEQPNSKCSRRDEDCEESSDEDSETKSVPKGLTPEDEDRRRRRRERNKIAATKCRMKKRERTQNLIKESEVLDTQNVDLKNQVRTLETDRRRLLEMLQAHSPGCVKRGGCQL
3) QQQQQLQQQQLPNGYCKPSPSPQEFEHAGYLSSPTQEALCLPQQLQQQQQQQQQQQSSLNPASNNNSNNNADNNGNLVVSQQ
4) SNTSLSSLSSLSSSNNTSSNHSSSNTLAAAAAATTSLPSATTLPPATTP
256
120
344
457
337
241
425
505










Molecular Recognition Features






MoRF SequenceStartStop




NANANA