<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25192

Description Uncharacterized protein (Fragment)
SequenceNTQRIRCVLCCCTCCTQWISQIKSFEKRNCTNICKRAGHEMYADKRGLEKPGSTLSAAAAAALQQQQQQQHHHVLQLQHQQQQQHLQHQQHHMQQHMHTHHNFQQHEPTTLSQQQHLQQQQQQQQQQQQQQQQQQQQQASQQQQQQAAGMFTRFDANKSTKGASKMRRDLINAEIANLRDLLPLPQSTRQRLSQLQLMALVCVYVRKANYFQQVFKRHNALHQHHQTATPNIGFSKALSGFLMMLTQNGKLLYISDNAAEYLGHSMEDLLIHGDSVYDIIDKQDHATIQAELNRNVPPQPGGSSSSSNVGVGAGVGVGVGDSTASNGTGGASSLEGEHRMFLCRMNVSRNARRQMRFGDQKVVLVQGHYLSFLPLCSRNEPVFLATCTPIAMPETRECVVQGATNVFTTIHSMDMKIAHIDKNGEFHLGYDKASLQGTSWYNLIHSENLREAQSKHRLITQSEQDRSCILLVRMQRSSGEYTWVHVVLQVRDSPDSTQQPVIVCTNQVLNDREASIMLANSWLYHYYTVQSKIQFGMPLDSAMRVPPGSSSTGYYSSHQQPHGGGATSVGLGISGATAGMSSVFGSHHAHHHHHHTTAATSYHHHHPHMGAAYGGVYHAEGTLELKEDQQLYGYQSGTGPEPVDYSQVNGTPTGSSQKPTQSATPPPPKKRARNKLEPLYLHAERSPAAAITPEPDCYALHPGAAYATAAAGVAASSSDATASVIYATIVPTRPRLLNKTLPPDPADFIEQWNPSPPWSESAQKASLDSFGSSHELSPCITTTPPTPTSATPHHGGISAQTIGPAFSFEWMSDPLVPVAYQQWSPATGDHHQHLSQHLAAAQQQHQQHQHQQQQQPHPQHTQLTLHGVHAERVELAAETMVGTGRADATEPVEDRDPKN
Length899
PositionTail
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.06
Grand average of hydropathy-0.661
Instability index57.00
Isoelectric point7.32
Molecular weight99499.72
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:EnsemblMetazoa
protein-containing complex	GO:0032991	IEA:EnsemblMetazoa

GO - Biological Function
DNA-binding transcription factor activity	GO:0003700	IEA:EnsemblMetazoa
protein heterodimerization activity	GO:0046982	IEA:EnsemblMetazoa
sequence-specific DNA binding	GO:0043565	IEA:EnsemblMetazoa

GO - Biological Process
branch fusion, open tracheal system	GO:0035147	IEA:EnsemblMetazoa
epithelial cell migration, open tracheal system	GO:0007427	IEA:EnsemblMetazoa
imaginal disc-derived leg joint morphogenesis	GO:0016348	IEA:EnsemblMetazoa
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25192
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     109.34|      15|      15|     113|     127|       1
---------------------------------------------------------------------------
  114-  129 (29.79/ 9.10)	QQHLQQQ...QQQQQQQqQ
  130-  144 (29.60/ 9.00)	QQQQQQQ...QQASQQQ.Q
  831-  848 (25.27/ 6.61)	HQHLSQHlaaAQQQHQQ.H
  849-  862 (24.68/ 6.29)	QHQQQQQ...PHPQHTQ..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.48|      22|      72|     559|     582|       4
---------------------------------------------------------------------------
  312-  333 (24.57/11.26)	..GAG.V.GVGVGdstASNGTGGASS
  561-  582 (40.71/27.99)	PHGGGAT.SVGLG...ISGATAGMSS
  702-  723 (25.20/ 8.52)	PGAAYATaAAGVA...ASSSDATAS.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.98|      19|     246|     287|     306|       8
---------------------------------------------------------------------------
  287-  306 (32.07/21.34)	TIQAELNRNVP.......PqPGGSS....SS
  528-  557 (24.91/11.23)	TVQSKIQFGMPldsamrvP.PGSSStgyySS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.52|      14|      16|     627|     642|      10
---------------------------------------------------------------------------
  629-  642 (27.14/15.15)	QQLYGYQSGTGPEP
  646-  659 (23.38/ 6.55)	SQVNGTPTGSSQKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.13|      13|     184|     584|     600|      12
---------------------------------------------------------------------------
  215-  227 (26.57/ 6.93)	FKRHNALHQHHQT
  584-  596 (29.55/17.56)	FGSHHAHHHHHHT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25192 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AYQQWSPATGDHHQHLSQHLAAAQQQHQQHQHQQQQQPHPQHTQLTLHGVHAERVELAAETMVGTGRADATEPVEDRDPKN
2) EDQQLYGYQSGTGPEPVDYSQVNGTPTGSSQKPTQSATPPPPKKRARNKLEPLYLHAERSP
3) MYADKRGLEKPGSTLSAAAAAALQQQQQQQHHHVLQLQHQQQQQHLQHQQHHMQQHMHTHHNFQQHEPTTLSQQQHLQQQQQQQQQQQQQQQQQQQQQASQQQQQQAAGMFTRFDANKSTKGASKMRRDL
4) RLLNKTLPPDPADFIEQWNPSPPWSESAQKASLDSFGSSHELSPCITTTPPTPTSATPHHGGISAQTIG
819
627
41
735
899
687
170
803










Molecular Recognition Features






MoRF SequenceStartStop




1) LEPLY
676
680