<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25176

Description Uncharacterized protein
SequenceMKENNKILQLINVAWRERWTDSQWGINIKKVLPRGVSGDVYNLADCLLQQAVIGSTANSLVLNYLKHSLCAHLVSHAAVLRCIAKYDKLGRVYCVTALLEFLVSIIDGITCRIKSEESLLPGAVVQLVLWIMQIFARTLQQYEMRGEMSAEQSYMLDQSCLLIEHLTQQQFVLAMLNVGCHEELEALDRLRDLYASIKASLTNSNFTLSAATAEQQLKQLAYIDAKHLELQTLNPCPTVEKISCCVQPLLAVEVLLNPCKDTSYYVAELQMLQRLKGYTNTRLFYEIIRAGFLTLSNVADTSPDTMWGAFMFFKMPHIIKQLHALQRVPGEQPLAATDYIPELVEALELLIEDNLLLDFMDTKCSCNIIEFLLNDWTKQQLVNDVHVKKFASQREAASMLLKKCDNGQQTPSNINFIKRAEVPLSGVLKTLCTNKLPDMVNVLCQVPVGNSFELILSVATVEGRLKTFVSRLIQCNENSKQLPGELGKLSVIRSTLFDVSFLMLTSIVQTYGSDVVLSERGDSFFEKWVRECMMERNKLKNPRQILALCDDSIVDELLLSLSKPEAAQLKPSNLTWQDICLNLPGVLHHVLIAWEQETLSSADVKSILDNMKRRLFSFTVCATSFLCAYMYSVRETELLKPLNMIQQFLAPLTTEELSSQENSKERLALSYQIIRKMQHDVHPAPNTKSRLISHTPLIEQFRECWRCVAEAGHLPVRAAQTLESLLLAGGASWLVTQLVEQLLSCKYMRDMAKCMDIVFAVMHLDIERSTEALLQYVVAPLILRRQGEDINEPQSLVLARLCVYCIISCLETRSSANAAAAALKKRSRSHDDDELQGVANAAKVRKVIGDGSNENSNDFADASGTNVAAMLSTPSAELRATPLNLKEPLQSSVKHIFRVFLQFVSGDELSPKAVFVYQFISLLVECGGERVTPVLRLLPANLMQQLLKVLATDDIRVGLISRLYDLRLQGGRQAAVADLCLWRNMQLARHSIHL
Length994
PositionTail
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.07
Grand average of hydropathy0.062
Instability index45.97
Isoelectric point6.41
Molecular weight111699.79
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblMetazoa

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:EnsemblMetazoa

GO - Biological Process
ecdysone-mediated induction of salivary gland cell autophagic cell death	GO:0035072	IEA:EnsemblMetazoa
pupal development	GO:0035209	IEA:EnsemblMetazoa
regulation of transcription by RNA polymerase II	GO:0006357	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25176
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.63|      22|     244|     184|     218|       1
---------------------------------------------------------------------------
  184-  205 (38.22/44.82)	LEALDRL......RDLYASIKAS.LTNSN
  269-  297 (28.41/ 8.83)	LQMLQRLkgytntRLFYEIIRAGfLTLSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     217.66|      62|     244|     519|     586|       2
---------------------------------------------------------------------------
  434-  485 (49.33/29.71)	..................NKL...PDMVNV..LCQVPVGNsfELILSVATVE.GRLKTfvSRLIQ...CnensKQLPGE
  522-  586 (100.96/87.14)	DSFFEKWVRECMME...RNKLKN.PRQILA..LCDDSIVD..ELLLSLSKPEaAQLKP..SNLTWQdiC....LNLPGV
  588-  647 (67.37/40.15)	HHVLIAWEQETLSSadvKSILDNmKRRLFSftVCATSFLC..AYMYSVRETE..LLKP..LNMIQQ.............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.22|      11|      27|     315|     325|       8
---------------------------------------------------------------------------
  315-  325 (19.62/12.11)	MPHIIKQLHAL
  340-  350 (16.60/ 9.11)	IPELVEALELL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25176 with Med24 domain of Kingdom Metazoa
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