<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25175

Description Uncharacterized protein
SequenceMLSLLQEKRPLKRTRLGPPDIYPQDAKQREDELTPTNVKHGFTTTPPLSDEFGTAHTSNVNASKVSAFFSGVLAKKEELMTLQDTVRKKQQINCKDNFWPVSPRRKCTVDAWFKDLAGNKPLLSLAKRAPSFNKKEEIFITLCENQVNMQRATWFIKLSAAYTLSFTESKNKKRSIYDPAAEWTGNMIKFMKELLPKLQEYYQQSHDKNGMQANGSSSSSTASSTSSNSNGSANSSNNNNNTSNNTNTVGNATPNVIPVPSMSSPLPPIHSPANGQPGAVGSAAAGGAVTGAAATPGTALATLGGSAAVGAAGANAGAVPPGSSISGIGSQFEDSRNALKYWKYCHQLSKYMYEESLLDRQEFLNWILDLLDKMRTQTSFDEPLKKLVLSFALQYMHDFVQSERLCRKMANLVAKKLAQLLNAAVEQQQQQQQQQALIKSQAMELDAPEEQQQHPTIDPYEQALHDYMNCPHHRDIVLYLSTILQVITIECPTALVWSGIAAHRAPSSLVGSPLDHLPLAPSVLPMPSRCPRTNHELRKQLRAAEADIVLRTQHAEQRWFASKWLSAGKNHYTNVLATLDHLDTHCFERMDQCNSIDTLYTHIFPPQPAQLRRPDDDSQQQQQQQQRAPYEPKQDADTVRILCEWAVSSQRWGEHRAIVVAILLDKRQIDVTSTPADLCGDKEDKDSLASGAGIIDGLPVFQHVLMHFLDHDAPVLDEHNSSAQQRTEFTNLVQLFSALIRHDVFSHNAYMHTLISRGDLLLESMLVHKTTAKSSPPPPAPPPPNSSATTHGFDDDGFGSGIGIDFKHNEFDDSNVDDDLDKLVQNIKEKGQQHEAPDSPKIGAPGDGDGGVDTPASGGSISRHYVYTKHFPIPQDDPSMSSYSSESNQRYILLFGVGKERDEKKHAVKKMSKEIGKLFTKKFSIDVAEGGKVKKHSRNEFNFEATTAKCQHMAYFDQHVVTAQCAANVLEQLNGFAQGSNNYLPVQEHVAFLFDLMELALNIYSLLELCDHLLKELPEVEHQLQLKKSNMVRGYTTSLALYIVSILRRYHSCLLLSPEQTVSVFEGLCRTIRHVSDPSECSSAERCILAYLSDLHESCILLQGKEQAAEYYQQLNCIKRFKDIFNTPEQLSITPQAYNPQLLQELFVAPRRGGKLESHWLRQLHESPANVYSFVSNAVIAVCRETDNERLNDVALACAELTASCNVLSEEWIAALQSLCSGSKSPRYPHLGGQVDIGQGKTHNALAVFVCILVARHCFSLADFVSKFALPTLARSVSGGGELSVDAEAGARLTCHLVLKLFKTLEIPQPGMYSVSTSPNPLHAVGSDFSIRLSCDRHLLVGAHKTIPIAAVLAVLKAILIVVDNAALKTPLAASGLGSSSSCSAFGSGKRSGFNTPVHPGSTPKSNEQRPADLSQILGTSDLQLGSLGSEQESLQQPTGSSLGGNEQISLLEFAQAVLKQICAQEHVLERCLKNAEQLCDMIIDEMLTAKQAQRVLHMICYPEAEFNIISELDQRSMIVRILENLDQWTLRISWLDLQLMYRQSLSNNTSLSNNTELNVWLDTVARAAIDVFHMEEVTLPGALKTTHKPKPSTWLVAPLIAKLTPAVQGRILRVAGQVLESMNYFSKVSKSDCNSSGSGDEREKSNSCHSSNSYGGGGSIMARNKKMPLNYQPFLGLILTCLKGQDEYKENLLVSLYSQLSQCLQSFAELDTIGGIDEPQAREEILDALQLRFSLVGGMFDAIQKNSTPTTDWAILLAQLVCQGVVDLSCNRELFTTVVDMLATLVHSTLVSDSQSERDENKKLYLNLMKKLKKEIGEKNNASIRVIRQLLPLYKQPTEVIACEHAGMDTKGNKICDMDKKQLRISDKQRISVWDILEGHKNPAPLSWVWFGAVKLERKPLTYEEAHRNLKYHTHSLVKPSSYYYEPLPLPPEDIEPVPEKICIKDEMMKADTPSSVDQSPSAVVGTGRGRGKGTTTRKRKPKNPKTPPVVNTQQQQPQLAPQPQQPPNVQQQQQQQQMQQQQHMQQQMQPNQMGQMPMNMQMNMQQFGPNAMMQQQTALMQQQQQQQQQQQQMQQMAPNQMQQQLNVGGNGQPNAQMNFMQGPGPGGPQGMPGQQQQQQQWHNTPQQQQQQPQQYHNQYQHQQNMQMNRIERPPLNSNSKQALSQMLRQRQPGSFQQQQQQPPGGFNPMQQQAQQQQGPQQQQINAQQLRQQQQQQQQMNAQQNPQAAAAFNAMQQQQQQPNVQQQQQMNPNQQQLQQQQQQQQQQQQFMRGNMRAMAPSQMGGMNMVGQGMPQNPMLQQQQMAQGMVGMVNPNANPMMQGGGAGGNGGVGVGVGVGVGAGGNNPNMGMGGMPQQGLIQQQQQVQFQNFQNQYQQQQQQQGMQQQGGGGGGGVGVGMAPNQQQQQQAGLMNNFNPQMQQAQRNNPDFMAAAVVAQQQQQQQQQQQQQQQQRGVPGGMMAGNRGQYMNQAPNVTMTNMMGPGPGGVGVGVGQVPPYARQQTTGGGKPGVLPAQQQFQQQQLRHQQMMQMQGMAGGGMGGGPQAGGGAGAGGGGGMVQQQQSMNQQQTPNLVAQLQRQMTNQPNMMGQQQQYPHQPPPY
Length2599
PositionKinase
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.06
Grand average of hydropathy-0.584
Instability index55.08
Isoelectric point7.26
Molecular weight287432.67
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IEA:EnsemblMetazoa
mediator complex	GO:0016592	IEA:EnsemblMetazoa
polytene chromosome	GO:0005700	IEA:EnsemblMetazoa

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:EnsemblMetazoa

GO - Biological Process
chaeta development	GO:0022416	IEA:EnsemblMetazoa
compound eye development	GO:0048749	IEA:EnsemblMetazoa
ecdysone-mediated induction of salivary gland cell autophagic cell death	GO:0035072	IEA:EnsemblMetazoa
imaginal disc-derived leg segmentation	GO:0036011	IEA:EnsemblMetazoa
positive regulation of canonical Wnt signaling pathway	GO:0090263	IEA:EnsemblMetazoa
regulation of transcription by RNA polymerase II	GO:0006357	IEA:EnsemblMetazoa
sex comb development	GO:0045498	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25175
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            11|     667.41|      44|      50|    2194|    2237|       1
---------------------------------------------------------------------------
 2013- 2054 (68.42/17.05)	QQ...QQQQ....Q......MQ..Q....................QQHMQ..Q.....QMQP..NQ.MGQM..P...MNMQM...N.MQQ...FgpNAM.
 2058- 2103 (65.48/16.02)	QTalmQQQQ....Q......QQ..Q....................QQ.....Q.....QMQQmaPN.QMQQ..Q...LNVGG...N.GQPNAQM..NFMQ
 2116- 2161 (56.97/13.03)	QQ...QQQQqwhnT......PQ..Q....................QQQQP..Q.....QYHN..QY.QHQQnmQ...MNRIE...R.P....PL..NSNS
 2163- 2192 (50.34/10.71)	QA...LSQM....L......RQ..R....................QPGSF..Q........Q..QQ..............QQ...P.P...GGF..NPMQ
 2194- 2237 (89.84/24.57)	QA...QQQQ....G......PQ..Q....................QQINA..Q.....QLRQ..QQ.QQQQ..Q...MNAQQ...N.PQAAAAF..NAMQ
 2239- 2280 (68.84/17.20)	QQ...QQPN....V......QQ..Q....................QQMNPnqQ.....QLQQ..QQ.QQQQ..Q.....QQQ...F.MRGN..M..RAMA
 2282- 2321 (56.62/12.91)	S.....QMG....G......MNmvG....................QGMPQ..N.....PMLQ..QQ.QMAQ..G...MVGMV...N.PNA......NPMM
 2322- 2376 (41.01/ 7.43)	QG...GGAG....G......NG..GvgvgvgvgvgaggnnpnmgmGGMPQ..Q.....GLIQ..QQ.QQVQ..F.......Q...N.FQ.......NQYQ
 2377- 2420 (60.28/14.20)	QQ...QQQQ....G......MQ..Q....................QGGGG..GggvgvGMAP..NQ.QQQQ..QaglMN.NF...N.PQ.........MQ
 2421- 2466 (55.53/12.53)	QA...QRNN...........PDfmA....................AAVVA..Q.....QQQQ..QQ.QQQQ..Q...QQQQR...GvPGGMMAG..NRGQ
 2499- 2552 (54.08/12.02)	RQ...QTTG....GgkpgvlPA..Q....................QQFQQ..Q.....QLRH..QQmMQMQ..G...MAGGGmggG.PQAGGGA..GAGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.55|      14|      26|    2556|    2569|       6
---------------------------------------------------------------------------
 2556- 2569 (26.66/10.85)	MVQQQQSMNQQQTP
 2585- 2598 (29.89/13.29)	MMGQQQQYPHQPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.25|      22|      25|    1962|    1985|       7
---------------------------------------------------------------------------
 1962- 1985 (29.17/19.66)	PsAVVGTGRGRGKgTTTRKRKPKN
 1989- 2010 (42.09/19.84)	P.PVVNTQQQQPQ.LAPQPQQPPN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25175 with Med12 domain of Kingdom Metazoa
Unable to open file!