<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25169

Description "Uncharacterized protein, isoform B"
SequenceMNQNQIQQLTSHLSQALDQNYDVVNMEAVLSVICALEGTTITKEQLEATRLAKYINQLRRRTKNDQLARRAKSLLKKWREMVGINQQTSIDSQSKHMDQSTFKPMVETNLTGSESNATEADLNQIQYNSQPFSPTLQRVISNLHTNIDSSEPKLHHQTNFSSLINNNINIDNRDNRDESLTIVNKQIQYKPQNSSTITNEHSSNSVSSAFVANDNFNQASIVIDIVSDSDENDTVNSQKKLETESSLLATPSHYFRPKKLKKDKKYKDRDSRDKPLFNLKGETSQQSKNSKKSKTPKVYSTDPEILSLSNSSMSSLLSGDAVSGNFQTRLHPPAADLTFAGRFKSVGRLETFSNVITVQANGQKSTTSVIDTSIEVPTRPIYEDNNDSNTSCSRLSPYDELEPKLDQNRLKSCEETIPKKRGRKKGSKGVDSLIAKESSLSQQIFFGSGVKKVKTTKELFNEIQSRKLSTSFNRGENTTAPSVTNRILSTSSTNVRNLECRSLHTRPASSCSETSIHSPHALEPFSSNVSLAGTEKHSNTLEDPGNTDSDTVTSELSRDSKPRNKRIHSLDSNSNSHQQTSSAKSAEDVVMKTDYNDVRTQLMHIVRSLNSPLTVDETEKRYQAEIVPCTCIIFEDMPKESFEHNKLSQIGKESDLVNKGSSDIDISRDKRHNEQTAIKTENCVVDAAEQTIAQKPMKSIFDLDFDDDDDPLHTIIKHVSPTESNVKTKLDIDFDSTDSNVVSLAEEDINKDSKAEITDSFPADQESSNIIAEPISIYTVREDPKCIAKQRFDIQTNDVTNFHINALHNYYIPNINGNWNSIDSSLVLKSSSITEFLQTLESYTVTDGSDVVPKYGSLTYEQRIRKDLSYLKFVQNYKSKSFKSFMPPFLGVAKCLPTCRLAAKRLKDKTKSLPTINSANMLVKQEKSEMHCSYFANNSSGPNPLRVEVTINDTQKNNESQVRYSDDNPIKHNAELSYNLLKVVNSENHENFKKSDDSNAGYTNMKYRRYRRNSTCSSSNLQLTQDSINEKLRNQRAEYTEISEQSESNIERNRKKRRKRNNSTPYDKHNIKNLTIEEKPRIKRIKIAINGNVSTHRQISVISSGDISCGDEEEAHIEMSDMEVGFDNIGYSHYAPGASDDDHESNRSHSTTVDSILADDDHMENDDDNNSDDEEYAIVQRPLAHGGGSNNHIVLTIKKTPSKINSPANSISAISPIVGVATEVEMSTGKQQDAEIVTSNLSVESKCEAHGSESILCQTLLQ
Length1262
PositionUnknown
OrganismDrosophila mojavensis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.822
Instability index49.22
Isoelectric point6.07
Molecular weight141451.84
Publications
PubMed=17994087
PubMed=18057021

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25169
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.90|      25|      26|    1008|    1033|       1
---------------------------------------------------------------------------
 1008- 1033 (39.94/27.74)	RRYRRNSTCSSSNlQLTQDSINEKLR
 1057- 1081 (42.96/25.72)	RRKRNNSTPYDKH.NIKNLTIEEKPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.71|      25|      27|     943|     967|       2
---------------------------------------------------------------------------
  915-  946 (21.63/10.32)	...TIN...SAnmlvkQEKSEMHCSYfannsSGPNPLR
  947-  971 (42.83/30.04)	VEVTIN...DT.....QKNNESQVRY.....SDDNPIK
  974-  997 (21.25/ 9.97)	AELSYNllkVV.....NSENHENFKK.....SDD....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.09|      14|      18|     510|     524|       4
---------------------------------------------------------------------------
  510-  523 (26.17/10.59)	SCSETSIHSPHALE
  574-  587 (19.91/ 6.14)	SNSHQQTSSAKSAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.94|      17|      18|     466|     482|       6
---------------------------------------------------------------------------
  466-  482 (29.71/19.73)	RKLSTSFNRGENTTAPS
  486-  502 (29.24/19.28)	RILSTSSTNVRNLECRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     170.32|      54|      56|      87|     142|       7
---------------------------------------------------------------------------
   87-  142 (86.37/51.21)	QTSIDS.QSKHMDQSTFKPMVETNLTGSESNATEADLNQIqyNSQ.PFSPTLQRVISN
  144-  199 (83.96/44.10)	HTNIDSsEPKLHHQTNFSSLINNNINIDNRDNRDESLTIV..NKQiQYKPQNSSTITN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     188.87|      63|     158|     230|     297|       8
---------------------------------------------------------------------------
  230-  297 (98.22/75.46)	DENDTVNSQKKL....ETESSL....LATPSHYFrPKKLKKDKKYKDRDSrdkpLFNLKGETSQQ...SKNSKKSKTPK
  384-  457 (90.65/55.93)	DNNDSNTSCSRLspydELEPKLdqnrLKSCEETI.PKKRGRKKGSKGVDS....LIAKESSLSQQiffGSGVKKVKTTK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.09|      30|      49|     619|     650|      10
---------------------------------------------------------------------------
  619-  650 (48.21/39.17)	EKRY..QAEIVPCTCIIfeDMPKESFEHNKLSQI
  669-  700 (44.88/29.27)	DKRHneQTAIKTENCVV..DAAEQTIAQKPMKSI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25169 with Med26 domain of Kingdom Metazoa
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