<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25164

Description Uncharacterized protein
SequenceMLSLLQEKRPLKRTRLGPPDIYPQDAKQREDELTPTHVKHGFTTAPQLTDEFGTAHTSNVNASKVSAFFSGVLAKKEELMTLQDTVRKKQQINCKDNFWPVSPRRKCTVDAWFKDLAGNKPLLSLAKRAPSFNKKEEIFITLCENQVNMQRATWFIKLSAAYTLSFTESKNKKRSIYDPAAEWTSNMIKFMKELLPKLQEYYQQSHDKNGIQANGSSNSPTTSSVSSNSNGTANSSSSSNNNSSSNSSSVSSATSNVIPVPSMSSPLPPIHSPANGQTSAAGNAAAGGAVPGQSAPPGTALATLGSSATGGAAGANAGAVPPGSSISGIGSQFEDSRNALKYWKYCHQLSKYMYEESLLDRQEFLNWILDLLDKMRTQASFDEHLKKLVLSFALQYMHDFVQSERLCRKMANLVAKKLAQLLNAAVEQQQQQQAVIKSQAMEIDGADEQLQQQQPNIDPYEQALHDYMNCPHHRDIILYLSTILQVITIECPTALVWSGIAAHRAPSSLVGSPLDHLPLAPSVLPMPSRCPRTNHELRRQLRAAEAEIVLRTQHAEQRWFASKWLSAGKNHYTTVLATLDHLDTHCFERMDQCNSIDTLYANIFPPQSTQLRRPEEDPQQQQQPRPPYEPKQDADTVRILCEWAVSSQRWGEHRAIVVAILLDKRQIDVTSTPADQCGDKEDKDSLASGAGIIDGLPVFQHVLMHFLDHDAPVLDEHNSSPQQRTEFTNLVQLFSALIRHDVFSHNAYMHTLISRGDLLLESMLVHKTTAKSSPPPPAPPPPNSSATTHGFDDDGFGSSIGIDFKHNEFDDSNVDDDLDKLVQNIKEKGQQHEAPDSPKIGPPGDGEGGVDTPATGVSISRHYVYTKHFPIPQDDPSMSSYSSESNQRYILLYGVGKERDEKKHAVKKMSKEIGKLFTKKFSIDVAEGGKVKKHSRNEFNFEATTAKCQQMAYFDQHVVTAQCAANVLEQLNGFALGNNNYLPVQEHVAFLFDLMELALNIYSLLELCDNLLKELPEVEHQLQQKKSNMVRSYTTSLALYIVSILRRYHSCLLLSPEQTVSVFEGLCRTIRHVSNPSECSSAERCILAYLSDLHESCILLQGKEQAAEYYQQLNCIKRFKDIFNTPEQLSMAPQGYNPQLLQELFVAPRRGGKLESHWLRQLHESPANVYSFVSNAVIAVCRETDNERLNDVALACAELTASCNVLSEEWIAALQSLCSGSKSPRYPHLGAQVDIGQSKTHNALAVFVCILVARHCFSLADFVSKFALPTLARSVSGASGGELSVDAEAGARLTCHLVLKLFKTLEIPQPGMYSVSTSPNPLHAVGNDFSIRLSCDRHLLVGAHKTIPIAAVLAVLKAILIVVDNAALKTPLGASGLGSSGSGSAFGSGKRSGFNTPVHPGSTPKSNEQRPADLSQILGTSDLQLGSLGSEQESLQQPTGSSLAGNEQISLLEFAQAVLKQICAQEHVLERCLKNAEQLCDMIIDEMLTAKQAQRVLHMICYPEAEFNIISELDQRLMIVRILENLDQWTLRISWLDLQLMYRQSMSNNTSVSNNTELNVWLDTVARAAIDVFHMEEVTLPGAQKPIHKPKPSTWLVAPLIAKLTPAVQGRILRVAGQVLESMNYFSKVSKSDCNSSGSGDEREKSNSCHSSNSYGAGGSMAARNKKMPLNYQPFLGLILTCLKGQDEYKENLLVSLYSQLSQCLQSFSELDTIGGIDEPQAREEILDALQLRFSLVGGMFDAIQKNSTPTMDWAILLAQLVCQGVVDLSCNRELFTTVVDMLATLVHSTLVSDSQSERDENKKLYLNLMKKLKKEIGEKNNASIRVIRQLLPLYKQPTEVIACEHAGMDTKGNKICDMDKKQLRISDKQRISVWDILEGHKNPAPLSWVWFGAVKLERKPLTYEEAHRNLKYHTHSLVKPSSYYYEPLPLPPEDIEPVPEKICIKDEMMKADTPSSVDQSPSAVVGGTGRGRGKGTTTRKRKPKVSKTPPVVNTQQQQPQLAPQPQQPPNVQQQQQQQQMQQQQHMQQQMQPNQMGQMPMNMQMNMQQFGPNAMMQQQNALMQQQQQQQQQMQQMGPNQMQQQLNVGANGQPNTQMNFMQGPGPGGPQGMSNQQQQQQQWHNAPQQPQQQPQQYHNQYQHQQNMPMNRIERPPLNTNSKQALSQMLRQRQPSSFQQQQQQPPGGFNPMQQQAQQQQQQGPQQQQMNAQQLRQQQQQQQMNAQQNPQAAAAFNAMQQQQPNVQQQQQMNPNQQQLQQQQQQQQQQQFMRGNMRAMAPNQMGGMNMVGQGMPQNPMMQQQQMAQGMVGMVNPNANPMMQGGGAGGNGGVGVGVGVGVGAGGNNPNMGMGGMPQQGMIQQQQQQVQFQNFQNQYQQQQQQQGMQQQSGGGGGVGVGMTPNQQQQQAGLMNNFNPQMQQAQRNNPDFMAAAVVAQQQQQQQQQQQRGVPGGMMAGNRGQYMNQAPNVTMTNMMGPGPGGVGVGVGQVPPYGRQQPTGGGKPGVLPAQQQFQQQQLRHQQMMQMQGMAGGGMGGGPQGAGGAGAGGGGGMVQQQQSMNQQQTPNLVAQLQRQMTNQPNMMGQQQQYPHQPPPY
Length2589
PositionKinase
OrganismDrosophila mojavensis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.06
Grand average of hydropathy-0.580
Instability index56.43
Isoelectric point7.34
Molecular weight286461.77
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IEA:EnsemblMetazoa
mediator complex	GO:0016592	IEA:EnsemblMetazoa
polytene chromosome	GO:0005700	IEA:EnsemblMetazoa

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:EnsemblMetazoa

GO - Biological Process
chaeta development	GO:0022416	IEA:EnsemblMetazoa
compound eye development	GO:0048749	IEA:EnsemblMetazoa
ecdysone-mediated induction of salivary gland cell autophagic cell death	GO:0035072	IEA:EnsemblMetazoa
imaginal disc-derived leg segmentation	GO:0036011	IEA:EnsemblMetazoa
positive regulation of canonical Wnt signaling pathway	GO:0090263	IEA:EnsemblMetazoa
regulation of transcription by RNA polymerase II	GO:0006357	IEA:EnsemblMetazoa
sex comb development	GO:0045498	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25164
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     531.45|      49|      49|    2004|    2052|       1
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 2004- 2043 (85.82/25.26)	..................................PQP.QQP.....P...NV...QQQQQ....Q..........QQMQQ..QQHMQ.QQ..........MQPNQ...MGQ....M.PMNM
 2044- 2095 (77.41/22.08)	QM.NMQQFGP.....................namMQQ.QNA.....L...MQ...QQQQQ....Q..........QQMQQmgPNQMQ.QQ..........LNVGA...NGQ......P.NT
 2124- 2157 (52.14/12.53)	...................................AP.QQ......P.........QQQP....Q..........QYHNQ..YQH.Q.QN..........MPMNR...IER....P.PLNT
 2165- 2218 (70.26/19.38)	QM..LRQRQP....................ssfqQQQ.QQP.....PggfNP...MQQQA....Q..........QQ.QQ..QGPQQ.QQ..........MNAQQ...LRQ....Q.QQQQ
 2219- 2285 (70.26/19.38)	QM.NAQQ.NP.................qaaaafnAMQ.QQQ.....P...NV...QQQQQmnpnQ..........QQLQQ..QQQQQ.QQqqfmrgnmraMAPNQ...MGG....M.NM..
 2316- 2412 (55.45/13.78)	MM.QGGGAGGnggvgvgvgvgvgaggnnpnmgmgGMP.QQ......G...MI...QQQQQ....QvqfqnfqnqyQQQQQ..QQGMQ.QQsgggggvgvgMTPNQ...QQQqaglMnNFNP
 2413- 2464 (68.79/18.83)	QM.QQAQRNN........................PDF.MAA.....A...VV...AQQQQ....Q..........QQQQQ..QRGVP.GG.........mMAGNRgqyMNQ....A.P.NV
 2465- 2532 (51.33/12.23)	TMtNMMGPGP.............ggvgvgvgqvpPYGrQQPtgggkP...GVlpaQQQFQ....Q..........QQLRH..QQMMQmQG..........MAGGG...MGG....G.P...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.03|      14|      32|    2546|    2559|       3
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 2546- 2559 (27.33/ 9.07)	MVQQQQSMNQQQTP
 2575- 2588 (29.70/10.56)	MMGQQQQYPHQPPP
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.46|      26|      46|    1810|    1838|       6
---------------------------------------------------------------------------
 1810- 1838 (38.53/37.18)	MKKLKKEIGEKNNASirvIRQLLPLYKQP
 1859- 1884 (45.93/34.52)	MDKKQLRISDKQRIS...VWDILEGHKNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.93|      16|      35|    1451|    1466|      10
---------------------------------------------------------------------------
 1451- 1466 (27.87/20.06)	LLEFAQA..VLKQICAQE
 1487- 1504 (26.06/18.19)	MLTAKQAqrVLHMICYPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.60|      34|      39|    1274|    1307|      13
---------------------------------------------------------------------------
 1274- 1307 (56.36/38.75)	SVSGASGGELSVDAEAGARLTC..HLVLKLFKTLEI
 1314- 1349 (56.25/38.66)	SVSTSPNPLHAVGNDFSIRLSCdrHLLVGAHKTIPI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25164 with Med12 domain of Kingdom Metazoa
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