<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25141

Description Uncharacterized protein
SequenceMEVDQLTLADVVFVIENSAINGAYLNELKTNYILPTLEHFTQGSIDEREFLIAERYATLYGIVTYRTASNLLEPVCTTYGPFVQPQKVIETIERLPLVGGGMESHAHMAEGFAAAHGCFDDISEQRHIMEQGNIQRHCILICNSPPYQMSVNESWKYKGKSCEQLAALFNERKINLSIIAPRKMPVLFKLFIKADGDQPITTKNYAKNIRHLVLLKGYSLKERAPSPNSMSVGGSAAAQHQMGAPQAQQTAVQVMNNNPNGQQPGQVLNMPMDTTPAQQQQPGSGPQQQQVMNMNAMQQQQQQQQSQQQPGVMTPQQQQQLLQQQQQQQQQQQQFVPNQMQNANFQPNVVPGQNRWLYPNQPGQRPAFMQTPGNNMPLQQTQNPNSALISRINAPPNQTVNSLQQQQLQQQQQQQQQQRLQMINHQQFNQLQQQLAQQQQQQQQQQQQQQQQQQQQQQQQQQHPQQQVNPNANTNMLPTVSSAPNQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQEQSSLREKIWTGVLEWAEKAKNDQQKIPHSLQCTVCTNIKDGEPEIKADNWPPKLLMQLMPKHLVGNIGGQFLKDSKMVVFRPAPGEALDSLAKMMTSGYAGCVHFSALPNTPACDIKVLILLYTADRNAFLGFIPNNQTMFVERLRKVIQQKQSHGNMQQQQQMPPQQQMQQLMQQQGKSPMELQQQQQQQQQQQQQMQQDNSQQQQPHYNQYAQLNMQMGGAPGGNGGGGMPMQPQMQMNMMQQQQQQQQRMPLGVPVANPNLQQQLQQVPQQQQQRMVRPMLGNNNPGLRQLLQHQTPGNQFRPQMGGQPNQMGAGGPMVGNRNFDDGNYDFM
Length854
PositionUnknown
OrganismDrosophila mojavensis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.985
Instability index73.31
Isoelectric point8.79
Molecular weight97291.32
Publications
PubMed=17994087

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP25141
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     321.60|      43|      44|     429|     471|       1
---------------------------------------------------------------------------
  298-  345 (64.68/ 9.23)	QQQ..QQQQQSQQQpgvmtPQQQQQLLQQQQQQQQQ..QQQFVPNqmqnANF
  346-  388 (54.54/ 6.24)	QPNVVPGQNRWLYP.....NQPGQRPAFMQTPGNNMPLQQTQNPN....SAL
  389-  431 (56.40/ 6.79)	ISRINAPPNQTVNS.....LQQQQLQQQQQQQQQQR..LQMINHQ..qfNQL
  432-  477 (83.72/14.85)	QQQLAQQQQQQQQQ.....QQQQQQQQQQQQQQQQQHPQQQVNPN.antNML
  690-  735 (62.27/ 8.52)	.QQLMQQQGKSPME.....LQQQQQQQQQQQQQMQQDNSQQQQPHynqyAQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.83|      15|      15|     486|     500|       2
---------------------------------------------------------------------------
  486-  500 (33.91/ 6.53)	QQQQQQQQQQQQQQQ
  502-  516 (33.91/ 6.53)	QQQQQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.56|      22|      23|     750|     772|       3
---------------------------------------------------------------------------
  754-  778 (37.81/11.14)	QPQMQMNMMQQQQ.QQQQRM.plGvPV
  815-  840 (32.75/ 6.03)	QHQTPGNQFRPQMgGQPNQMgagG.PM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.80|      13|      38|     237|     249|       5
---------------------------------------------------------------------------
  237-  249 (25.58/ 8.74)	AAQHQMGA.PQAQQ
  277-  290 (23.23/ 6.89)	AQQQQPGSgPQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.55|      21|      23|     527|     549|       6
---------------------------------------------------------------------------
  517-  545 (25.15/21.42)	PQeqsSL....rekIWTGvlEWAEKAKNDQQKI
  546-  573 (34.40/22.66)	PH...SLqctvctnIKDG..EPEIKADNWPPKL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP25141 with Med25 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) QQQQQQQQQQQHPQQQVNPNANTNMLPTVSSAPNQQQQQQQQQ
2) RAPSPNSMSVGGSAAAQHQMGAPQAQQTAVQVMNNNPNGQQPGQVLNMPMDTTPAQQQQPGSGPQQQQVMNMNAMQQQQQQQQSQQQPGVMTPQQQQQLLQQQQQQQQQQQQFVPNQMQNANFQPNVVPGQNRWLYPNQPGQRPAFMQTPGNNMPLQQTQNPNSALISRINAPPNQTVNSLQQQ
3) RLRKVIQQKQSHGNMQQQQQMPPQQQMQQLMQQQGKSPMELQQQQQQQQQQQQQMQQDNSQQQQPHYNQYAQLNMQMGGAPGGNGGGGMPMQPQMQMNMMQQQQQQQQRMPLGVPVANPNLQQQLQQVPQQQQQRMVRPMLGNNNPGLRQLLQHQTPGNQFRPQMGGQPNQMGAGGPMVGNRNFDDGNYDFM
452
223
663
494
406
854

Molecular Recognition Features

MoRF SequenceStartStop
1) NRWLY
354
358