<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25140

Description Uncharacterized protein (Fragment)
SequenceMGWQRVRARQTNVICCVLCCSTQWISQIKSFEKRNCTNICERASHDMYADKRGLEKPVTHLATPTHAHALQQQQQQQQQQHHHVLQLQHQQQHLQHQQHHMQQHMQTHHNFQQHEPTPLSQQQQHLQQQQQQQHQQQQQQQQQQQQQQQQQQQQQAAGMFTRFDANKSTKGASKMRRDLINAEIANLRDLLPLPQSTRQRLSQLQLMALVCVYVRKANYFQQVFKRHNALHQHHQTTTPNIGFSKALSGFLMMLTQNGKLLYISDNAAEYLGHSMEDLLIHGDSVYDIIDKQDHATIQAELNRNVPPQPGGSNSSSSGVGVGVGVGVGVGDSTASNGTGGASSLEGEHRMFLCRMNVSRNARRQMRFGDQKVVLVQGHYLSFLPLCSRNEPVFLATCTPIAMPETRECVVQGATNVFTTIHCMDMKIAHIDKNGEFHLGYEKAALQGTSWYNLIHSENLREAQSKHRLITQSEQDRSCILLVRMQRSSGEYTWVHVVLQVRDSPDSTQQPVIVCTNQVLNDREATIMLANSWLYHYYTVQSKIQFGMPLDSAMRVPPGSNSGGYYGAHQQPHGGGAASVGLGMPGSATGMSNVFGSHHAHHHHHHATAAASYHHHHPHMGAAYGGVYHAEGAVELKEDQQLYGFQPGGGASGLEPVDYSQVNGAPTGGSQKSTPSATPPPPKKRARNKLEPLYLHAERSPAAAITPEPDCYALHPGAAYATAAAGVAASSSDASASVIYATIVPTRPRLLNKTLPPDPADFIEQWNPSPPWSESAQKASLDSFGSSHELSPCITTTPPTPTSATPHHGGISAQTIGPAFSFEWMSDPLVPVAYQQWPPATGDHHQHLSQHLAAAQQQH
Length858
PositionTail
OrganismDrosophila mojavensis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.06
Grand average of hydropathy-0.614
Instability index56.02
Isoelectric point7.76
Molecular weight94940.07
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:EnsemblMetazoa
protein-containing complex	GO:0032991	IEA:EnsemblMetazoa

GO - Biological Function
DNA-binding transcription factor activity	GO:0003700	IEA:EnsemblMetazoa
protein heterodimerization activity	GO:0046982	IEA:EnsemblMetazoa
sequence-specific DNA binding	GO:0043565	IEA:EnsemblMetazoa

GO - Biological Process
branch fusion, open tracheal system	GO:0035147	IEA:EnsemblMetazoa
epithelial cell migration, open tracheal system	GO:0007427	IEA:EnsemblMetazoa
imaginal disc-derived leg joint morphogenesis	GO:0016348	IEA:EnsemblMetazoa
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25140
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     120.80|      15|      15|     121|     135|       1
---------------------------------------------------------------------------
   80-   94 (28.56/ 8.75)	QHHHVLQLQHQ.....QQHL
   96-  115 (26.11/ 7.40)	HQQHHMQQHMQthhnfQQHE
  121-  135 (34.86/12.23)	QQQQHLQQQQQ.....QQHQ
  138-  152 (31.26/10.24)	QQQQQQQQQQQ.....QQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     369.25|      84|      98|     545|     631|       2
---------------------------------------------------------------------------
  306-  348 (30.21/ 7.08)	.........PP.qPGGSNSS....S.SGV......GVGVGVGVGvgdsTASNGTGGA.SSL............EGEH..................................
  545-  631 (151.61/77.77)	FGmPLDSAMRV..PPGSNSG....GYYGAHQQPHGGGAASVGLG....MPGSATGMS.NVF............GSHHAHHHHHHATAAASYHHHHP.HMGAAYGGVyhAEG
  642-  725 (111.24/48.86)	YG.........fqPGGGASGlepvDYSQVNGAPTGGSQKSTPSA....TPPPPKKRArNKL............EPLYLHAERSPAAAITPEPDCYAlHPGAAYATA..AAG
  791-  858 (76.18/30.43)	...PCITTTPP..TPTSAT.............PHHGGISAQTIG....PAFSFEWMS.DPLvpvayqqwppatGDHHQHLSQH..LAAAQQQH..................
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25140 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GLEPVDYSQVNGAPTGGSQKSTPSATPPPPKKRARNKLEPLYLHAERS
2) ICERASHDMYADKRGLEKPVTHLATPTHAHALQQQQQQQQQQHHHVLQLQHQQQHLQHQQHHMQQHMQTHHNFQQHEPTPLSQQQQHLQQQQQQQHQQQQQQQQQQQQQQQQQQQQQAAGMFTRFDANKSTKGASKMRRDL
3) RLLNKTLPPDPADFIEQWNPSPPWSESAQKASL
652
39
748
699
179
780










Molecular Recognition Features






MoRF SequenceStartStop




1) RARNKLEPLYLH
684
695