<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25138

Description GH23935
SequenceMNQNQIQQLTSHLSQALDPNYDVINMEAVLAVICTLEGTTITKEQLEATRLAKYINQLRRRTKNDQLARRAKSLLKKWREMVGINQTSSDSQPAITTTATINKPINESIIIVDNVVHPQLSVSASASTSSSSFMPEASNFSLNHLDNSVDFSSFKPKSDIDKSNEPPIVIDIVSDSDENENEARIQSNINRSSFASASSQQQPQQQQAFPAFYPRPKKLKKEKKSRKEREKLATTTATNLLTYLKDDLPLQMPRSIIRNNLAQQQPQQLGRKIYPTDSEILSLSNSSMSSILSGDNTLNNNRSRSNAADLTFAGRFKSLTQFEDNNNPPPVSVNGQKKPEPEQQQQQLYEDYMLHNDSSNSVSRLSPFEEQSIPISHNEGSNKQMPAVNKPQDYQRSENILSQVPKKRGRKKGSKGVDSLIAKESSSLSQQIFFNSGVKKVKTTKELFNDIQSRKLSISYRGDSALPASASVSAAASKLNNRDARPTSSCSETSLHSPHNLETFSTNASQLGNDKFSTILEASVHTDSETLTSAEPSRRHSLEDSNSNNSQQTISATSRLINTECDHDAESRTHSPLSRMNLNHSAGGNYDVSNQLMQLIRSLNAPLSVSETERLYRSQIVPCTCLIFEDAPKLNPTNDENSNNNNNNELNSETVEDHRERGQQQQTESINRNIDNQQKKLTAAADADVTKIMPTSIAPSKPIKSIFDLDFDDDDDPMQSIMQKIPDRNAPNTNEPNELKSTTTNEVNNLHSVVDLQMESDPGNNQTELVPLSIYTVHEDPDCLARQRFEIQTNKVTTFHINALHNYYVPNINGNWNNTGNYGNWNSRINDQTYSVRDGSDVVPKYGSLTYEMIRKDLSELKFKQNLNVKRDGKKMKNYLPTFLGVAKCLPTCRRRAAREWNEMSLKRAASRQQIKSGPSPLRVHIDNANDNNVIADQADGYNLLKVAQEADTKLSYVASELSITNRTSNRCNSSSNNSDCSNFSSQQTQNSINAKVRIRRTSEQVAERHVIERNRKKRRKANRYEQEQQQQLSINEKPRIKRIKIAINGQLPHISNYSSSSCNNSSDEQDEQREEEQDQNEQQEEQNEQQQEEQGEQKRQYRNMQDQNEQQEPEEDNGHETRNKLSNDCQRMLQTVASEDEEDDDDERASLRSRSTTLDEDAVVLEHEYDNDNNDNEYAIIRRGGNNGNNHLVLTIKKTPSKINSPVNSISANISPNIVVAVVKTQNDADNSEGVQKEQQQMTQQATMAATPSCLHNVERCYRYRRRHHRHRYRRPPIDITLKHLFNNNNNNNNSVKQLHRKLFFTNELKFENASGQKERLLNYSSSSSDDSSELETELEAAAAHNYKLKNETDQSVRIAANIHTDYENDEQLCLNTDDDEEEEVDDESEDEAVAAGEEEDEGKAGADAADEGRAASEIIKVSAEIDAANDVTTLAELRLDNNNDMLPTFNSIYAKQIQQQRNNETCEEHNNNFKCGVMQQTTLATTAASNMLEASCEKRLQPALENITGMRAVLLDVDVNVQEDAEAEQLKTDKKRLQQQQFKEWHQVLQLQSYNEEPLIVLPYVVLE
Length1570
PositionUnknown
OrganismDrosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Hawaiian Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.989
Instability index56.49
Isoelectric point5.35
Molecular weight177428.66
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25138
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     256.28|      58|      58|    1026|    1083|       1
---------------------------------------------------------------------------
  641-  706 (55.24/19.29)	NSNNN........NNNELNSEtvEDHR.ERGQQQQ......T....EsinrnidNQQKKLTA.......................AADADVTKImPTSIAPskPIKSI.
  966- 1002 (37.53/10.97)	NRTSN......RCNSSSNNSD.....................csnfS.......SQQTQNSI.......................NAKVRIRRT...............
 1003- 1056 (62.36/22.64)	..S..............EQVA..ERHVIERNRKKRrkanryE....Q.......EQQQQLSI.......................NEKPRIKRI.KIAING..QLPHIS
 1057- 1100 (56.34/19.81)	NYSSS......SCNNSSDEQD..EQREEEQDQNEQ....qeE....Q.......NEQQQEEQ.......................GEQKR...................
 1214- 1287 (44.82/14.39)	NISPNivvavvKTQNDADNSE.......................gvQ.......KEQQQMTQqatmaatpsclhnvercyryrrrHHRHRYRRP.PIDIT....LKHLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     110.63|      26|      26|    1123|    1148|       2
---------------------------------------------------------------------------
  734-  763 (36.21/24.31)	NEPNELKSTTTnevnNL.HSVVDLQMESDPG
 1121- 1146 (39.03/26.93)	ETRNKLSNDCQ....RM.LQTVASEDEEDDD
 1147- 1173 (35.39/23.54)	DERASLRSRST....TLdEDAVVLEHEYDND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.86|      18|      18|    1367|    1384|       3
---------------------------------------------------------------------------
 1367- 1384 (31.36/16.91)	DYENDEQLCLNTDDDEEE
 1388- 1405 (26.49/13.07)	DESEDEAVAAGEEEDEGK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.46|      24|      61|     106|     165|       4
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  131-  157 (37.72/79.14)	SSFmpeASNFSLNHLDNSVDFSSFKPK
  192-  215 (44.75/10.09)	SSF...ASASSQQQPQQQQAFPAFYPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     263.92|      78|      83|     441|     523|       5
---------------------------------------------------------------------------
  441-  488 (61.02/23.45)	................................VKTTKELFNDIQ.SRKLSIS.....YRGDSALPASASVSAAASKLNNRDARPTS
  492-  569 (111.62/57.82)	ETSLHSPhnLETFSTNASQLGNDKFSTILEASVHTDSETLTSAEpSRRHSLE........DSNSNNSQQTISATSRLINTECDHDA
  570-  635 (91.29/37.08)	ESRTHSP..LSRMNLNHSAGGNYDVSNQLMQLIRS...LNAP......LSVSeterlYRSQ.IVPCTCLIFEDAPKLN........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.44|      13|      16|     244|     256|       6
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  244-  256 (23.33/13.31)	LKDDLPLQMPRSI
  261-  273 (21.11/11.23)	LAQQQPQQLGRKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.25|      10|      16|     158|     168|       7
---------------------------------------------------------------------------
  158-  168 (14.72/13.48)	SDiDKSNEPPI
  176-  185 (17.53/ 9.90)	SD.ENENEARI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.10|      16|      26|     327|     343|      10
---------------------------------------------------------------------------
  327-  343 (26.63/19.11)	NPPPVSVNgQKKPEPEQ
  356-  371 (25.47/12.58)	NDSSNSVS.RLSPFEEQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.02|      18|     242|      55|      74|      19
---------------------------------------------------------------------------
   42-   59 (28.34/23.22)	TKEQLEATRLAKYINQLR
   62-   79 (29.68/16.16)	TKNDQLARRAKSLLKKWR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25138 with Med26 domain of Kingdom Metazoa
Unable to open file!