<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25130

Description GH24808
SequenceMACALLCWCWVVGGVGINCCLWAWVRPTTKVPAKKRATELASKKEKPCPTRMDEVINNHIDDAINSVILAVHASLPQDEEEELQQQQQLQLLLHKQQQQQQQQQQQQQQQQLPPTTVMPNAGVLFSTAATVAAVPARNPAPKKRSMRSKTIDCRSALLLLPTAVATAQTPTVPLMSAMQCIQLPSNGQLVQLAAEQPPLPSPIATPKVATPAPEVEEKPSMCQRQVLLASEVQLQPVMTTTAAAAAVAEALVVPTPATTAATVGAEAPTKIATATVAAVAATVAAVSTPTEVTRNNSCSLGRCEASNGCVCHLSGTTNSTSNNNNITNNNNSNNEKQKCHAQLAAGGAQLLAPAAEVEPDPEPELVTEKETKLESEPETEAKPKPELESQPQLVREPDPKPDPEPEAEPTPPPKEDVKKKQRRRRKNELAAIVADQLLESFKIDNARRDNLKKLENLAYEKSEDLLLTGMLLMSSTKRNATLQQQQQHPAVAAAATVAAVESKRSKVEFEQTPPAATGRGRPKRRQSCYYKRGRGKATPLGAETNISALKSSLESFSIGIEKQLLAKEAAAAAAAKAATPTASCILRPSILCTAAKEHQQQQKQQQKQQQKQQQTQQRQQQEQQQQQQQDQEQQQEQEQEQQQQEQQQQHLQSAAAATTIAATYSRDPRLNKNIHKEAAQEQLEHRQQQQQHSHQQQKQQLSQQEQNHQQQQQQEQPQPGEDLEEEDNYLTEIAKNVNDKIMSANNEDFEFAHDEFDQDKSHDPDQDKFYRPPTSMSVRSAPNLNDENSNFGSDDENTNTEIMDMDLDDEMSVYTSYSQDLGRTGRGRRRRRRRSVLLTRRPKKRNTRSSQQLEDADKFACQLCGKSFFTSTSLSKHNMTLAHVSKLSELEYMQSKSNAPPSPPQQQQVEAVVAPLQQTQQQQQQLRASVLISPVVHPQTIVIGAASSHVITEESLRLHDTQQQQQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHASQHSSPIHSAARLNLNPDERLFYECCNILKSAETPRLPTATAMPTIAVATPSVIVSAGVRKPLSELTIPVATTAEPASPPTCRPPRPPPPASPSPSPSPPQSPLPTTTTTIPTAAAATRIVPASSASATTVSHQPVIQQLFRNPPAATPTSTPTNHHHHQQQQHHNQHGQHHHHHVEQQQQQHHHHHQQQQQQQHHHHHHHQSHRLSPNYSMSQFSSMTATNMTQSRFKTKAAMKGYETNLELDMELAKSANRAVCKLTELADIALGSEKPPGVNYSPNQVSTPLSPVAVAATDHQQQQQQLLQQSHQQQQQLQPVTATGVEQSSTSSKTIMHGSSIIKATAATAAASSATLPPVSGRIIIPERPFKNIGLEEKAPITFQKPKASVNLLTDDNSVSTASYSDRDDYDFGTLSCEDVDVDAETDADAVAETVKLAEQQRQRQQLQLQQQQQLKQSSGVIACSAATSSTSSSSSSTASSTQQSSSSNSSRATAKTFENKSLIMGRIFKSKAKATTAAAAAATAAAATVTPGAIATLGATGATGTPVKSAPKDKAQLDQLFDELRGATAKPQQPVIELAPITATAPTPNSTPDPWLAPDVPALSATSASAPAMKATAATKKKITTKAATAAAAGPDRKKTAAGSAKAKIKTTARKPTKDLSKLQSELGMSTAEIEQLIDEGQRKSKRRCATNRPKKLVETWSSDEYEEFLSTKDIIALIEQKEQQEQRRKRKTSEAASQQELLPERPNLTQPLNNAKSKRNRKAHKDQVEQLQQQQEPQPPAPAPAPSKRSRQLRAAVDIQVEAPPPPPPPPTKTTKATRGKPAARTAKATKATKTPAAVGRKRGKQLEELQLEAEPEPEPEPATATIVATAAPTVQQQRLERSSQRTRSSRQQQQQQQQQQQRVVEASAEVASAEQQPRDMNHYQESHEKAASSVNVKQKPRGSSNNNVNKINNNNNSNRGSVATATTAAPTAAANATTNNNNNSSSSNKNLKTKRKSQSNRQSPARRKRPASEKQLYYWSSSSDDEFGRINVDAEAAEAEAGTQADAAVSAVATNEPQQQQQQQQQQQQQQQLLAPTKHFDDSEQYQKHGWIVGDSHKKLVKLLAIAKGNKKVDNCGVKRRTPKRKC
Length2127
PositionKinase
OrganismDrosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Hawaiian Drosophila.
Aromaticity0.02
Grand average of hydropathy-0.909
Instability index73.31
Isoelectric point9.10
Molecular weight233006.56
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25130
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     265.89|      16|      16|     616|     631|       1
---------------------------------------------------------------------------
   96-  111 (39.44/12.90)	QQQQQQQQQQQQ...QQQQ
  620-  637 (29.85/ 7.93)	QQEQQQQQQQDQ.eqQQEQ
  688-  706 (28.23/ 7.08)	QQQQHSHQQQKQqlsQQEQ
  966-  980 (35.54/10.88)	QQRQQQQQQQ.Q...QQQQ
  981-  996 (39.44/12.90)	QQQQQQQQQQQQ...QQQQ
 1182- 1197 (35.80/11.02)	QQHHHHHQQQQQ...QQHH
 1298- 1313 (30.80/ 8.42)	QQQQQLLQQSHQ...QQQQ
 2058- 2070 (26.80/ 6.34)	...QQQQQQQQQ...QQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.67|      22|      22|    1769|    1790|       2
---------------------------------------------------------------------------
 1769- 1790 (36.82/10.84)	QLQQQQEPQ...PPAPAPAPSKRSR
 1791- 1815 (34.86/ 9.87)	QLRAAVDIQveaPPPPPPPPTKTTK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.31|      19|      22|    1070|    1090|       3
---------------------------------------------------------------------------
 1070- 1090 (33.24/13.40)	PVATTAEPASP.PTcrPPRPPP
 1094- 1113 (33.07/ 9.14)	PSPSPSPPQSPlPT..TTTTIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.84|      17|      22|     370|     391|       4
---------------------------------------------------------------------------
  370-  386 (30.06/15.51)	ETKLESEPETEAKPKPE
  398-  414 (35.78/ 9.90)	DPKPDPEPEAEPTPPPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.07|      21|      22|    1603|    1624|       5
---------------------------------------------------------------------------
 1603- 1623 (34.78/18.22)	ATSASA.PAMKATAATKKKITT
 1626- 1647 (31.28/16.82)	ATAAAAgPDRKKTAAGSAKAKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.61|      21|      22|    1875|    1895|       6
---------------------------------------------------------------------------
 1875- 1895 (36.09/17.53)	QQQRLERSSQRTRSSRQQQQQ
 1899- 1919 (34.52/16.41)	QQQRVVEASAEVASAEQQPRD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     139.21|      22|      22|     248|     269|       7
---------------------------------------------------------------------------
  248-  269 (36.36/15.41)	AEALVVPTP...ATTAATVGA.EAPT
  272-  290 (24.34/ 7.61)	ATA....TV...AAVAATVAAvSTPT
 1117- 1137 (28.32/10.19)	AATRIVPAS...SASATTV.S.HQPV
 1138- 1155 (27.66/ 9.76)	IQQLFRNPP.......AATPT.STPT
 1522- 1544 (22.52/ 6.43)	AAAATV.TPgaiATLGATGAT.GTP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.24|      45|     278|    1550|    1598|       9
---------------------------------------------------------------------------
 1314- 1336 (25.23/ 7.22)	............................L...QPVTATGVEQSSTSSKTIMHGS
 1348- 1383 (35.59/15.17)	ASSATL....PPVSGRIIIPERPFknIGLeekAPITFQKP..............
 1550- 1598 (74.42/49.83)	KDKAQLdqlfDELRGATAKPQQPV..IEL...APITATAPTPNSTPDPWLAPDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.17|      11|     276|     642|     652|      10
---------------------------------------------------------------------------
  599-  610 (25.18/ 8.48)	QQQQKQQQKQQ
  642-  652 (22.98/ 6.99)	QQQEQQQQHLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     137.86|      40|     279|    1722|    1762|      12
---------------------------------------------------------------------------
  826-  849 (34.85/14.66)	.RGRRRRRR.........RS......VL.LTRRP........KK..RNTRS
  852-  898 (40.41/18.22)	QLEDADKFAcqlcgksffTSTSLSKHNMtLAHVSKLSE.LEYMQSKSN...
 1722- 1762 (62.61/36.92)	QQEQRRKRK.........TSEAASQQEL.LPERPNLTQpLNNAKSKRNRKA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.45|      15|      15|    1462|    1476|      13
---------------------------------------------------------------------------
 1462- 1476 (24.57/13.91)	SAATSSTSSSSSSTA
 1478- 1492 (25.88/15.14)	STQQSSSSNSSRATA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.88|      15|      15|     183|     197|      14
---------------------------------------------------------------------------
  183-  197 (25.79/12.68)	LPSNGQLVQLAAEQP
  199-  213 (27.09/13.76)	LPSPIATPKVATPAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.35|      11|      22|     783|     793|      15
---------------------------------------------------------------------------
  783-  793 (20.32/14.86)	NLNDENSNFGS
  806-  816 (20.02/14.52)	DLDDEMSVYTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.30|      15|      21|    1222|    1242|      16
---------------------------------------------------------------------------
 1222- 1236 (24.48/21.51)	TNMTQSRFKTKAAMK
 1244- 1258 (23.82/ 6.80)	LDMELAKSANRAVCK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.99|      33|     876|     138|     181|      18
---------------------------------------------------------------------------
  138-  181 (48.76/40.66)	NPAPKKRSMRsktiDCRSALlllptavATAQTPTVPLMSAMQCI
 1015- 1047 (61.23/29.66)	NLNPDERLFY....ECCNIL.......KSAETPRLPTATAMPTI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.41|      26|     317|    1682|    1707|      22
---------------------------------------------------------------------------
 1682- 1707 (47.59/27.56)	KSKRRCAT..NRP..KKLVETWSSDEYEEF
 1998- 2027 (37.82/20.24)	QSNRQSPArrKRPasEKQLYYWSSSSDDEF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.59|      11|     517|     917|     927|      24
---------------------------------------------------------------------------
  917-  927 (20.81/ 7.50)	QQTQQQQQQLR
 1437- 1447 (19.78/ 6.68)	QQRQRQQLQLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.62|      50|    1271|     534|     595|      26
---------------------------------------------------------------------------
  534-  595 (65.28/50.14)	RGKatPlgAETNISALKSSLESFSIGIE..KQL..LAKEAAAAAAAKAATPTascilrpsILCTAA
 1818- 1871 (75.34/34.08)	RGK..P..AARTAKATKATKTPAAVGRKrgKQLeeLQLEAEPEPEPEPATAT........IVATAA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25130 with Med12 domain of Kingdom Metazoa
Unable to open file!