<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25129

Description GH24221
SequenceMSALLEELGQKLASATTIDDQKQQLNSTRCDDSNSSSVLEDIDVTNTSSSSTSSNSSTTSSSCSHGSGTDTDTGKGSSTGGSMDAARVSSSSIGSASIASSSESTNASSSVNSSGLGLVVDVDSNIGSSQELSHGYESKSVTELDSLEDTCGSMLKDADKMCKLCSSRLVMPRILSCLHVFCEDCLVSLLSNKEARSASSPAVSLSSTASCSSASFDGSEHQHRMHALLECPVCKQQTQLGSKGVKELTCDYIVTNILDLSNLESEHIPCTSCKSKEDAISRCNDCANFLCNGCDKAHKYMRCFENHQVVRIEDLQKNVQNDNKLIIHKPICCRQHINENLKYYCFTCQVPTCNDCLLSEHKGNDHHYETAVIADQAVRADLEQTIGDALKKAEYCNDAGSNLSSALTELQAQHDNVRQQIDDAYKSYKRMLELIRDQFLTELGRLHSERELKIMDLMQSLENNMGRLEQASQFGQRALDKANAVEFLLLKPVISAQCSYLVEQTPQSDANYQLHFECMPDKFERFAREMFGKFRTESTKYQQQATQPAVATAAAATPNGNATNANGNVIGNAMCGATPSPTATTPKQHSPPPVFLVHGGCHGVGVGLLPSGVGGSVGGGGGGGRSLAGAGSSANSSSVQGRLSSAAVFSPISLPSSLQSSFDGDTSVMTNFSMMSTLPPDSPQQLQPPLQQQQQQQQQQQQQQQQQQQQQQQQQALQQVQQQQQQQQQQQQQQQQQQQQQQQQHKQQHQQQQQQQQQVLHQQPQSLPVAQQMSTRQGIVQVPQPGGHVNLIAGQSNAAVNMGLSSLNGMGMNAGGQPPPFSMLEYNLSRLASLTENIPDNLNDALNVGSSNAAAVVAANDASGGPGVGGGVAGGGVGGGVVGAPSHQHQQAVIPASAVTPTQPITLADILSGDQRALNNLQALAKLGLNNNDFCMPAATSPNLQTLNPIVGGVEEMTLNNFHAVAQPGTTSVVTGRNKATPMQIRCKFGSLGTAKGQFNSPHGFCLGVDEEIIVADTNNHRIEVFDKMGALKFQFGVAGKEEGQLWYPRKVAVMHNNGKFVVCDRGNERSRMQIFSKCGHFMRKIAIRYIDIVAGLAVTAKGHIVAVDSVSPTVFVISEEGELVRWFDCSDYMREPSDIAIRDNDFYVCDFKGHCVAVFQEDGTFLYRIGNEKVTCFPNGIDISNAGDVLIGDSHGNRFHVACYSREGALQSEFECPHVKVSRCCGLKITSEGYVVTLAKNNHHVLVLNTLYVH
Length1255
PositionTail
OrganismDrosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Hawaiian Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.406
Instability index54.67
Isoelectric point5.76
Molecular weight135161.42
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25129
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     140.97|      14|      15|     692|     705|       1
---------------------------------------------------------------------------
  692-  704 (27.41/ 9.84)	...QQQQQQQQ...QQQQQ
  705-  720 (24.59/ 8.18)	QqqQQQQQQQQ...ALQQV
  721-  734 (34.28/13.88)	Q..QQQQQQQQ...QQQQQ
  735-  748 (32.64/12.92)	Q..QQQQQQQQ...QHKQQ
  750-  765 (22.05/ 6.69)	Q..QQQQQQQQvlhQQPQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     227.35|      48|      50|      31|      78|       2
---------------------------------------------------------------------------
   15-   67 (68.62/33.87)	ATTIDDQKQQL..........nstrcD..DSNSS..SVLEDIDVTNTSSSSTSSNSSTTSSSCS.HGS
   68-  118 (60.77/29.21)	GTDTDTGKGSS..........tggsmD..AARVS..S..SSIGSASIASSSESTNASSSVNSSG.LGL
  119-  181 (55.26/25.93)	VVDVDSNIGSSqelshgyesksvtelDslEDTCG..SMLKDADKMCKLCSSRLVMPRIL..SCL.HVF
  182-  219 (42.70/18.47)	CEDC..............................lvSLLSNKEARSASSPAVSLSSTASCSSASfDGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     289.33|      52|      53|    1038|    1089|       3
---------------------------------------------------------------------------
  951-  989 (44.22/26.71)	.........VGG...VEEM.TLNNFH..AVAQP.....GT.T.S.VVTG.R.NKATP...MQIRCKF.....
  991- 1030 (34.06/18.61)	.........SLG...TAKG.QFNSP......HGfclgvDE.E.I.IVAD.TNNHR.....IEVFDKMG....
 1031- 1084 (82.17/57.00)	..ALKfqfgVAG...KEEG.QLWYPRKVAVMHN.....NG.K.F.VVCD.RGNERSR...MQIFSKCGHFMR
 1085- 1135 (51.89/32.84)	KIAIRyidiVAGlavTAKG.HI.....VAVDSV.....SP.TvF.VISE.EG.ELVR...W..F.DCSDYMR
 1137- 1168 (36.72/20.73)	........................PSDIAIRDN.....D....F.YVCDfKGHC......VAVFQEDGTFLY
 1169- 1219 (40.27/23.56)	RIGNE...kVTC...FPNGiDISNAGDVLIGDS.....HGnR.FhVAC......YSRegaLQSEFECPH...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.82|      19|      21|     637|     655|       4
---------------------------------------------------------------------------
  626-  644 (27.85/12.45)	SLAGAGSSANSSSVQ....GRLS
  645-  667 (26.97/11.83)	SAAVFSPISLPSSLQssfdGDTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.10|      20|     253|     599|     624|       5
---------------------------------------------------------------------------
  599-  619 (35.94/28.58)	GGcHGVGVGLLPSGVGGSVGG
  864-  883 (40.16/15.52)	GG.PGVGGGVAGGGVGGGVVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.70|      13|      20|     270|     283|       6
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  270-  283 (21.20/16.33)	CTSCKsKEDAISRC
  291-  303 (28.51/17.45)	CNGCD.KAHKYMRC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.59|      15|      54|     781|     799|       7
---------------------------------------------------------------------------
  781-  799 (19.95/16.82)	QVpqpgGHVNLIAGQSNAA
  801-  815 (24.64/ 9.87)	NM....GLSSLNGMGMNAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     122.92|      32|      32|     408|     439|       9
---------------------------------------------------------------------------
  376-  395 (24.57/10.92)	...QAVRADLEQTIGDALK..........K.AEY
  408-  439 (55.19/32.55)	TELQAQHDNVRQQIDDAYKSYKR.MLELIR.DQF
  441-  474 (43.16/24.05)	TELGRLHSERELKIMDLMQSLENnMGRLEQaSQF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.87|      21|      41|     530|     550|      11
---------------------------------------------------------------------------
  530-  550 (36.56/17.81)	MFGKFRTESTKYQQQATQPAV
  574-  594 (40.31/20.29)	MCGATPSPTATTPKQHSPPPV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25129 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ANGNVIGNAMCGATPSPTATTPKQHSPPPVFL
2) LLPSGVGGSVGGGGGGGRSLAGAGSSANSSSVQGRLSSAAVFSPISLPSSLQSSFDGDTSVMTNFSMMSTLPPDSPQQLQPPLQQQQQQQQQQQQQQQQQQQQQQQQQALQQVQQQQQQQQQQQQQQQQQQQQQQQQHKQQHQQQQQQQQQVLHQQPQSLPVAQQMSTRQGIVQVPQPGGHVNLIAGQSNAAVNMGLSSLNGMGMNAGGQPPPFSMLEYNLSR
3) MSALLEELGQKLASATTIDDQKQQLNSTRCDDSNSSSVLEDIDVTNTSSSSTSSNSSTTSSSCSHGSGTDTDTGKGSSTGGSMDAAR
565
608
1
596
830
87










Molecular Recognition Features






MoRF SequenceStartStop




NANANA