<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25124

Description GH18669
SequenceMEVDQPTLADVVFVIENSAINGAYLNELKTNYILPTLEHFTQGSIDEREFLIAERYSTLYGIVTYRTASNLLEPVCSTYGPFVQPQKVIETIERLPLVGGGMESHAHMSEGFAAAHGCFDEMNKQRYMLEQSNLQRHCILICNSPPYQMSVNESWKYKGKSCEQLAALFNERKINLSIIAPRKMPVLFKLYMKADGDQPITTKNYAKNIRHLVLLKGYSLKERAPSPNSNGPALPQHAMGAPQAQATAVNNNPGGQQAQPMETTPAQQQQPVGPQQQQQQQQQQVMNMNAIQQQQQQQQQPQPQPNAAAQAGLLNAQQQQQLLQQQQQQQQQQQQQNQFVPNTMQNTNFQQNVVPGQNRWMYPNQPGVRPAFMQNAGNNMPLQQNQNPNSALISRINAPPNQTVNALQQQQLQQQQQQQQQRLQMLNHQQFNQLQQQLAQQQQQQQQQQQQQHPQQQQQVNPNANTNMMPTVSNAANVPSLQQASAPQQQQQQPNQQQQLQQQQQQQPQEQASLREKIWTGVLEWAEKAKNDQQKIPHSLQCTVCTNIKDGEPEIKADNWPPKLLMQLMPKHLVGNIGGQFLKDSKMVVFRPTPGEALDSLAKMMTNGFAGCVHFSALPNTPTCDIKVLILLYTPDRNAFLGFIPNNQSMFVERLRKVIQQKQSHGNMQQQQQQQQQQQQQQMPPQQQMQQMMQQGKTPMELQQQQQQQQMQQDNSQQQQPHYNQYAQLNMQMGGGPGGNGAGGMPMQPQMQMNMMQQQQQQQQQQRMPLGVPVANPNLQQQLQQQQQQQVPQQQQQQQQRMVRPMLGNNNPGLRQLLQHQAPGNQFRPQMGGQPNQMGAGGPMVGNRNFDDGGYEFM
Length858
PositionUnknown
OrganismDrosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Hawaiian Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.984
Instability index71.30
Isoelectric point8.95
Molecular weight97585.72
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25124
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     205.04|      31|      31|     397|     427|       1
---------------------------------------------------------------------------
  260-  287 (46.93/ 7.87)	PM.ETTPAQQQQPVGP..QQQQQQQQQQVMN...
  310-  340 (52.88/10.27)	QA.GLLNAQQQQQLLQ..QQQQQQQQQQQQNQFV
  400-  430 (59.72/13.04)	PN.QTVNALQQQQLQQ..QQQQQQQRLQMLNHQQ
  777-  805 (45.51/ 7.30)	PNlQQQ..LQQQQQQQvpQQQQQQQQR.MVR..P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     253.46|      45|      53|     433|     477|       2
---------------------------------------------------------------------------
  436-  482 (84.98/19.40)	QQLAQQQQQQQ.......QQQQQQHPQQQ..QQVNPNANTNMMPTVSNAAN.....vpSLQ
  483-  541 (59.13/10.66)	QASAPQQQQQQpnqqqqlQQQQQQQPQEQ..ASLREKIWTGVLEWAEKAKNdqqkiphSLQ
  666-  700 (51.03/ 7.92)	GNMQQQQQQQQ.......QQQQQQMPPQQqmQQMMQQGKTPM...................
  703-  740 (58.32/10.39)	....QQQQQQQ.......QMQQDNSQQQQ..PHYNQYAQLNMQMGGGPGGN..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.99|      17|     463|     288|     305|       4
---------------------------------------------------------------------------
  288-  305 (30.69/10.00)	MNAIQQQQQQQQQpQPQP
  753-  769 (37.30/ 9.76)	MNMMQQQQQQQQQ.QRMP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.29|      16|     251|     565|     580|       5
---------------------------------------------------------------------------
  565-  580 (31.05/14.37)	LMQLMPKHLVGN.....IGGQ
  814-  834 (25.24/10.31)	LRQLLQHQAPGNqfrpqMGGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.79|      14|      25|     186|     199|       6
---------------------------------------------------------------------------
  186-  199 (26.18/15.45)	VLFKLY.MKADGDQP
  213-  227 (20.61/10.74)	VLLKGYsLKERAPSP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25124 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GYSLKERAPSPNSNGPALPQHAMGAPQAQATAVNNNPGGQQAQPMETTPAQQQQPVGPQQQQQQQQQQVMNMNAIQQQQQQQQQPQPQPNAAAQAGLLNAQQQQQLLQQQQQQQQQQQQQNQFVPNTMQNTNFQQNVVPGQNRWMYPNQPGVRPAFMQNAGNNMPLQQNQNPNSALISRINAPPNQTVNALQQQQ
2) QQQQQRLQMLNHQQFNQLQQQLAQQQQQQQQQQQQQHPQQQQQVNPNANTNMMPTVSNAANVPSLQQASAPQQQQQQPNQQQQLQQQQQQQPQEQAS
3) RLRKVIQQKQSHGNMQQQQQQQQQQQQQQMPPQQQMQQMMQQGKTPMELQQQQQQQQMQQDNSQQQQPHYNQYAQLNMQMGGGPGGNGAGGMPMQPQMQMNMMQQQQQQQQQQRMPLGVPVANPNLQQQLQQQQQQQVPQQQQQQQQRMVRPMLGNNNPGLRQLLQHQAPGNQFRPQMGGQPNQMGAGGPMVGNRNFDDGGYEFM
217
417
654
411
513
858










Molecular Recognition Features






MoRF SequenceStartStop




1) NQYAQ
724
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