<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25115

Description GH21275
SequenceMDTQILDAVNDFLKVDSIDEAFVSVIVFKSDDDKASSFANSLITAFGNVENREQVVRSYLLRAAEAPSYHMQVLMGALPKLVDAHLITARMLCDKVLSCEKLDYERKTFWIESFRLIKKVIAQVDYKGVREIMKACRDKAQWFPLNVNVTYLPQLLAVEEIIRFIFDRNNCLLPAYFIANEIMRPFPYHWKLNQLMTDFVEEFRTTAQMVSIIGHANMLPIVEHFGYADHLMNSWRLDHNTLKFNFKGSLPYEPELLEDQTPLLRYVLEQPYSREMVSVMLNLQKHQKQRYNALEEQLVNLIIHAMEMTETNDATAGSGFNASDEQISPNEWVWLHLSSQLIYFVLFQLVSFMHIVMALHDKLSKLELRKGRDQLMWILLQFISGSIQKNPITNFFPVFRLFDLLYPEQEPLKLPDYNKSSLVRHMAPICIWIHLMKKARVENMNITRPLPIALKNHQDFLQHLVAPNSMMNVTLGNDFRIILICNAYSTNQEYFARHMNILLDAMNGNAKSANGTPIPAVTYSVSVLDSLTLHSKMSLIHSFVTQMLKQAQSKTLVPAPALIETYARLLVYTEIESLGIKGFLTQLLPTVFKNHAWAMLHTLMEMFSYRLHHVPTHYRVQLLSLLYSLSSVPQTNKMQLNLCFESTALRLITSIGSAEFQSQFSRHLNDKSPGGVASNESEELNRVLILTLARSMHVHGGGDELAGWCKDFLSNIMQHTPHSWPLQSLACFPPALNEYFTQNNHPAENKQQLKKSVEEEYRNWTSMSNENDIIAHFLRPNTNPLFLCLLFKIIWETESISPVAYKILEGISARALSTHLRKFCDYLVAEVASSSDGRDFIHKCVDTINNMIWKFNVVTIDRLVLCLALRTHEGNEAQVCLIIIQLLLLKATELRNRVQEFCKDNNPDHWKQSNWHEKHISFHQSFPEKFAPDESASQIPLPVYFSNVCLRFLPVLDVVVHRFIELTIPNVLQILCIILDHLSILYKFHDRPITYLYNTLHYYERILRDHLVVKKKLMSAITSAFSEIRPANWSVSDPYKVYLQGQDTLWTPELSYYMNLIRRLADTISGKNVFYTTDWRFNEFPNAPTHALYVTCVELLGLPLAPSVVAGSIIDVIVDGYAVIPQKEIHSYINAVGIVLAALPEPYWSAIYERLQDMLNTPNMLNWTYRFNAFELFNFKTVREAMLEKSYAVVLAVAHAVFHHMGAFKLAAMTRYIKEKLKPCVRTEHQLLYLCHVFGPFLQRIEQEKPNAVAGIAIFLYEMLETVDKQHGPKPLEYMDQICDFLYHIKYIHVGNIIKNESEAIIKRLRPLLQMRLRFITHLNLEDIHNEKSADGNANSTTNSNANANQSPLQPQQQQQQQQQQQQQAQTAPVAAATTSVPLGSGGNQQMYLQHMQQQQQQQQQQQMQSMGMRHN
Length1416
PositionTail
OrganismDrosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Hawaiian Drosophila.
Aromaticity0.10
Grand average of hydropathy-0.125
Instability index43.37
Isoelectric point6.76
Molecular weight163273.80
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25115
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.03|      13|      35|    1356|    1368|       1
---------------------------------------------------------------------------
 1356- 1368 (28.21/16.89)	QQ......QQQQQQQQQQQ
 1389- 1407 (21.81/11.86)	QQmylqhmQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.79|      19|      35|     456|     477|       3
---------------------------------------------------------------------------
  456-  477 (29.91/25.64)	NHQDFLQHLvapNSMMNVTLGN
  491-  509 (34.87/20.85)	NQEYFARHM...NILLDAMNGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.34|      37|      38|     511|     548|       4
---------------------------------------------------------------------------
  511-  548 (59.32/43.22)	KSANG.TPIPAVTYsVSVLDSLTLHSKM.SL.IHSFVTQML
  549-  588 (48.02/29.84)	KQAQSkTLVPAPAL.IETYARLLVYTEIeSLgIKGFLTQLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.93|      10|      35|    1195|    1208|       5
---------------------------------------------------------------------------
 1195- 1208 ( 9.39/16.13)	LAVAHaVFhhmGAF
 1232- 1241 (22.54/11.74)	LYLCH.VF...GPF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.13|      21|      26|     949|     973|       7
---------------------------------------------------------------------------
  949-  973 (32.98/30.57)	C..LRFLPVLdvvvHRFIELTIP...NVLQ
  976- 1001 (30.16/17.84)	CiiLDHLSIL....YKFHDRPITylyNTLH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.25|      35|      37|     710|     746|       8
---------------------------------------------------------------------------
  710-  746 (61.10/42.30)	KDFLSNIMQHTPHSWPlqSLACFPPALNEYFTQNNHP
  750-  784 (60.16/35.74)	KQQLKKSVEEEYRNWT..SMSNENDIIAHFLRPNTNP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25115 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IHNEKSADGNANSTTNSNANANQSPLQPQQQQQQQQQQQQQAQTAPVAAATTSVPLGSGGNQQMYLQHMQQQQQQQQQQQMQSMGMRHN
1328
1416










Molecular Recognition Features






MoRF SequenceStartStop




1) NQQMYLQHMQQQQQQQQQQQMQSMGMRH
1388
1415