<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25110

Description GH15494
SequenceMKENNKILQLINVAWRERWSDSQWGINIKKVLPRGVSGDVYNLADCLLQQAVIGSTANPLVLNYLKHSLCAHLVSHAAVLRCIAKYDKLGRVYCVTALLEFLVSIIDGITCRIKSEETLLPGAMVQLVLWIMQIFARTLQQYEMRGELSAEQSYMLDQSCLLVEHLTKQQFALAMLNVGCHEEVDSLDKMRELYASIKGSLTNSNFTLSSATAEQQLKQLAYIDAKQLELQSLNPLPSAEKISCCVQPLLAVEVLLNPCKDTSYYVAELQMLQRLKGYTNTRLFYEIIRAGFLTLSNVADTSPDTMWGAFMLFKMPHIIKQLHTLQRVPGEQPLPPTDYIPELVEALELLIEDNLLLDFMATKCSCNIIDFLLNDWTKQQLVNDVHVKKFASQREAASLLLKKCVNGQQTPSNINYIKRAEVPLSGVLKTLCTNKVQDMVNVLCQVPVGNNFELILSVATVEGLLKTFVSRLIQCNENSKQVPGELGKLSVIRSTLFDVSFLMLTSIVQTYGSDVVLSERGDSFFEKWVRECMMERNKLKNPRQILALCDDSIVDELLLSLSKPEAAAQLKQPSSLTWQDICLNLPGVLHHVLIAWEQETLSSADVKSILDNMKRRLFSFSVCATSFLCAYMYSVRETELLKPLNMIQQFLAPLTTEELSSQENSKERLALSYQVIRKMQHDVHPAPNTKSRLISHTPLIEQFRECWRSVHDAGHLPVRAAQTLESLLLAGGASWLVTQLAEQLLSCKYMRDMAKCMDIVFAVMHLDIERSTEALLQYVVAPLILRRQGDDINEPQSLVLARLCVYCIISCLETRSLAAGALKKRSRSHDEDELLSTSAAKVRKVFSECSDNSNEAATNAVASMLVGGGTTPNTDLLRATPVNLKEPLHSSVKHIFRVFLQFVSGDELSPKAVFVYQFISLLVECGGERVAPVLRLLPPNLMQQLLKVLATDDIRVGLISRLYDLRAQSGRQAAVADLCLWRNMQLARHSIHL
Length993
PositionTail
OrganismDrosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Hawaiian Drosophila.
Aromaticity0.06
Grand average of hydropathy0.055
Instability index47.11
Isoelectric point6.73
Molecular weight111516.64
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblMetazoa

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:EnsemblMetazoa

GO - Biological Process
ecdysone-mediated induction of salivary gland cell autophagic cell death	GO:0035072	IEA:EnsemblMetazoa
pupal development	GO:0035209	IEA:EnsemblMetazoa
regulation of transcription by RNA polymerase II	GO:0006357	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25110
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.85|      42|     183|     453|     499|       1
---------------------------------------------------------------------------
  208-  252 (60.82/30.81)	LSSATAEQQLKQLAyidAKQLEL.QSLNPLPSA.EKISCCVQPLLAV
  456-  499 (59.03/44.48)	LSVATVEGLLKTFV...SRLIQCnENSKQVPGElGKLSVIRSTLFDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.86|      30|     183|     348|     378|       2
---------------------------------------------------------------------------
  348-  378 (49.24/35.45)	ELLIEDNLLLD...FMATkCSCNIIDFLLNDWTK
  531-  563 (44.62/27.23)	ECMMERNKLKNprqILAL.CDDSIVDELLLSLSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     196.44|      61|     193|     688|     788|       3
---------------------------------------------------------------------------
  726-  788 (98.71/149.91)	SLLLAGGASWLVTQLaeQLLSCKYMRDMAKCM...DIVFAVMHLDIERSTEALLQYVVAPLILRRQ
  920-  983 (97.73/60.14)	SLLVECGGERVAPVL..RLLPPNLMQQLLKVLatdDIRVGLISRLYDLRAQSGRQAAVADLCLWRN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25110 with Med24 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA