<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25110

Description GH15494
SequenceMKENNKILQLINVAWRERWSDSQWGINIKKVLPRGVSGDVYNLADCLLQQAVIGSTANPLVLNYLKHSLCAHLVSHAAVLRCIAKYDKLGRVYCVTALLEFLVSIIDGITCRIKSEETLLPGAMVQLVLWIMQIFARTLQQYEMRGELSAEQSYMLDQSCLLVEHLTKQQFALAMLNVGCHEEVDSLDKMRELYASIKGSLTNSNFTLSSATAEQQLKQLAYIDAKQLELQSLNPLPSAEKISCCVQPLLAVEVLLNPCKDTSYYVAELQMLQRLKGYTNTRLFYEIIRAGFLTLSNVADTSPDTMWGAFMLFKMPHIIKQLHTLQRVPGEQPLPPTDYIPELVEALELLIEDNLLLDFMATKCSCNIIDFLLNDWTKQQLVNDVHVKKFASQREAASLLLKKCVNGQQTPSNINYIKRAEVPLSGVLKTLCTNKVQDMVNVLCQVPVGNNFELILSVATVEGLLKTFVSRLIQCNENSKQVPGELGKLSVIRSTLFDVSFLMLTSIVQTYGSDVVLSERGDSFFEKWVRECMMERNKLKNPRQILALCDDSIVDELLLSLSKPEAAAQLKQPSSLTWQDICLNLPGVLHHVLIAWEQETLSSADVKSILDNMKRRLFSFSVCATSFLCAYMYSVRETELLKPLNMIQQFLAPLTTEELSSQENSKERLALSYQVIRKMQHDVHPAPNTKSRLISHTPLIEQFRECWRSVHDAGHLPVRAAQTLESLLLAGGASWLVTQLAEQLLSCKYMRDMAKCMDIVFAVMHLDIERSTEALLQYVVAPLILRRQGDDINEPQSLVLARLCVYCIISCLETRSLAAGALKKRSRSHDEDELLSTSAAKVRKVFSECSDNSNEAATNAVASMLVGGGTTPNTDLLRATPVNLKEPLHSSVKHIFRVFLQFVSGDELSPKAVFVYQFISLLVECGGERVAPVLRLLPPNLMQQLLKVLATDDIRVGLISRLYDLRAQSGRQAAVADLCLWRNMQLARHSIHL
Length993
PositionTail
OrganismDrosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Hawaiian Drosophila.
Aromaticity0.06
Grand average of hydropathy0.055
Instability index47.11
Isoelectric point6.73
Molecular weight111516.64
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblMetazoa

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:EnsemblMetazoa

GO - Biological Process
ecdysone-mediated induction of salivary gland cell autophagic cell death	GO:0035072	IEA:EnsemblMetazoa
pupal development	GO:0035209	IEA:EnsemblMetazoa
regulation of transcription by RNA polymerase II	GO:0006357	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25110
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.85|      42|     183|     453|     499|       1
---------------------------------------------------------------------------
  208-  252 (60.82/30.81)	LSSATAEQQLKQLAyidAKQLEL.QSLNPLPSA.EKISCCVQPLLAV
  456-  499 (59.03/44.48)	LSVATVEGLLKTFV...SRLIQCnENSKQVPGElGKLSVIRSTLFDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.86|      30|     183|     348|     378|       2
---------------------------------------------------------------------------
  348-  378 (49.24/35.45)	ELLIEDNLLLD...FMATkCSCNIIDFLLNDWTK
  531-  563 (44.62/27.23)	ECMMERNKLKNprqILAL.CDDSIVDELLLSLSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     196.44|      61|     193|     688|     788|       3
---------------------------------------------------------------------------
  726-  788 (98.71/149.91)	SLLLAGGASWLVTQLaeQLLSCKYMRDMAKCM...DIVFAVMHLDIERSTEALLQYVVAPLILRRQ
  920-  983 (97.73/60.14)	SLLVECGGERVAPVL..RLLPPNLMQQLLKVLatdDIRVGLISRLYDLRAQSGRQAAVADLCLWRN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25110 with Med24 domain of Kingdom Metazoa
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