<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25093

Description GM16690
SequenceMDGNAQNMFHGNHQGDPYYRYDAAAAAAAAAAANPRAMGPPGGYPPRHRPPHPLQQQPQYPSYQPTAENLYGLGAADHQAAMGLGVGVGVGAGMGDLSGWGAAPSVPGQAAAYPGAGLGAYGHPQAAPPAQQQRQSNASAYRQHMPAYGQQDQQKLASYGAQQSMMAGYGSLAPQQQQQQQPPTPQQQQQAQQVQQQAQQQQQQQQSQQQLLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKISRDHSGLHNLVPRGRNGGKSNKESTGVSTPAPGSASGSNSGNTTPAHKSSALDGSDKDSGGINASAVAAAVTSIHDPNHWSKKEKYDADAYLEGAYKKHLGRHANKVLLRVRMLYYIQHEVIGDFVQQIKDNTPISQLLLTFKPFFWNHRNEDDANSKHDDGDEVDDDGTTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSSSENGSGGNDKTESENDATTVSESSSKSEVLPGKGSDLDVSVAQQDALSATLESANTSDPKINKNDAQVSASVSCDPADSSLSEAAGKAQGTGVQTGDAGELDIESEKKENEKETKESTADAPAVEVKKDSAAIARAEGDKTESCTNNATTNISTTTTTTTITNTTTTTNNPSSKAANSNNTTDHANSNSHLGLDEEESVAGSYPPTVAAVEDATTMWPSMQDLNTRLRRVITAYQRNYKKEELKLQQKAKLQALVSSTPPLSVPTTPTLQSMQMQLQSGSGSGGSGIGSSAQHDASGRSLQALMQSQGASTSAAAAAAASGAGGSCSGSGQVGMGGAGVMPAMPTAADISLMLSILNTTDVNQLANLDINKLAMYLVSMNNKMERQGKMELAAKERESQRLQLIPKKWNRREEYEFLRVLTGYGVDLHLSTSMGSTNGSSLSPDWTKFKQMAHLERKSDETLTDYYKVFVAMCKRQAGLKLTESERGLEGIIEEIEKEHAKLILDRLEVLAKLREVARNPMLEERLKLCTKNADTPDWWEPGRHDKELITAVLKHGLYRSETFIFNDPNFSFGESEKRFIRELEAQIQRTIKLEAFNAEKAEKLAAAEIAAATEKAAATEKATAEKAASVKNEVIDLDDELMTNESVIKKESPVTPIKEEIKSEESPEKQDTADILEDKNSDAEESTKIKDNADFNSEITDKEALDESTNLNKDKSSTEVPEIEDIKPSEEKMEVEEVPVAENGEEKEGAPEKCSDAEDKKLSEEKPSSPVVPDGKVSEMEADEVASNTEENCSGESESPEKGCEDKVVEKVEEEKGENSNKKAEEQKEETEKLEKSSLESEPSEKSETALEPEVAVPKKLTGDQDILDLVAGPSDPDDDEVMKEKEKAVEEECKKQAAELKARFPDLEVIQPATVKQQKLEKPKLEMCMIRWFKDFALERRIAHIVACVESGNWPVDSKYSAFATCKGATDLSIALHESIPHLSSLERRSTTPDVITITTDQGVTKHLQTSHMQQVASSASAASTSSGVPQVTQSKPSSSNSLPGLDAKSINAAVAAAVAAAAAGGNATSLSSLLPGMSLSAATGSSAGGVSGLSVPSAGSGVGKKRKRHIAIDVETERAKLHALLNSSTMAPKDWESEIANMEALSGSSGRGRGGNSSALSGMQPPPAHQHASLSRQSSGQFSKPAVPALKTPPPSMGAPMDLSSSLPKMNMTEMLKSASSSGAIDLSEVQDFSMPSKKSSVHAALSSAFPSMGSKSKLDDTLNKLMKKNNCTIEEPVIGKEKKRKKLDEIVLGLSAAKEQKTFPDPSLPSSKKPQIPPSVSVTPANLQSSSNQQSNQKPFTITVTTVPGKSKSGSSNSGSGTGGSSSASGGGAGGSVLSALQNMSMGGLSSKDSLNALLAQTMATDPQTFLKQQQKMMQFLPPAQRKAYENMLAEMEQAMKISSKFSTNSPHDVKVNKWLSDMTSPLGDQLSIDYVGGGGASGSGSGNSRRSNRQQGNSQQSSSAAQLQKQQQQQQQQQQQQHSMPGPQNLTGEEPVPVINKQTGKRLGGNKAPQLKRLMQWLTENPNYEVDPKWLEQMQNPMSAPSPKPPSMESSYGSSAVKSHGGRPSSNSSNTSSSSHTQQHQQSSAAQSQAGGNSGSSKKNSRQQTAASAALDQAALQFGSLAGLNPSLLANLPGLGAFDPKNPLAAFDPKNPLLSMSFGGMPGMGNIPGLGNLNNMNLFASLAGMGGLGNLAGMDTQSLAALMAAAGPTLGGLSGASGGAGSGKSQAQSQSSATSSSSSASKKKQQQQQQQAQNEAAQLAAAISASTAGSGASGGKNAAASASQLAAGFPFLFPNPSLLYPPMGLGGLNPYSLGSSGLGSAYDQLAQQYNLLNGATSSASNTSSTQSKSHQSQSKSSQSRNTTASANSAASLMNAMASMGGGASTVTTPSTSASGSGRGRQSSSRNQSQTTPTAADMAQLSSLLMPGADPHLLESLSRMSNMDLAQATRLMSSLGMPPLSGTPSSSGGGNTSTSKRSSQAANEANAQAKEQQKWFESLARGALPTDLAALQAFSQGKMPSTSGSNTGTSTSSSKSSKAAAAAAAAQLPQIPGMSSDFPQAFLAEMAAQAMAAAGGSLPLSGPGSLASLAGLTGGSAGGGGGSSASASTSHSSSKRQREQDAFKQQMDYYTKTLGLGSGISLIPTSSAGGSSASSSTANAAAAAYAAALDAEQQHQQQQKALSKRSRGDIHPTKEELAAAALAAGLPLNLGASMSSIEKSLRGGSSSSSSSTPAPMSAEQDKVTLTPLNASGGGSGSSSSSAAAAGLAANLPSQTTITIAPPISSGASTSSERSERSESRISLTITNAADAAKLPPPYEEADELIIQPILKKPTAANPGSSHGGSVDDLDTAENTSAANLSGSSSSSAAAAAAAAAAAEENRRSSNRLKRPRSGNEQGSGSVEGQPPEKRRELRSTRHTRSSADASTLNLSTGSESGAEERNE
Length2936
PositionKinase
OrganismDrosophila sechellia (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.03
Grand average of hydropathy-0.645
Instability index55.34
Isoelectric point5.68
Molecular weight306554.63
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:EnsemblMetazoa

GO - Biological Function
GO - Biological Process
axon guidance	GO:0007411	IEA:EnsemblMetazoa
blastoderm segmentation	GO:0007350	IEA:EnsemblMetazoa
determination of adult lifespan	GO:0008340	IEA:EnsemblMetazoa
heart development	GO:0007507	IEA:EnsemblMetazoa
imaginal disc-derived wing morphogenesis	GO:0007476	IEA:EnsemblMetazoa
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblMetazoa
neuron remodeling	GO:0016322	IEA:EnsemblMetazoa
positive regulation of border follicle cell migration	GO:1903688	IEA:EnsemblMetazoa
positive regulation of organ growth	GO:0046622	IEA:EnsemblMetazoa
positive regulation of receptor localization to synapse	GO:1902685	IEA:EnsemblMetazoa
regulation of synaptic growth at neuromuscular junction	GO:0008582	IEA:EnsemblMetazoa
segment specification	GO:0007379	IEA:EnsemblMetazoa
short-term memory	GO:0007614	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25093
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     148.52|      22|      22|     134|     155|       1
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  136-  155 (26.10/ 6.02)	SNASAYRQHMPAYGQQDQQK..
 1945- 1966 (32.72/ 9.52)	QGNSQQSSSAAQLQKQQQQQQQ
 2059- 2080 (29.47/ 7.80)	SSNSSNTSSSSHTQQHQQSSAA
 2081- 2101 (27.43/ 6.72)	QS.QAGGNSGSSKKNSRQQTAA
 2225- 2246 (32.79/ 9.55)	SSATSSSSSASKKKQQQQQQQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.93|      18|      22|    2147|    2164|       2
---------------------------------------------------------------------------
   93-  111 (24.45/ 8.00)	GMGDLSGWGAAPSV.pGQAA
 2151- 2170 (27.48/10.12)	SFGGMPGMGNIPGLgnLNNM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.65|      12|      22|     175|     196|       3
---------------------------------------------------------------------------
  175-  190 (20.69/14.60)	QQQQQQQpptpQQQQQ
  199-  210 (25.96/16.13)	QQQQQQQ....QSQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     759.36|     112|     112|    2506|    2617|       4
---------------------------------------------------------------------------
 1503- 1551 (47.28/ 8.59)	AAA..VAAAA.....AGGN....ATSLSS....LLPGM.S.LS.......AAT...GSSAGG...............V.SGLSVPS.........................AGSGV.............G...............................................................................................................................................
 1797- 1847 (42.11/ 6.90)	....................................................P...GKSKSGS........SNSGSGT.GGSSSAS.........................GGGAG.............GSVLSAL.QNM.SM...GGLS...SK............................DSLN..........AL..........................................................................
 2182- 2266 (47.97/ 8.82)	................LGN....LAGM.....DTQ....S.LA.......AL....MAAAGPT...L............GGLSGAS.........................GGAGS.............G..............................................................................................ksqaqsqssatsssssaskkkqqqqqqqaqneaaqlaaaiSASTAGSGA
 2267- 2402 (102.65/26.70)	SGG..KNAAA.....SASQ....LA...AG..F..PFL...F.................PNPS...L.LYPPMGLGGL.NPYSLGS.........................SGLGSaydqlaqqynllnGATSSASnTSSTQS...KSHQ...SQskssqsrnttasansaaslmnamasmggGA..............ST....V..T...TPSTSASGSGrG........................................RQSSSRNQS
 2403- 2472 (49.94/ 9.46)	QTTptAADMA.....QLSS..llMPG..AD....PHLLES.LSrmsnmdlAQAtrlMSSLG....................................................................................................................................................mppLSGTPSSSGG.G........................................NTSTSKRSS
 2473- 2531 (87.48/21.74)	QAA..NEANA.....QAKE..............QQKWFES.LA.................RGA...L....PTDL.........................................................................A...................................ALQ..........AFSQ....G..K...MPSTSGSNTG.T........................................STSSSKSSK
 2532- 2653 (167.78/48.00)	AAA..AAAAA.....QLPQ....IPGMSSD..FPQAFLAE.MA.......AQA...MAAAGGS...LPLSGPGSLASL.AGLTGGS.........................AGGGG.............GSSASAS.TSHSSS...KRQR...EQ............................DAFKqqmdyytktlGLGS....GisL...IPTSSAG..G.S........................................SASSSTANA
 2654- 2797 (108.99/28.77)	AAA..AYAAAldaeqQHQQqqkaLSKRSRG..DIHPTKEE.LA.......AAA...LAA.G.....LPLNLGASMSSIeKSLRGGSsssssstpapmsaeqdkvtltplnaSGGGS.............GSSSSSA.AAAGLA...ANLP...SQ............................TTI.......tiapPISS....G.......ASTSSERSE.R........................................SESRI.SLT
 2798- 2916 (105.16/27.52)	ITN..AADAA.....KLPP.....PYEEADelIIQPILKKpTA.......ANP...GSSHGGSvddLDTAENTSAANL.SGSSSSS.........................AAAAA.............AAAAAAE.ENRRSSnrlKRPRsgnEQ............................GS................gsveG..Q...PPEK..RREL.R........................................STRHTRSSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.58|      24|      28|     426|     452|       5
---------------------------------------------------------------------------
  426-  452 (35.19/24.62)	GGDNKDSLLDPErpsSSGKSSSENGSG
  457-  480 (38.39/18.81)	TESENDATTVSE...SSSKSEVLPGKG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     244.35|      46|      47|    1167|    1212|       6
---------------------------------------------------------------------------
 1072- 1112 (33.53/14.33)	.........KAASVK.NEVidldDE.LMTNESVIKK.E....S.P...V.............TP............IKEEIKSEES
 1113- 1161 (43.52/21.11)	PEkqdTADI..LEDKnSDA....EEsTKIKDNADFN.SE...I.TDK.E.............AL............DESTNLNKDK
 1167- 1212 (78.53/44.85)	PE...IEDIKPSEEK.MEV....EE.VPVAENGEEK.EG...A.PEK.C.............SD............AEDKKLSEEK
 1216- 1274 (43.68/21.21)	PV...VPDGKVSE...MEA....DE...VASNTEENcSGeseS.PEKgC.............EDkvvekveeekgeNSNKKAEEQK
 1275- 1332 (45.09/22.17)	EE...TEKLEKS..S.LES....EP.SEKSETALEP.EV...AvPKK.LtgdqdildlvagpSD............PDDDEVMKEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.35|      16|      24|    1612|    1627|       7
---------------------------------------------------------------------------
 1612- 1627 (28.18/13.81)	QPPPAHQHASLSRQSS
 1639- 1654 (27.75/13.46)	KTPPPSMGAPMDLSSS
 1655- 1670 (24.42/10.70)	LPKMNMTEMLKSASSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      46.02|      10|      15|     609|     618|       8
---------------------------------------------------------------------------
  586-  595 (14.68/ 6.83)	KTESCTNNAT
  609-  618 (16.73/ 9.16)	NTTTTTNNPS
  626-  635 (14.61/ 6.75)	NTTDHANSNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.55|      17|      20|     487|     504|       9
---------------------------------------------------------------------------
  481-  502 (16.74/10.86)	SDldvsVAQQDA.LSATLeSANT
  503-  522 (19.80/ 8.15)	SD..pkINKNDAqVSASV.SCDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.08|      14|      15|    1458|    1471|      10
---------------------------------------------------------------------------
 1458- 1471 (22.44/10.70)	SHMQQVASSASAAS
 1474- 1487 (23.64/11.77)	SGVPQVTQSKPSSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.63|      17|      28|     716|     736|      11
---------------------------------------------------------------------------
  716-  732 (34.45/11.85)	QSMQ..MQLQSGSGSGGSG
  744-  762 (22.19/ 6.92)	RSLQalMQSQGASTSAAAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.13|      13|      15|    1681|    1694|      13
---------------------------------------------------------------------------
 1681- 1694 (19.74/14.59)	F.SMPSkKSSVHAAL
 1698- 1711 (19.39/ 8.86)	FpSMGS.KSKLDDTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.55|      15|      15|    1354|    1368|      15
---------------------------------------------------------------------------
 1354- 1368 (23.98/18.17)	LEVIQPATVKQQKLE
 1372- 1386 (28.56/23.41)	LEMCMIRWFKDFALE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.44|      16|      22|    1561|    1576|      16
---------------------------------------------------------------------------
 1561- 1576 (27.08/16.35)	DVETERAKLHALLNSS
 1582- 1597 (29.36/18.44)	DWESEIANMEALSGSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.31|      22|      22|     528|     549|      17
---------------------------------------------------------------------------
  528-  549 (35.31/20.82)	SEAAGKAQGTGVQTGDAGELDI
  551-  572 (34.00/19.69)	SEKKENEKETKESTADAPAVEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.05|      16|      22|    1757|    1772|      18
---------------------------------------------------------------------------
 1757- 1772 (29.05/15.91)	LPSS...KKPQIPPSVSVT
 1776- 1794 (23.00/10.78)	LQSSsnqQSNQKPFTITVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.14|      24|      24|    1022|    1045|      19
---------------------------------------------------------------------------
 1022- 1045 (37.85/25.32)	EKRFIRELEAQIQRTIKLEAFNAE
 1048- 1071 (34.29/22.16)	EKLAAAEIAAATEKAAATEKATAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.17|      21|      23|     276|     298|      21
---------------------------------------------------------------------------
  276-  296 (37.28/14.31)	GSASGSNSGNTTPAHKSSALD
  299-  319 (31.89/16.66)	DKDSGGINASAVAAAVTSIHD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.19|      16|      24|    2104|    2123|      22
---------------------------------------------------------------------------
 2104- 2123 (17.22/22.60)	ALDqAAlqfGSLAGLNPS..LL
 2131- 2148 (24.97/13.83)	AFD.PK...NPLAAFDPKnpLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.79|      10|      48|      72|      81|      23
---------------------------------------------------------------------------
   72-   81 (20.10/ 9.23)	GLGAADH.QAA
  117-  127 (16.70/ 6.38)	GLGAYGHpQAA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25093 with Med12 domain of Kingdom Metazoa
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