<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25082

Description GM12862
SequenceMVSLIDTIEAAAEKQKQSQAVATNSSASSSSSSCSSMFTASPPSSSVGSPSPGAPKTNLTASGKPKEKRRNNEKRKEKSRDAARCRRSKETEIFIELSAALPLKTDDVNQLDKASVMRITIAFLKIREMLQFVPSLRDCNDAIKQDIETAEDQQEVKPKLEMGSEDWLNGAEARELLKQTMDGFLLVLSHEGDITYVSENVVEYLGITKIDTLGQQIWEYSHQCDHAEIKDALSLKRELAQKVKDEPQQNSGVSTHHRDLFVRLKCTLTSRGRSINIKSASYKVIHITGHLVVNAKGERLLMAIGRPIPHPSNIEIPLGTSTFLTKHSLDMHFTYVDDKMHDLLGYLPKDLLDTSLFSCQHGADSERLMATFKSVLSKGQGETSRYRFLGKYGGYCWILSQATIVYDKLKPQSVVCVNYVISNLENKHEIYSLAQQTAASEQKEQHHQAAETKKEPEKGTDPEIILQETKETANTPIPLELQAKPLQIESEKAEKTIEETKTTATIPPVTATSTADQIKQLPESNPYKQILQAELLIKRENHSPGPRTITAQLLSGSSSGLRPEEKRPKSVTASVLRPSPAPPLTPPPTAVLCKKTPLGVEPTLPPTTTATAAIISSSNQQLQIAQQTQLQNPQQPAQDMSKGFCSLFADDGRGLTMLKEEPDDLSHHLASTNCIQLDEMTPFSDMLVGLMGTCLLPEDINSLDSTTCSTTASGQHYQSPSSSSTSAPSNTSSNNNSYANSPLSPLTQTPTATASNPSHQQQQQQHHNQQQQQQQQQQHHAQHHDNSNSSSNIDPLFNYREESNDTSCSQHLHSPSITSKSPEDSSLPSLCSPNSLTQEDDFSFEAFAMRAPYIPIDDDMPLLTETDLMWCPPEDLQTMVPKEIDAIQQQLQQLQQQHHQQYAGNTGYQQQQQQQPQLQQQHFSNSLCSSPASTVSSLSPSPVQQHHQQQQAAVFTSDSSELAALLCGSGNGTLSILAGSGVTVAEECNERLQQHQQQQQQSGNEFRTFQQLQQELQLQEEQQQRQQQQQQQQQQQQLLSLNIECKKEKYDVQMGGSLCHPMEDAFENDYSKDSANLDCWDLIQMQVVDTEPVSPNAASPAPCKVSAIQMLQQQQQLPQQNIILNAVPLITIQNNKELMQQQQQQEQLQQPAIKLLNGASIAPVTTKATIRLVESKPPTTTQPRVAKVNLVPQQQQQHGNKRHLNSATGAGNPVESQGLGGGGSVRLEGQSGESKQQKQQQQQSNSVLKNLLVSGRDVSAGYCIVPMRPKKQLAKV
Length1276
PositionKinase
OrganismDrosophila sechellia (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.04
Grand average of hydropathy-0.691
Instability index67.11
Isoelectric point5.79
Molecular weight140886.86
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
protein dimerization activity	GO:0046983	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25082
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     848.80|     135|     135|     763|     897|       1
---------------------------------------------------------------------------
  445-  568 (122.87/38.45)	.............QH.HQAAETKK..EPEKGT......DPEI...ILQETK...ET..ANT.P.IPLElQAKPLQIESEKAEKTIEETKttaTIPPVTATSTAD......QIKQLPE...........................................S.....nPYKQILQ.................................AELLI....................KREN.......HSpgprtitAQLL..SGSSSGLRP....E..EKRP
  569-  685 (123.52/38.69)	KSVTASV........LR.P...........SPAPPLT.PPPT.avLCK...........KT.P..........LGVEPTL...PPTTTA...TAAI..ISSSNQ......QLQIAQ...................................................QTQLQNP.................................QQPAQdmskgfcslfaddgrgltmlKEEP.......DD.......LSHHLASTNCIQLDEM...T..PFSD
  702-  801 (159.17/51.65)	SLDSTTCSttasgQHYQSPSSSST..SA.....PSNT.SSNN............NSYA.NS.P..........LS........PLT..Q...T..PTA.TA.SN......PSHQ..Q...........................................Q......QQQHHNQ.................................QQQQQ....................QQQQ.......HH.......AQHHDNSNSSSNIDPL...F..NYRE
  802-  939 (222.91/74.84)	ESNDTSCS.....QHLHSPSITSK..SPEDSSLPSLC.SPNS...LTQEDDFSFEAFAMRA.PYIPID.DDMPLLTETDLMWCPPEDLQ...TMVPKEIDAIQQ......QLQQLQQ...........................................Q.........HHQQ..........................yagntgyQQQQQ....................QQPQ.......LQ.......QQHFSNSLCSSPASTV...S..SL.S
  940- 1072 (135.69/43.11)	PSPVQQHH.....QQQQAAVFTSD..SSELAAL..LCgSGNG....T....LSI..LA.........G.SGVTVAEE.....C.NERLQ...QHQQQQ....QQsgnefrTFQQLQQ...........................................ElqlqeeQQQRQQQ.................................QQQQQ....................QQQQllslnieCK.......KEKYDVQMGGSLCHPMedaFenDYSK
 1073- 1246 (84.64/24.54)	DSANLDCW.....DLIQMQVVDTEpvSPNAAS.PAPC.KVSAiqmLQQQQQLPQQNIILNAvPLITIQ.NN......KELMQQ...................QQ......QQEQLQQpaikllngasiapvttkatirlveskpptttqprvakvnlvpqQ......QQQHGNKrhlnsatgagnpvesqglggggsvrlegqsgesKQQKQ....................QQQQ....................SNS...................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.91|      42|     212|     101|     231|       2
---------------------------------------------------------------------------
  184-  225 (74.57/140.02)	FLLVLSHEGDITYVSENVVEYLGITKIDTLGQQIWEYSHQCD
  323-  364 (76.34/13.29)	FLTKHSLDMHFTYVDDKMHDLLGYLPKDLLDTSLFSCQHGAD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25082 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KATIRLVESKPPTTTQPRVAKVNLVPQQQQQHGNKRHLNSATGAGNPVESQGLGGGGSVRLEGQSGESKQQKQQQQQSNSVLKN
2) PKEIDAIQQQLQQLQQQHHQQYAGNTGYQQQQQQQPQLQQQHFSNS
3) QILQAELLIKRENHSPGPRTITAQLLSGSSSGLRPEEKRPKSVTASVLRPSPAPPLTPPPTAVLCKKTPLGVEPTLPPTTTATAAIISSS
4) SLAQQTAASEQKEQHHQAAETKKEPEKGTDPEIILQETKETANTPIPLELQAKPLQIESEKAEKTIEETKTTATIPPVTATSTADQIKQLPESNP
5) SLDSTTCSTTASGQHYQSPSSSSTSAPSNTSSNNNSYANSPLSPLTQTPTATASNPSHQQQQQQHHNQQQQQQQQQQHHAQHHDNSNSSSNIDPLFNYREESNDTSCSQHLHSPSITSKSPEDSSLPSLCSPNSLTQEDDFSFEAFAMRAPYIPIDDD
6) SSSCSSMFTASPPSSSVGSPSPGAPKTNLTASGKPKEKRRNNEKRKEKSRDAARC
1167
881
529
432
702
31
1250
926
618
526
859
85










Molecular Recognition Features






MoRF SequenceStartStop




NANANA