<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25077

Description GM20262
SequenceMASSLNKTRHRRRLAAISFLSNISLDGTHRDTKFGATFGSSLLCNQNKNPSSLGLGSGGFHPHYQQHHHQRSHSATHHNHQKRHHTQQQQQQHTQQQQQQRQHQQQHQQQQQPNQQHQNGALCSPLLCSADVHMGIDGGIGLGLGLEDCTTGASDGDGHFSETENMGQYLMNVLPAADHNRSSIVPAERRNIKRPTSSGRHNHQAPGNGNMGNKLQQQQQQQRQARSCAAGSGGSGAESGSDSDSVKIPLKVSNLGSGGGVSGGAGSKLLPLRERTFSNGASDQNLQPERRARLNTAPGMRVGSNSSIAMGGGLKRTYVLSGSSVSHITDDSSTESLTPAGNYAGSFRNSVSKSVQISDSRRGTSGQPLGLGQARDERMVLVSRKIPFFIFSSLPYYKGKNGRAEFRKEDRRRRNPSTSRPLSSINDAPFDPFDLLGIQKAESGQDISYGHLLIPSRQYEKERKKHGNASANPSIFENQMEITSTAALKNHGIARCFTYENNNRNSATSPTPDMKLDMDIESVILGGDSSRGQVYSASILDDPELIAGKHRTLLTFTSYMTSVIDYVRPSDLKKELNDKFREKFPTIQLTLSKLRSIKREMRRINKLDSRIDLVTISQAYVYFEKLILANLINKSNRKLCAGACLLLSAKMNDVKGDALKSLIEKTESVFRLNRKELISSEFAVLVALEFSLHVSRHEVLPHYQRLLYES
Length710
PositionKinase
OrganismDrosophila sechellia (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.05
Grand average of hydropathy-0.721
Instability index55.94
Isoelectric point9.74
Molecular weight78391.78
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
regulation of cell cycle	GO:0051726	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25077
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     100.64|      16|      16|      81|      96|       1
---------------------------------------------------------------------------
   66-   81 (29.26/14.35)	QHHHQRS.HSATHHNH..Q
   82-   99 (25.73/11.75)	KRHHTQQ.QQQQHTQQqqQ
  100-  115 (20.91/ 8.21)	QRQHQQQhQQQQQPNQ...
  189-  204 (24.74/11.02)	RRNIKRP.TSSGRHNH..Q
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.99|      23|      23|     231|     253|       2
---------------------------------------------------------------------------
  231-  253 (38.54/17.30)	GSGGSGAESGSDSDSVKIPLKVS
  256-  275 (29.85/11.87)	GSGG.GVSGGAGSK..LLPLRER
  336-  358 (30.61/12.35)	SLTPAGNYAGSFRNSVSKSVQIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.33|      16|      18|       4|      21|       3
---------------------------------------------------------------------------
    4-   21 (19.47/17.96)	SLNKTrHR.RRLAAiSFLS
   24-   40 (25.86/13.42)	SLDGT.HRdTKFGA.TFGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.01|      27|      33|     362|     388|       5
---------------------------------------------------------------------------
  362-  388 (47.00/27.29)	RGTSGQPLGLGQARDERMVLVSRKI......PF
  398-  430 (42.01/23.65)	KGKNGRAEFRKEDRRRRNPSTSRPLssindaPF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.84|      10|      23|     128|     138|       6
---------------------------------------------------------------------------
  128-  138 (16.12/14.41)	CSADVHMGiDG
  149-  158 (19.73/12.07)	CTTGASDG.DG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25077 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GIGLGLGLEDCTTGASDGDGHFSETENMGQYLMNVLPAADHNRSSIVPAERRNIKRPTSSGRHNHQAPGNGNMGNKLQQQQQQQRQARSCAAGSGGSGAESGSDSDSVKIPLKVSNLGSGGGVSGGAGSKLLPLRERTFSNGASDQNLQPERRARLNTAPGMRVGSNSSI
2) MASSLNKTRHRRRLAAISFLSNISLDGTHRDT
3) NQNKNPSSLGLGSGGFHPHYQQHHHQRSHSATHHNHQKRHHTQQQQQQHTQQQQQQRQHQQQHQQQQQPNQQHQNGALCSPL
139
1
45
308
32
126










Molecular Recognition Features






MoRF SequenceStartStop




1) KLLPLR
268
273