<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25036

Description GL22046
SequenceMQEVCSTLDTTPMGTQIKSESPLNPLQVQTGGQTALPVGVGVGGLVGQGTQQGAPAVPAVMLVNKMASNCDKRAADTAYWMAASEGGFINSQPSMAEFLNHLSPESPKMGTPVGGGGGVGVGVGGGVNVNVNVGVGYPVGVGPMPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGSLTPNSSLETGISSNLLGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDENQVIKKEAVSTSSKASPFGYESSTPSLVSFRRDSDAVIASANPPPTKGKKRYQNNANSIATPTPLTDSNSGGNVGAGGGGGASAGGYFPGYYPSPKQQMQQQQQLHPQQQQQQPQPQDYYGKYDIEFAASPHHNNPHKQQSLHAGEYLSPKPNAATFHQNSQQQQQHDQQFYYNYNDANGSAYMNHQQQQQQQHHHVGDFETPPINGPSNFNSGYYDNMSFQHQAQAQAHQQHQSVVFQQQQQHQQAPINHQQHMHHLGTGEAYSALGLQMENCDGYNNFGGPGSAGAGSAGAGVGVGYYEAGQQPPVPPHTHTHTHHPHHHVQVQAQAHAHLHAHHNPAAAAVQAGVGVGVGVGVVPPPPPPSHIHGFALNGGGPAVQSQAFVSGGGSAGGAAAISGLENSNSSSDFNFLSNLANDFAPEYYQLS
Length797
PositionKinase
OrganismDrosophila persimilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.06
Grand average of hydropathy-0.779
Instability index54.67
Isoelectric point6.11
Molecular weight84824.44
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
DNA-binding transcription factor activity, RNA polymerase II-specific	GO:0000981	IEA:InterPro

GO - Biological Process
proboscis development	GO:0048728	IEA:EnsemblMetazoa
specification of segmental identity, labial segment	GO:0007381	IEA:EnsemblMetazoa
specification of segmental identity, maxillary segment	GO:0007382	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25036
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     414.36|      78|      78|     477|     554|       1
---------------------------------------------------------------------------
  357-  431 (49.39/13.05)	...................DIE.....ESSPIKVKKKDENQVIKKEA..VS...TSSKA.S.........................PFGYESstpslvsfrrdsdaviasaNPPPTKGKKRY..QNN.....ANSIA.
  432-  478 (33.90/ 6.93)	.......TPTPlTDSNSGGNVGAggggGAS.............AGGY..FPgyyPSPK..............................QQMQ...................QQQQLHP....................
  479-  554 (140.77/49.16)	..QQQQQQPQP.QDYYGKYDIEF....AASPHHNNPHKQQSLHAGEY..LS...PKPNA.A.........................TFHQNS...................QQQQQHDQQFYYNYND.....ANGSAY
  557-  635 (96.50/31.67)	HQQQQQQQ....HHHVG..DFE.......TPPINGPSNFNS...GYYdnMS...FQHQAqA.........................QAHQQH..............qsvvfQQQQQH.QQAPINHQQhmhhlGTGEAY
  670-  765 (93.79/30.60)	YYEAGQQPPVP.PHTH.....TH....THHPHHHVQVQAQA.HAHLH..AH...HNPAA.AavqagvgvgvgvgvvppppppshihGFALNG...................GGPAVQSQAFVSGGGS.....AGGAA.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     163.85|      36|      78|      23|      81|       2
---------------------------------------------------------------------------
   23-   58 (67.50/23.02)	LNPLQVQTGG......QTALPVGVGVGGLVGQG....TQQGAPAVP
   99-  120 (15.17/20.43)	LNHLS.....pespkmGTPVGGGGGVG...................
  121-  155 (47.86/14.32)	.....VGVGG......GVNVNVNVGVGYPVGVGpmpqTPDGMDSVP
  715-  735 (33.32/ 6.24)	.....VQAG............VGVGVG..VGVV....PPPPPPS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.70|      29|      31|     248|     278|       4
---------------------------------------------------------------------------
  240-  261 (22.56/ 9.31)	............NRRMKHK.rQTLSKTDDEDNKDS
  264-  280 (15.51/ 6.65)	G....DDDQSDSNSNSKKS.cQ.............
  281-  315 (40.63/20.80)	GcelpSDDIPDSTSNSRGHnnNTPSATNNNPSAGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.80|      15|      25|     182|     196|       5
---------------------------------------------------------------------------
  182-  196 (27.89/20.13)	EFVPENGL..PRRLRTA
  208-  224 (23.91/16.15)	EFHFNKYLcrPRRIEIA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25036 with Med12 domain of Kingdom Metazoa
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