<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25029

Description GL23418
SequenceMEVDQLSLADVVFVIEGSAINGAYINELKTNYILPTLEHFTTGSIDEREYLIADRFATLYGIVVYRTASNLLEPVCATYGPFLQPQKVMETIERLPLVGGGMESCAHMAEGFAAAHGCFEDISERRQMLDQTNVQRHCILICNSPPYQMPVTESWKYLGKSCEQLAGLFNERKINLSIIAPRKMPILFKLFMKADGDQPITSKNYAKNIRHLVLLKGYSLKERAASPNSMAAQMAAPSTAQAAVQQQQQQQNPGGQQQAGSGMPMDTTSAQQQQQQQQQQGGPPQQQQQVMNMNPMHQQQQQQQPGPNPQAGLLNPQQQQQLMQQQQQNQFVPQNQMQNPNFQQNVVPGQNRWMYPNQQGQARPPFMQQGAAGGGGNMQQQLQQQQQQNANSALISRINAPPNQTVNSLQQQQQQQRLQMLNQQQFNQQLQQQLVQQQQQQGQQQQQQQGNPNASNMMPAVSNAGNMPNPQQQQVAQQVAQQNPQQQAQVQVQQQQQQQQSNPQQQQEQASLREKIWTGLLEWSEKPKNDPQKIPHTLQCTVCTNIKDGEPEIKAENWPPKLLMQLMPKHLVGNIGGQFLKDSKMVVFRPSPGEALDSLAKMMTSGYAGCVHFSSIPNAPACELKVLILLYTPDRNAFLGFIPNNQAMFVERLRKVIQQKQHGNMQQQQQQQMLQQQGKSPMELQQQQQQQQQQQQQQMQQQDNSQQQQQHYNQYQLNMQMQGGGGPGPGGGGGPGPGGVGMPMQQNQMQMNMMQQQQQRMPLGVGVAGGVPNPSLQQQLQQQVAPNVAAMQQQAAQQQRMVRPMMSNNNPGLRQLLQHQTTPGNQFRPQMGGGQNPNQMGGAGGPMVGNRNFDDGSYEFM
Length861
PositionUnknown
OrganismDrosophila persimilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.05
Grand average of hydropathy-0.870
Instability index65.88
Isoelectric point8.76
Molecular weight96370.55
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25029
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     133.52|      23|      23|     658|     680|       1
---------------------------------------------------------------------------
  286-  308 (41.10/ 7.31)	QQQQVMNMNPMHQQQQQQQPGPN
  658-  680 (50.01/10.85)	QQKQHGNMQQQQQQQMLQQQGKS
  684-  705 (42.42/ 7.84)	LQQQQQQQQQQQQQQM.QQQDNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.60|      22|      25|     338|     362|       2
---------------------------------------------------------------------------
  348-  371 (31.95/ 7.94)	PGQNRWMYPNQQGQArPPfMQQGA
  436-  458 (33.65/ 6.85)	QQQQQQGQQQQQQQG.NPnASNMM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.07|      30|     109|     708|     738|       4
---------------------------------------------------------------------------
  708-  737 (61.60/12.58)	QQQHYNQYQLNM.QMQGGGGP.GP.GGGGG.PGP
  743-  774 (44.31/ 6.42)	PMQQ.NQMQMNMmQQQQQRMPlGV.GVAGGvPNP
  818-  848 (51.16/ 8.74)	QHQTTPGNQFRP.QMGGGQNP.NQmGGAGG.PMV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.45|      38|      54|      24|      61|       9
---------------------------------------------------------------------------
   24-   61 (65.44/45.47)	YINELKTNYILPTLEHF.TTGSIDEREYLIADRFATLYG
   79-  117 (64.01/44.31)	YGPFLQPQKVMETIERLpLVGGGMESCAHMAEGFAAAHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.15|      14|      25|     586|     604|      11
---------------------------------------------------------------------------
  586-  599 (23.48/ 8.75)	VVFRPSPGEALDSL
  611-  624 (24.68/18.02)	VHFSSIPNAPACEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.28|      32|     282|     495|     531|      12
---------------------------------------------------------------------------
  495-  531 (54.38/31.07)	QQQQQQSNPQ..QQQEQASLREKIWTGLLewsekPKNDP
  778-  811 (52.90/20.68)	QQLQQQVAPNvaAMQQQAAQQQRMVRPMM.....SNNNP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25029 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AASPNSMAAQMAAPSTAQAAVQQQQQQQNPGGQQQAGSGMPMDTTSAQQQQQQQQQQGGPPQQQQQVMNMNPMHQQQQQQQPGPNPQAGLLNPQQQQQLMQQQQQNQFVPQNQMQNPNFQQNVVPGQNRWMYPNQQGQARPPFMQQGAAGGGGNMQQQLQQQQQQNANSALISRINAPPNQTVNSLQQQQQ
2) QQQQQGQQQQQQQGNPNASNMMPAVSNAGNMPNPQQQQVAQQVAQQNPQQQAQVQVQQQQQQQQSNPQQQQEQASLR
3) RLRKVIQQKQHGNMQQQQQQQMLQQQGKSPMELQQQQQQQQQQQQQQMQQQDNSQQQQQHYNQYQLNMQMQGGGGPGPGGGGGPGPGGVGMPMQQNQMQMNMMQQQQQRMPLGVGVAGGVPNPSLQQQLQQQVAPNVAAMQQQAAQQQRMVRPMMSNNNPGLRQLLQHQTTPGNQFRPQMGGGQNPNQMGGAGGPMVGNRNFDDGSYEFM
224
437
652
414
513
861










Molecular Recognition Features






MoRF SequenceStartStop




NANANA