<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24993

Description Uncharacterized protein
SequenceMKKYNFVCNAILHVYHCGTYVRLLDIATLCAEVTSYSSGLNGEWMGVLRALCCSPSSNFGFTELLTQLEISDSRSADNIAMFTAVLISRHCFSLEELLRLVILPPLHDTRTSRSINQHFKIGAGARLSCHLLLRLLEKPSHEVNSYVDYNSGELVLKSWDRSLLSTWHHTLDLNYIYIVLKTMAAMVDSNKDNNSKDIFNFTTNMGILDEPDTTCANLALNVLKSICAQPLIQQHVLCNLRDCCSKEFLLDSMLTKRQAIYLQYLLCCADSITFDPSDIDTDINKEDVLNLLKDINQWSLRTTWLEIELHIKLCTRNEERTRIIDNLAEAIIKVYQTSNITKCASRSDMSAILSQEGNISLIAPFVAKLSNFAQGHILKAAGEVLERSKWWLPDDDNPCTLNQKPFLSLILTCLRCQDEHKRCFLSSIQKQFQQFLRSPIEERMPDNLKQREFLNDAIHLRLSLIGAVFDTILRDLTLCKDWIRLMLQFIASGTIDLFSEDKQLLSSILDMLSVLISTLNVSESVPSMSDEARKVNASLVKKFRKELDGINSPVVRECKKLFSLETPPVNVISVSSETDDTCYQNELFKTVAVDHSVHVNNWDILESTKFSSPTLWSYFAGVKVDRKPLTYENQFFSTMQHSHMIEESPVFYLPTKELEINPLPSAKPTTSKTVKNRTSNAKTAVPKEITPPSSVIKPEVKATKAAPGKRQRRRSTIKEKEEKRTTPSTITVTNTISKTTAADSMRDRQYLAIGSSSGTARSNATQNNEGFQSLISKQVKVSQPVSSYTISDRSQSETRAPRKNSGTQLRDLLGDMPTAMVYPEAPNVGRSQMQTTMVTSASDYSSFQSMNNNTIANINQGIDSSFSDTLNIASHSDNLSQRSLQQGMTSSLMDNNSMVDNQISTNFMSTRMPVNRSAGRMSQNLINSNSQQSRSNDVLRRLNKFNGHQSHYR
Length953
PositionKinase
OrganismTrichoplax adhaerens (Trichoplax reptans)
KingdomMetazoa
LineageEukaryota> Metazoa> Placozoa> Trichoplacidae> Trichoplax.
Aromaticity0.07
Grand average of hydropathy-0.324
Instability index50.91
Isoelectric point8.19
Molecular weight107378.15
Publications
PubMed=18719581

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coactivator activity	GO:0003713	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24993
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.55|      34|      34|     679|     712|       1
---------------------------------------------------------------------------
  679-  712 (57.44/46.35)	SNAKTAVPKEITPPSSVIKPEVKATKAAPGKRQR
  715-  748 (52.12/41.26)	STIKEKEEKRTTPSTITVTNTISKTTAADSMRDR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.14|      34|      34|     834|     867|       2
---------------------------------------------------------------------------
  831-  864 (56.74/30.50)	SQMQTTMVTSASDYSSFQSMNNNTIANI...NQGIDS
  865-  901 (51.40/27.00)	SFSDTLNIASHSDNLSQRSLQQGMTSSLmdnNSMVDN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.25|      25|     108|      17|      43|       3
---------------------------------------------------------------------------
   17-   43 (39.19/27.83)	CGTYVRLLDIATlcAEVTSYSSGLNGE
  129-  153 (46.05/25.97)	CHLLLRLLEKPS..HEVNSYVDYNSGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.55|      11|     108|     406|     436|       4
---------------------------------------------------------------------------
  394-  404 (21.93/30.71)	DDDNPCTLN..QK
  418-  430 (16.62/17.83)	DEHKRCFLSsiQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.23|      14|     133|      78|     108|       6
---------------------------------------------------------------------------
   59-   72 (23.60/27.20)	FGFTELLTQLEIS...D
   92-  108 (17.64/ 8.48)	FSLEELLRLVILPplhD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.14|      18|      28|     448|     465|       9
---------------------------------------------------------------------------
  448-  465 (28.80/15.07)	LKQREFLNDAIHLRLSLI
  473-  490 (30.34/16.22)	LRDLTLCKDWIRLMLQFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.23|      10|      28|     229|     238|      10
---------------------------------------------------------------------------
  229-  238 (19.53/14.84)	QPLIQQHVLC
  258-  267 (18.71/13.89)	QAIYLQYLLC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.52|      16|      33|     757|     772|      11
---------------------------------------------------------------------------
  757-  772 (28.21/22.71)	SGTARSN..ATQNNEGFQ
  791-  808 (23.32/17.19)	SDRSQSEtrAPRKNSGTQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24993 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FSDTLNIASHSDNLSQRSLQQGMTSSLMDNNSMVDNQISTNFMSTRMPVNRSAGRMSQNLINSNSQQSRSNDVLRRLNKFNGHQSHYR
2) PLPSAKPTTSKTVKNRTSNAKTAVPKEITPPSSVIKPEVKATKAAPGKRQRRRSTIKEKEEKRTTPSTITVTNTISKTTAADSMRDRQYLAIGSSSGTARSNATQNNEGFQSLISKQ
3) SQPVSSYTISDRSQSETRAPRKNSGTQLRDLLGDMPTAMVYPEAPNVGRSQMQTTMVTSASDYSS
866
662
782
953
778
846










Molecular Recognition Features






MoRF SequenceStartStop




NANANA