<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24988

Description "Uncharacterized protein, isoform A"
SequenceMNQYQIQQLTSHLSQALDQNYDVINMDAVLSVICALEGTKITKEQLEATRLAKYINQLRRRTTNEHLARRAKSLLKKWREMVGIQQTTFDSQQQLQTQSIEFLKSTTSTPHFDEIVSLLPISSSLPSQEIFSDIHLNIDRSETPSLSVNSQAHSNLSSPHHNNINDLNRRENNSTNSVHSYNRLSQNMSSGPVNPPQQHLINQSLNTISNKCDVSKKKLNEVSVVIDIVSDSDDNDNNSSKLVRSDISEPSLLMIPSTPSPRLKKNRKDKKNDPILHRPNKKISKKNKDGFLHTTPADSEVYSTSNSSMSSILSGDTTFGNSGSKTRSNSSELTFSGRFKSINQVEVLSQNNFTLFSGNNNASTHINELDKPLFEDYNTYDSSASCSRFSSSVDQGKSEKIALQIHRPVDAQCPVLKKTELFHKASDSHGYKKRGRKKGSRGVDAVISKESSSLCQQIFLGSSTVNKVKTTKELFNEIQSRKLTASHSSTFRDKTKCARLKRRTSSCSEASILSPNLMENYSGNVTLMDIDTFSKKIRESANTDSDTTEHFSNKSQEVKECTSLDSNSCSRQTSSFVNYSKKLTSQSLNDITTQLMHLINSFGSPISVHEVEKSYQVQLVPCSCIIFENNINLLRESKLFTPDDQGNIFNSNGKYNGKLDHNTKEILRTIEQPIDKDDTQPKPKKSIFDLDFEDEDDPLKSLMNAIQKPVGNKETDKILTPQIFTNKVLMSLGNTNIDAQLDSFSQEIDDELPKVVESVFTIKEDPDCLAKKIFYVQTNKVNGFHINALHNYYIPNINGNWDSIDESISFKSINDFVDSLDSYTVTNGSDVVPQYGFLKYDYIRKDLSSLKFLKPYKVKSFQKDFSPFLGVAKCLPTCRNYKRKAIDRHGSADQILKKNKLNRAIPLQIDTEIPISDMISYNNSLTHIKEKDCSNHALNDSFDSCCVSAFSNNLLKLANEKDVHEGQAEHLKSQDHFSPICKNSSNVLRLQNMSYIRKNKTQISKQEKNRKRRGSCGGIKQDFEENTDILRTTKRNKLRLSGTINDRPSGNNSSENDDTMKDIDVEQHGKNEYEIVQRKSSDGGVAGNHIVLTIKKTPKILSETEILKRLSSTPNLNISSLSNSLIEVPFFSKGSKLPICPRNHHLYRQKIRKSYSRKINTVDLDLKHWFCFKHNVENSIKKKRVHKDLFFKDELLRKNLQGRKQKIMNYSSSSSSYDDSDLEYIAVEKNFVKKKKKDEIDTRVKSVLPVTNIKNEEDPSLCSDEDKDMIAIPSTSEIGKNHVDEYEDLRNNGMLLSFNSIVAQQCNLVDNLNSVEVRFSKENGPLDVPQTELNNLCNMNENISVNSLTASDNVNNSKVALGHDKPEIGASLNYQKCRNPVESFKSAELLSVEHRIGIRLSKNNSDNVVKSTKIQKFKEWHQVLQLKSYNDEPLIVMPYVVLE
Length1443
PositionUnknown
OrganismDrosophila ananassae (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.06
Grand average of hydropathy-0.724
Instability index44.76
Isoelectric point8.78
Molecular weight163326.61
Publications
PubMed=17994087
PubMed=18057021

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24988
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     562.36|     149|     163|     134|     292|       1
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  137-  288 (240.27/139.44)	NIDRSETPSLsvNSQAH.........SNLSSPHHNNINDL............NRR.......ENNST.......NSVHSYNRLSQN...MSS.........GPVNPPQQHL..INQSLNTISNKCDvSKKKLNEVSVVIDIVSDSDDNDNNSSKLVRSDISE.PSLLMIP...STPSPRLKKN...RKDKKNDPILHRPNKKISKKNK
  294-  441 (138.25/79.02)	............TTPAD.........SEVYSTSNSSMSSIlsgdttfgnsgsKTR.......SNSSEltfsgrfKSINQVEVLSQNnftLFS.........GN.NNASTHIneLDKPLFEDYNTYD.SSASCSRFSSSV....DQGK.............SE.KIALQIHrpvDAQCPVLKKTelfHKASDSHGYKKRGRKKGSR...
 1252- 1405 (183.83/94.59)	NIKNEEDPSL..CSDEDkdmiaipstSEIGKNHVDEYEDL..............RnngmllsFNSI..........VAQQCNLVDN...LNSvevrfskenGPLDVPQTEL..........NNLCN.....MNE.NISVNSLTAS.DNVNNSKVALGHDKPEiGASLNYQ...KCRNPV..ES...FKSAELLSVEHRIGIRLSKNNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     183.98|      51|      76|     721|     785|       2
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  677-  714 (43.13/17.11)	............................D.DTQPKPKKSI..FDLDfEDEDDPLKSLM..............NAIQKPVGNKE
  721-  785 (76.37/65.36)	PqiftnkvlmslgntNIDAQLDSFSQEID.DELPKVVESV..FTIK.EDPDCLAKKIF..............YVQTNKVNGFH
  795-  862 (64.48/34.75)	P..............NINGNWDSIDESISfKSINDFVDSLdsYTVT.NGSDVVPQYGFlkydyirkdlsslkFLKPYKVKSFQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.11|      17|      22|     544|     563|       3
---------------------------------------------------------------------------
  544-  563 (27.75/24.63)	DSDT....TEHFSNKSqevKECTS
  565-  585 (23.36/12.04)	DSNScsrqTSSFVNYS...KKLTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     281.90|      76|     394|     586|     672|       4
---------------------------------------------------------------------------
  594-  672 (124.58/79.71)	QLMHLINSFGSPISVHEVEKSYQVQlvpCSCI.I..FENNINLLRESKLFTPDDQGNIFN.SNGKYNGKLDHNTKEILRTIEQ
  945-  989 (46.67/17.33)	............................C.CVsA..FSNNLLKLANEKD.VHEGQAEHLK.SQDHFS.PICKNSSNVLR....
  991- 1067 (110.65/52.96)	QNMSYIRKNKTQISKQEKNRKRRGS...CGGI.KqdFEENTDILRTTKRNKLRLSGTINDrPSGNNSSENDDTMKDI..DVEQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.09|      21|      22|    1147|    1167|       5
---------------------------------------------------------------------------
 1147- 1167 (33.92/19.45)	YRQKIRKSYSRKINTVDLDLK
 1172- 1192 (35.17/20.43)	FKHNVENSIKKKRVHKDLFFK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.64|      10|      29|    1072|    1081|       6
---------------------------------------------------------------------------
 1072- 1081 (17.89/12.38)	EYEIVQRKSS
 1103- 1112 (16.75/11.06)	ETEILKRLSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.03|      25|      31|     886|     910|       9
---------------------------------------------------------------------------
  886-  910 (41.43/25.20)	IDRHGSADQILKKNKLNRAIPLQID
  919-  943 (43.60/26.95)	ISYNNSLTHIKEKDCSNHALNDSFD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24988 with Med26 domain of Kingdom Metazoa
Unable to open file!