<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24985

Description Uncharacterized protein
SequenceMTHLMGPTECASAMMGSSMQFHDNGLGLNLTDYSCYTNDYWTTPYLTGGLSPMKQIEACIQTAGKDRSSYKPLEQIDAKLADIETHSTGSTGTVASSHSSASNTSSPTARPSQDVQGTSLLPDYPNGGSEGATGSGSTEVGGASGGAGATSAKKYKSQYKKDSSAENSSSKAAISSSKAEPEQVHPSLAQAVVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHASYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGANWMKQIVSFDKLKLTNNQMDENGHIILNSMHRYQPRFHLVYFAQKNASLDENAHSSNFRTFIFPETSFTAVTAYQNQRVTQLKISSNPFAKGFRDDGTNDVTSGGGSTMSSMSQESQARMKQQQQQQQQQQQQQQHQQQQQLQQQQQQLKEQRSAGSNFSLGCTDLGVEQQQQNGLQLPATPSSSSTSGNSPDLLGYQMDQQLQQQQQQQQQHLQSQQSHQQHQAGQQQSLLHQGQNQAQYGSYHHGYPQTQIQAHPLTPHSSSSASPPAAASATPAANTGATQLNIYSSIGQPYAQEQSNFGAIYHHNAAAAAAAHYHHGHAHSHGHAHGHAPYATAYDKLKVSRHAAAAAYGMGPTYPSFYGSAAHHQMMRPNSYIDLVPR
Length668
PositionKinase
OrganismDrosophila ananassae (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.07
Grand average of hydropathy-0.759
Instability index54.06
Isoelectric point7.10
Molecular weight72728.04
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
DNA-binding transcription factor activity	GO:0003700	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24985
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.96|      16|      16|     406|     421|       1
---------------------------------------------------------------------------
  406-  419 (24.23/ 7.38)	....KQQQQQQQQQQQQQ
  420-  436 (25.41/ 8.08)	QH.qQQQQLQQQQQQLKE
  507-  524 (23.31/ 6.83)	QHqaGQQQSLLHQGQNQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     134.56|      34|      34|     584|     617|       2
---------------------------------------------------------------------------
  547-  581 (32.83/ 9.66)	SSSSAS.........PPAAASATPAANTGATQlniyssiG..QPYA...
  584-  617 (64.92/25.36)	QSNFGAIY......HHNAAAAAAAHYHHGHAH.......S..HGHAHGH
  618-  654 (36.81/11.60)	.APYATAYdklkvsRH....AAAAAYGMGPTY.......PsfYGSAAHH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.06|      30|      34|     439|     468|       3
---------------------------------------------------------------------------
  439-  468 (54.05/22.99)	SAGSNFSLGC.TDLGVEQQQQNGLQ.LPATPS
  473-  504 (46.01/18.61)	SGNSPDLLGYqMDQQLQQQQQQQQQhLQSQQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.20|      34|      44|      88|     130|       4
---------------------------------------------------------------------------
   88-  121 (57.12/20.52)	TGSTGT.VASSHSSASNTSSPTARPSQDVQGTSLL
  133-  158 (29.69/17.88)	TGSGSTeVGGASGGAGATSAKKYK.SQ........
  160-  185 (32.39/ 9.14)	.........KKDSSAENSSSKAAISSSKAEPEQVH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24985 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISSNPFAKGFRDDGTNDVTSGGGSTMSSMSQESQARMKQQQQQQQQQQQQQQHQQQQQLQQQQQQLKEQRSAGSNFSLGCTDLGVEQQQQNGLQLPATPSSSSTSGNSPDLLGYQMDQQLQQQQQQQQQHLQSQQSHQQHQAGQQQSLLHQGQNQAQYGSYHHGYPQTQIQAHPLTPHSSSSASPPAAASATPAAN
2) YKPLEQIDAKLADIETHSTGSTGTVASSHSSASNTSSPTARPSQDVQGTSLLPDYPNGGSEGATGSGSTEVGGASGGAGATSAKKYKSQYKKDSSAENSSSKAAISSSKAEPEQ
369
70
564
183










Molecular Recognition Features






MoRF SequenceStartStop




1) AKKYKSQYKK
152
161