<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24976

Description Uncharacterized protein
SequenceMRTLPLLLALTLLAIGVVAASSSTTSATTTTTAKPKTEEKSKVEVEKPTKEPTSTTKATRQSKALKPGDNRGKRTLYDFGNAGYLYPEVASRRTGYVDNTAGYYPQTGFYNGQNAIGQYSNSFGPSYSPYPQYLEAPEPIIEIIIKDANETLAEEPAQPIVTKKKKKKEKVHVFYVNYKKDQNNKLHLESPIASLNNDDNEEEEEEEEEVIQYPATPLPPVKSTTLRTIIHPDSEKFHSNSGIHVSFGAENKHQTLHILEEHDAESIQRQVVALPPSVGNTRADYGRESNFGRGSGPSANLLFGNYQQSGINYQHQQHQQQLPVQHSNNYFRPPQALVGPPPSYPKPQVQQQVSQLQPQQQQQRPSITQQQLPSTSSQTIFNKLVQQSQYYINHNQQYQQHQQSHQQQAHQQSHQQQQHQQQPHQQQQQQQQQAPQQQQYQKPPNKQVQVPFFPTIPPKSITPAPYQPVKFRPTPAPAAQVKPLPLPVKLDNVNYQQQQQKQLYQPQQQQKLPLQQQSYQFVRQPQFVQQPQFVVRSPTPPPEYYSQQKQQTQQQQQVQHQPHHQSSLSYFDIKPSKETELLKSIPKFEQHITETVHNPVQNSPLPQQQYQQQQQHQQFAYSSTRNEVIHDVPAPNLGPTVSGHYITASSPSGSQQQQSHFSSFPSEASPQPPVYAESTHGQKVMVVTPVPPSANYVTYSQYNQVPNEHVVHVNAQPAAAALQAQASTNFAQQPRQPAVSQISATSTDNSPFSVSTFHSDVFKELEQRHQKDQPKLPAAPKASPIPVAAPTTTPASAPNGKASQTLLQLPDEVPDDLRQQLFSSGILNNADISILDYDKQGDIALENLPAEHLQHFYGAGGGAQIAETNKVLTVVKPNGDKVALSEKQLDRVKQTNSLPQKQNLDVKVVRFDAGQEQSVSEKYLRTDATVVTPVDLAERQQYNRYLPLKINGAQFPIPESEELLGKRIVSVVVLAPVEAQAPASGSSEARSASDVSREVKFLGGELIKTLVKKPTKENFKRWLEKEARTDLELQSVVLLVAKSSDSSSEQEIFMYDIGTGSINRLNGELSSTFVNVAEENASTEDLEHAATLDPSSLESMMHLRRR
Length1106
PositionKinase
OrganismDrosophila ananassae (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.07
Grand average of hydropathy-0.842
Instability index67.51
Isoelectric point6.86
Molecular weight123737.87
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
actin binding	GO:0003779	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24976
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     537.97|      63|      63|     324|     386|       1
---------------------------------------------------------------------------
  284-  323 (43.67/ 8.75)	.....DYGR.....E...SNFGRGSGP........SA.....NLLFGNYQQSGI.NYQ.....HQQH...........QQQLP.............................
  324-  386 (121.02/37.68)	VQHSNNYFR.....P...PQALVGPPP........SY.....PKPQVQQQVSQL.QPQ.....QQQQ......RPSITQQQLP..........STS......SQTIFNKLVQ
  392-  449 (82.43/23.25)	INHNQQYQQhqqshQ...QQA...HQQ........SH.....QQQQHQQQPHQQ.QQQ.....QQQQ......APQ..QQQY.....................QKPPNKQVQ
  469-  523 (61.46/15.41)	VK.....FR.....PtpaPAAQVKPLPlpvkldnvNY........Q.QQQQKQLyQPQ.....QQQK......LP..LQQQ..............S......YQ..F...VR
  528-  599 (63.03/15.99)	VQQPQFVVR.....S...P....TPPP........EYysqqkQQTQQQQQV.QH.QPH.....HQSSlsyfdiKPSKETELLK..........SIPkfeqhiTETVHNP...
  600-  631 (49.89/11.08)	VQNS......................................PLP..QQQYQQ..QQQ.....HQQF......AYS.................STR......NEVIHD....
  690-  767 (66.64/17.34)	VPPSANYVT.....Y...SQYNQVPNE........HV.....VHVNAQPAAAAL.QAQastnfAQQP......RQPAVSQISAtstdnspfsvSTF......HSDVFKELEQ
  778-  823 (49.83/11.06)	AAPKASPI......P...VAAPTTTPA........SA.....PNGKASQTLLQL..P........DE......VPDDLRQQLF..........S..................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.50|      15|      16|      73|      88|       2
---------------------------------------------------------------------------
   73-   88 (26.52/21.87)	KRTLYDFGNAGYlYPE
   92-  106 (30.99/20.56)	RRTGYVDNTAGY.YPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.58|      11|      15|     136|     146|       3
---------------------------------------------------------------------------
  136-  146 (19.18/10.13)	APEPIIEIIIK
  153-  163 (19.39/10.33)	AEEPAQPIVTK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     174.95|      58|      62|     970|    1030|       4
---------------------------------------------------------------------------
  970- 1030 (85.47/72.81)	SVVVLapVeAQAPASGSSEARSASDVSR.EVKFLGGELIKTLVKKPTKENFKRWLEKEARTD
 1035- 1093 (89.48/63.99)	SVVLL..V.AKSSDSSSEQEIFMYDIGTgSINRLNGELSSTFVNVAEENASTEDLEHAATLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.01|      15|      15|     862|     876|       5
---------------------------------------------------------------------------
  862-  876 (23.76/17.07)	GAQIAETNKVLTVVK
  879-  893 (24.24/17.57)	GDKVALSEKQLDRVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.74|      37|      53|     184|     220|       7
---------------------------------------------------------------------------
  184-  220 (64.94/38.63)	NKLHLESPI.ASLNNDDNEEE....EEEEEEVIQYPATPLPP
  235-  276 (54.79/31.42)	EKFHSNSGIhVSFGAENKHQTlhilEEHDAESIQRQVVALPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.17|      16|     206|     453|     468|       8
---------------------------------------------------------------------------
  453-  468 (33.51/13.83)	FPTIPPKSIT...PAPYQP
  638-  656 (22.95/ 7.16)	GPTVSGHYITassPSGSQQ
  661-  673 (23.71/ 7.64)	FSSFPSEA.S...PQP..P
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24976 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ELLKSIPKFEQHITETVHNPVQNSPLPQQQYQQQQQHQQFAYSSTRNEVIHDVPAPNLGPTVSGHYITASSPSGSQQQQSHFSSFPSEASPQPPVYAESTHGQKVMVVTPV
2) FHSNSGIHVSFGAENKHQTLHILEEHDAESIQRQVVALPPSVGNTRADYGRESNFGRGSGPSANLLFGNYQQSG
3) LHLESPIASLNNDDNEEEEEEEEEVIQYPATPL
4) NYQHQQHQQQLPVQHSNNYFRPPQALVGPPPSYPKPQVQQQVSQLQPQQQQQRPSITQQQLPSTSSQT
5) QPQFVVRSPTPPPEYYSQQKQQTQQQQQVQHQPHHQSSLSYFDI
6) STFHSDVFKELEQRHQKDQPKLPAAPKASPIPVAAPTTTPASAPNGKASQTLLQLPDEVP
7) TTSATTTTTAKPKTEEKSKVEVEKPTKEPTSTTKATRQSKALKPGDNRG
8) VPNEHVVHVNAQPAAAALQAQASTNFAQQPRQPAVSQISATSTDNS
9) YINHNQQYQQHQQSHQQQAHQQSHQQQQHQQQPHQQQQQQQQQAPQQQQYQKPPNKQVQVPFFPTIPPKSITPAPYQPVKFRPTPAPAAQVKPLPLPVKLDNV
580
237
186
312
530
755
24
705
391
690
310
218
379
573
814
72
750
493










Molecular Recognition Features






MoRF SequenceStartStop




1) PYQPVKFR
465
472